Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits

scientific article published on July 1989

Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.9.7.2806
P932PMC publication ID362746
P698PubMed publication ID2476658

P2093author name stringO M Rosen
R S Garofalo
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Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. Affinity-purified insulin-like growth factor I receptor kinase is activated by tyrosine phosphorylation of its beta subunitQ28678245
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificityQ33880454
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Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulinQ34584120
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An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activityQ37537629
Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cellsQ37580262
Insulin receptors are widely distributed in the central nervous system of the ratQ40141863
Effects of insulin, insulin-like growth factor-II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neuronsQ41450398
Adult-level insulin binding is present in term fetal rat CNS membranesQ41598414
Insulin-like growth factor I receptors in neuronal and glial cells. Characterization and biological effects in primary cultureQ42506029
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Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.Q43526073
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Central nervous system insulin receptors in normal and diabetic ratsQ66959356
Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cellQ68994039
The human placenta contains two distinct binding and immunoreactive species of insulin-like growth factor-I receptorsQ69381165
Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivoQ69570919
Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activationQ69592877
Antibodies to deduced sequences of the insulin receptor distinguish conserved and nonconserved regions in the IGF-I receptorQ69610078
Purification and characterization of the receptor for insulin-like growth factor IQ70016330
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulationQ70036344
Insulin and insulin-like growth factor 1 receptors during postnatal development of rat brainQ70059679
Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors?Q70195291
Insulin Binding in Four Regions of the Developing Rat BrainQ70302003
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulinQ70322324
Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptorsQ70864764
The high affinity insulin receptor mediates growth stimulation in rat hepatoma cellsQ71454656
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectnervous systemQ9404
P304page(s)2806-2817
P577publication date1989-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInsulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits
P478volume9

Reverse relations

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