Flaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovaries

scientific article published on 26 February 2016

Flaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovaries is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JSBMB.2016.02.028
P932PMC publication ID4821676
P698PubMed publication ID26925929

P2093author name stringDale Buchanan Hales
Chunqi Gao
Karen Hales
Anushka Dikshit
Carrie Small
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Supplementation of flaxseed oil diminishes skin sensitivity and improves skin barrier function and conditionQ33751008
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The SMRT coregulator enhances growth of estrogen receptor-α-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosisQ34068293
Uncovering molecular events associated with the chemosuppressive effects of flaxseed: a microarray analysis of the laying hen model of ovarian cancerQ34151007
Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptorQ34177449
Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cellsQ34313662
Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude miceQ34372085
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Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgeryQ34601463
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The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growthQ42800609
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WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferationQ34770234
Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent mannerQ35654212
A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα proteinQ35907414
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Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells.Q36027812
Enhanced MAF Oncogene Expression and Breast Cancer Bone MetastasisQ36377960
Age dependent increase in prostaglandin pathway coincides with onset of ovarian cancer in laying hensQ36670219
Disrupting insulin-like growth factor signaling as a potential cancer therapyQ36712708
Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancerQ36955081
Targeting BIG3-PHB2 interaction to overcome tamoxifen resistance in breast cancer cellsQ37217695
Flaxseed enriched diet-mediated reduction in ovarian cancer severity is correlated to the reduction of prostaglandin E(2) in laying hen ovariesQ37263044
Long term consumption of flaxseed enriched diet decreased ovarian cancer incidence and prostaglandin E₂in hensQ37300432
Regulation of breast cancer metastasis by IGF signalingQ37334032
CYP1B1 expression in ovarian cancer in the laying hen GallusdomesticusQ37340998
Anti-inflammatory effects of fish oil in ovaries of laying hens target prostaglandin pathwaysQ37418407
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PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an updateQ38259986
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Hydroxyl radical-scavenging property of secoisolariciresinol diglucoside (SDG) isolated from flax-seedQ38559063
Enhanced expression of retinoic acid receptor alpha (RARA) induces epithelial-to-mesenchymal transition and disruption of mammary acinar structuresQ38949355
Insights into significant pathways and gene interaction networks underlying breast cancer cell line MCF-7 treated with 17β-estradiol (E2).Q39104752
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Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activityQ39755236
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Involvement of c-Fos in fenretinide-induced apoptosis in human ovarian carcinoma cellsQ40612715
Activation of the aryl hydrocarbon receptor by some vegetable constituents determined using in vitro reporter gene assayQ40658788
Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancerQ40769199
Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cellsQ41060222
The mammalian metabolite, 2-methoxyestradiol, affects P53 levels and apoptosis induction in transformed cells but not in normal cellsQ41100367
Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned mediaQ41519206
Retinoic acid and estrogen modulation of insulin-like growth factor binding protein-4 gene expression and the estrogen receptor status of human breast carcinoma cellsQ41546720
Dietary flaxseed supplementation and experimental metastasis of melanoma cells in miceQ42452081
P304page(s)73-85
P577publication date2016-02-26
P1433published inThe Journal of Steroid Biochemistry and Molecular BiologyQ15708871
P1476titleFlaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovaries
P478volume159

Reverse relations

cites work (P2860)
Q38696508Enterolactone has stronger effects than enterodiol on ovarian cancer.
Q64285087Pro-apoptotic and anti-angiogenic actions of 2-methoxyestradiol and docosahexaenoic acid, the biologically derived active compounds from flaxseed diet, in preventing ovarian cancer
Q41601838Role of Insulin-like Growth Factor, Insulin-like Growth Factor Receptors, and Insulin-like Growth Factor-binding Proteins in Ovarian Cancer
Q55004540Whole flaxseed diet alters estrogen metabolism to promote 2-methoxtestradiol-induced apoptosis in hen ovarian cancer.

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