Mitochondrial electron transport and glycolysis are coupled in articular cartilage

scientific article published on 16 January 2012

Mitochondrial electron transport and glycolysis are coupled in articular cartilage is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JOCA.2012.01.003
P932PMC publication ID3634328
P698PubMed publication ID22305999
P5875ResearchGate publication ID221806591

P2093author name stringJ A Martin
A Martini
T O McKinley
A Molinari
J A Buckwalter
W Morgan
W Ramalingam
P2860cites workTonic activation of hypoxia-inducible factor 1alpha in avascular articular cartilage and implications for metabolic homeostasisQ46732459
Validation of a rapid, large-scale assay to quantify ATP concentration in spermatozoaQ46858805
Mitochondrial dysfunction in osteoarthritisQ47739967
Calcium signaling leads to mitochondrial depolarization in impact-induced chondrocyte death in equine articular cartilage explants.Q50467634
The role of mitochondrial reactive oxygen species in pH regulation in articular chondrocytes.Q50696729
Cyclic strain and motion control produce opposite oxidative responses in two human endothelial cell types.Q51062918
Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes.Q51785699
Mitochondrial biogenesis in rabbit articular chondrocytes transferred to cultureQ68002888
Synovial oxygen partial pressure after experimental microtraumatic joint affectionQ68067186
Bovine articular chondrocyte function in vitro depends upon oxygen tensionQ74247481
Endothelial cell mechanosensitivity. Focus on "Cyclic strain and motion control produce opposite oxidative responses in two human endothelial cell types"Q79952911
How mitochondria produce reactive oxygen speciesQ24643882
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondriaQ28610852
Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic propertiesQ31621261
Morphometry of cytoplasmic components of mammalian articular chondrocytes and corneal keratocytes: species and zonal variations of mitochondria in relation to nutritionQ34015233
Cell biology of osteoarthritis: the chondrocyte's response to injuryQ34439709
The role of reactive oxygen species in homeostasis and degradation of cartilageQ34537354
Joint injury, repair, and remodeling: roles in post-traumatic osteoarthritisQ35825648
Oxygen and reactive oxygen species in cartilage degradation: friends or foes?Q36152437
Resting chondrocytes in culture survive without growth factors, but are sensitive to toxic oxygen metabolitesQ36223252
Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organismQ36231438
Invited review: the mitochondrion in osteoarthritisQ36239810
Generation of superoxide by the mitochondrial Complex I.Q36469867
Cell death and apoptosis in osteoarthritic cartilageQ36737798
MitoQ--a mitochondria-targeted antioxidant.Q36887240
Rotenone prevents impact-induced chondrocyte deathQ36917896
The potential role of vascular endothelial growth factor (VEGF) in cartilage: how the angiogenic factor could be involved in the pathogenesis of osteoarthritis?Q36975196
Oxidant conditioning protects cartilage from mechanically induced damageQ37003698
Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalanceQ37267822
N-acetylcysteine inhibits post-impact chondrocyte death in osteochondral explantsQ37272591
Mitochondria and reactive oxygen speciesQ37475734
Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.Q37608294
Evidence for a negative Pasteur effect in articular cartilageQ39439118
Functional replacement of oxygen by other oxidants in articular cartilageQ39637748
Mode of action of natural insecticidesQ39982472
Antibiotic inhibitors of mitochondrial energy transferQ40295568
Efficacy of 2-halogen substituted D-glucose analogs in blocking glycolysis and killing "hypoxic tumor cells".Q40300814
A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha.Q40429133
Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralizationQ40867589
Both superficial and deep zone articular chondrocyte subpopulations exhibit the Crabtree effect but have different basal oxygen consumption rates.Q42467047
Basic cell metabolism of articular cartilage. Manometric studiesQ42469120
Damage control mechanisms in articular cartilage: the role of the insulin-like growth factor I axisQ42491727
Reactive oxygen species downregulate the expression of pro-inflammatory genes by human chondrocytesQ44446440
Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigsQ44839348
Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransductionQ44848147
Synovitis causes hypoxia and acidity in synovial fluid and subchondral boneQ46626075
P433issue4
P304page(s)323-329
P577publication date2012-01-16
P1433published inOsteoarthritis and CartilageQ7107605
P1476titleMitochondrial electron transport and glycolysis are coupled in articular cartilage
P478volume20

Reverse relations

cites work (P2860)
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Q31152928Combining Targeted Metabolomic Data with a Model of Glucose Metabolism: Toward Progress in Chondrocyte Mechanotransduction.
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Q52584267Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis.
Q50158090Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage
Q52715515Effects of Artesunate on chondrocyte proliferation, apoptosis and autophagy through the PI3K/AKT/mTOR signaling pathway in rat models with rheumatoid arthritis.
Q48020850Enhancement of Energy Production of the Intervertebral Disc by the Implantation of Polyurethane Mass Transfer Devices
Q26777620Inflammation and intracellular metabolism: new targets in OA
Q38632508Injurious Loading of Articular Cartilage Compromises Chondrocyte Respiratory Function
Q46915803Involvement of mitochondrial dysfunction and ER-stress in the physiopathology of equine osteochondritis dissecans (OCD).
Q36917888Mechanical stress and ATP synthesis are coupled by mitochondrial oxidants in articular cartilage
Q42176724Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor γ coactivator 1α
Q35257654Mitochondrial respiration and redox coupling in articular chondrocytes
Q42207792Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system
Q35128583Peroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase
Q27314567Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ
Q91995445Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases
Q39023669Respiratory gas exchange as a new aid to monitor acidosis in endotoxemic rats: relationship to metabolic fuel substrates and thermometabolic responses.
Q30573235Strain-dependent oxidant release in articular cartilage originates from mitochondria
Q50045905Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis.
Q38734393The role of metabolism in the pathogenesis of osteoarthritis

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