Characterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain

scientific article published on June 1995

Characterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4826444
P698PubMed publication ID7791120

P50authorCatalina BetancurQ30668370
P2093author name stringW Rostène
D Gully
D Pélaprat
G Vela
M Canton
P2860cites workCloning and expression of a complementary DNA encoding a high affinity human neurotensin receptorQ24314254
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Two populations of neurotensin binding sites in murine brain: discrimination by the antihistamine levocabastine reveals markedly different radioautographic distributionQ28283120
Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brainQ28287754
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Interaction between neurotensin and dopamine in the brain. Morphofunctional and clinical evidenceQ34245314
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[3H]SR 48692, the first nonpeptide neurotensin antagonist radioligand: characterization of binding properties and evidence for distinct agonist and antagonist binding domains on the rat neurotensin receptorQ41348599
The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptorsQ41492785
In vivo and in vitro structure-activity studies with peptide and pseudopeptide neurotensin analogs suggest the existence of distinct central neurotensin receptor subtypesQ41496282
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The nonpeptide neurotensin antagonist, SR 48692, used as a tool to reveal putative neurotensin receptor subtypesQ41899918
Characterization of the binding of [3H]-(+/-)-L-364,718: a new potent, nonpeptide cholecystokinin antagonist radioligand selective for peripheral receptorsQ42205984
Blockade of neurotensin binding in the rat hypothalamus and of the central action of neurotensin on the hypothalamic-pituitary-adrenal axis with non-peptide receptor antagonists.Q42497176
Distribution of neurotensin binding sites in rat brain: a light microscopic radioautographic study using monoiodo [125I]Tyr3-neurotensinQ42517380
Mesencephalic dopaminergic neurons in primary cultures express functional neurotensin receptorsQ44463966
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Different subcellular localization of neurotensin-receptor and neurotensin-acceptor sites in the rat brain dopaminergic systemQ48097373
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SR 48692 inhibits neurotensin-induced [3H]dopamine release in rat striatal slices and mesencephalic culturesQ48158232
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Characterization and autoradiographic distribution of neurotensin binding sites in the human brainQ48428279
Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist.Q48643881
Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptorsQ48668858
Structure-antinociceptive activity of neurotensin and some novel analogues in the periaqueductal gray region of the brainstemQ48670799
Characterization and visualization of neurotensin binding to receptor sites in human brainQ48682917
The regional distribution and chromatographic characterisation of neurotensin-like immunoreactivity in the rat central nervous systemQ48959642
Neurotensin receptors are located on dopamine-containing neurones in rat midbrainQ49134437
Effects of neurotensin on dopamine release and metabolism in the rat striatum and nucleus accumbens: cross-validation using in vivo voltammetry and microdialysisQ49158261
The Neurobiology of Neurotensin. Proceedings of 2nd International Conference on Neurotensin. Palm Beach, Florida, July 8, 1991Q67888293
Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitroQ69375836
Heterogeneity of [3H]neurotensin bindings: studies with dynorphin, L-156,903 and levocabastineQ69929632
Rat cardiac muscarinic receptors. I. Effects of guanine nucleotides on high- and low-affinity binding sitesQ70434547
Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptorQ72420075
Neurotensin modulates dopamine neurotransmission at several levels along brain dopaminergic pathwaysQ84305745
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1450-1458
P577publication date1995-06-01
P1433published inJournal of Pharmacology and Experimental TherapeuticsQ1500272
P1476titleCharacterization and distribution of binding sites for a new neurotensin receptor antagonist ligand, [3H]SR 48692, in the guinea pig brain
P478volume273

Reverse relations

Q48407590The striatal neurotensin receptor modulates striatal and pallidal glutamate and GABA release: functional evidence for a pallidal glutamate-GABA interaction via the pallidal-subthalamic nucleus loop.cites workP2860

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