A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer

scientific article published on 2 April 2015

A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JNCI/DJV037
P932PMC publication ID4822523
P698PubMed publication ID25838448
P5875ResearchGate publication ID274394935

P50authorVladimír BenckoQ11903559
Eleonóra FabiánováQ13408494
Paolo BoffettaQ3362604
Jan LubińskiQ11718282
David ZaridzeQ18044189
Jolanta LissowskaQ28606996
Xavier CastellsaguéQ28919226
Valerie GaborieauQ30090004
Ivana HolcátováQ30114366
Paul BrennanQ30114382
Keitaro MatsuoQ30506416
Lenka ForetováQ30830691
Vladimír JanoutQ30830731
Kristina KjaerheimQ30831200
Maxime P ValléeQ39970007
Graham ByrnesQ60781201
Maria TimofeevaQ64609845
Pagona LagiouQ73549595
Ariana ZnaorQ87699151
Stefania BocciaQ88575370
Sérgio KoifmanQ91584296
Marcin LenerQ92201896
Manoj B MahimkarQ99557520
Thangarajan RajkumarQ100440532
Manon Delahaye-SourdeixQ114341807
Neonilia Szeszenia-DabrowskaQ114341808
Victor Wünsch-FilhoQ114384025
Leticia Fernández GarroteQ114384027
Ioan Nicolae MatesQ114384040
Devasena AnantharamanQ114384041
Tanuja A SamantQ114384084
Maria Paula CuradoQ40169536
Wolfgang AhrensQ40539354
Claire M. HealyQ42909717
Tatiana V MacfarlaneQ42909745
Antonio AgudoQ42909755
Jose Eluf-netoQ43099075
Jerry PoleselQ46784421
Nalin ThakkerQ55113357
Silvia FranceschiQ56417107
Lorenzo RichiardiQ56440667
Cristina CanovaQ56521500
David I ConwayQ56521507
Ewa JaworowskaQ58406022
P2093author name stringJames D McKay
Ana Menezes
Luigi Barzan
Amélie Chabrier
P2860cites workEstimates of worldwide burden of cancer in 2008: GLOBOCAN 2008Q27860674
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Mechanism of homologous recombination: mediators and helicases take on regulatory functionsQ28259452
RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombinationQ28274789
Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profileQ28294205
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancerQ28943461
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
Biallelic inactivation of BRCA2 in Fanconi anemiaQ29616130
Population substructure and control selection in genome-wide association studiesQ33348644
The role of homologous recombination processes in the repair of severe forms of DNA damage in mammalian cellsQ33601047
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortiumQ33855653
Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle controlQ33904749
Cancer risks in BRCA2 mutation carriersQ34504452
Squamous Cell Carcinoma - Similarities and Differences among Anatomical SitesQ35220347
Family history of cancer: pooled analysis in the International Head and Neck Cancer Epidemiology ConsortiumQ37011979
Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: a replication study in IndiaQ37558430
A polymorphic stop codon in BRCA2Q71735471
Functional evaluation and cancer risk assessment of BRCA2 unclassified variantsQ95814860
Comparison between self-reported facial flushing after alcohol consumption and ALDH2 Glu504Lys polymorphism for risk of upper aerodigestive tract cancer in a Japanese populationQ43046366
Cancer risks in BRCA2 families: estimates for sites other than breast and ovary.Q43073144
Human papillomavirus infections and upper aero-digestive tract cancers: the ARCAGE studyQ43777296
Mutations in Fanconi anemia genes and the risk of esophageal cancerQ47857337
Germline BRCA2 mutations and the risk of esophageal squamous cell carcinomaQ47870583
Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer.Q50156693
Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions.Q54393225
Cancer incidence in persons with Fanconi anemia.Q55036178
P433issue5
P407language of work or nameEnglishQ1860
P577publication date2015-04-02
P1433published inJournal of the National Cancer InstituteQ400279
P1476titleA rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer
P478volume107

Reverse relations

cites work (P2860)
Q52630405A novel BRCA2 mutation in prostate cancer sensitive to combined radiotherapy and androgen deprivation therapy.
Q38641350Alcohol and head and neck cancer
Q36504154Association between the Cyclin D1 G870A polymorphism and the susceptibility to and prognosis of upper aerodigestive tract squamous cell carcinomas: an updated meta-analysis
Q88692136Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin
Q37002955BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
Q38787257Differential analysis of mutations in the Jewish population and their implications for diseases.
Q52647099Incidental and clinically actionable genetic variants in 1005 whole exomes and genomes from Qatar.
Q40040780International cancer seminars: a focus on esophageal squamous cell carcinoma
Q40081082Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer.
Q64123909Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer
Q37261018Rare variants in BRCA2 and CHEK2 are associated with the risk of urinary tract cancers
Q35203356The 12p13.33/RAD52 locus and genetic susceptibility to squamous cell cancers of upper aerodigestive tract
Q34674332The Molecular Taxonomy of Primary Prostate Cancer
Q89647010Treatment of Pediatric Glioblastoma with Combination Olaparib and Temozolomide Demonstrates 2-Year Durable Response

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