Hsp70 chaperone-based gel composition as a novel immunotherapeutic anti-tumor tool

scientific article published on 12 December 2012

Hsp70 chaperone-based gel composition as a novel immunotherapeutic anti-tumor tool is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12192-012-0391-X
P932PMC publication ID3631097
P698PubMed publication ID23233202

P2093author name stringBoris A Margulis
Irina V Guzhova
Elena Yu Komarova
Katerina M Pankratova
Sergey V Abkin
P2860cites workImmunotherapeutic targeting of membrane Hsp70-expressing tumors using recombinant human granzyme BQ28729023
Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responsesQ34115645
Antitumor activity of mixed heat shock protein/peptide vaccine and cyclophosphamide plus interleukin-12 in mice sarcomaQ34668901
Heat shock protein derivatives for delivery of antigens to antigen presenting cellsQ34709049
Cancer immunotherapy using irradiated tumor cells secreting heat shock protein 70.Q35238502
Heat shock protein 70-associated peptides elicit specific cancer immunityQ36362368
Heat shock proteins: stress proteins with Janus-like properties in cancerQ37063489
Investigating receptors for extracellular heat shock proteinsQ39478462
Novel mechanism of Hsp70 chaperone-mediated prevention of polyglutamine aggregates in a cellular model of huntington diseaseQ39503540
Kinetics of chaperone activity of proteins Hsp70 and Hdj1 in human leukemia u-937 cells after preconditioning with thermal shock or compound u-133.Q39531040
Autologous Hsp70 immunization induces anti-tumor immunity and increases longevity and survival of tumor-bearing miceQ39869007
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cellsQ40408986
The cell surface-localized heat shock protein 70 epitope TKD induces migration and cytolytic activity selectively in human NK cells.Q40602103
Differential effect of acute and permanent heat shock protein 70 overexpression in tumor cells on lysability by cytotoxic T lymphocytesQ40606840
Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures.Q42910865
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress toleranceQ43751823
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanomaQ45855370
Antitumor effects of combined therapy of recombinant heat shock protein 70 and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanomaQ51813573
[The role of extracellular chaperone Hsp70 in creating antitumor immunity in rat rhabdomyosarcoma RA-2 model]Q82901378
P433issue3
P921main subjectmolecular chaperonesQ422496
immunotherapyQ1427096
P304page(s)391-396
P577publication date2012-12-12
P1433published inCell Stress & ChaperonesQ13458649
P1476titleHsp70 chaperone-based gel composition as a novel immunotherapeutic anti-tumor tool
P478volume18

Reverse relations

cites work (P2860)
Q26823593A central role for inducible heat-shock protein 70 in autoimmune vitiligo
Q55461040Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70.
Q38998531Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity
Q92156072Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells
Q39688737HSP70-based anti-cancer immunotherapy
Q33709375Neurotherapeutic activity of the recombinant heat shock protein Hsp70 in a model of focal cerebral ischemia in rats
Q33800747Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children
Q42096738Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma

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