| P2093 | author name string | Herbert Y Lin | |
| | Robert E Fleming | |
| | Qi Feng | |
| | Delphine Meynard | |
| | Jodie L Babitt | |
| | Adam Odhiambo | |
| | Elena Corradini | |
| | Mary C Migas | |
| | Robert S Britton | |
| | Molly Rozier | |
| P2860 | cites work | Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family | Q22010394 |
| | Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization | Q24310115 |
| | Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload | Q24312272 |
| | HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron | Q24312763 |
| | Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression | Q24316099 |
| | A mouse model of juvenile hemochromatosis | Q24532268 |
| | Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis | Q24533580 |
| | Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6 | Q24550935 |
| | IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin | Q24568204 |
| | ER stress controls iron metabolism through induction of hepcidin | Q24630714 |
| | Pathophysiology of hereditary hemochromatosis | Q24654441 |
| | Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance | Q24682390 |
| | The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin | Q28115763 |
| | Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter | Q28208212 |
| | Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin | Q28260085 |
| | HFE gene knockout produces mouse model of hereditary hemochromatosis | Q28263309 |
| | Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver | Q28506594 |
| | Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6 | Q28507491 |
| | Lack of the bone morphogenetic protein BMP6 induces massive iron overload | Q28510138 |
| | Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing | Q28510853 |
| | A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression | Q28590840 |
| | Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR | Q29400573 |
| | Iron homeostasis: fitting the puzzle pieces together | Q33345413 |
| | Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice | Q33806074 |
| | Regulation of hepcidin transcription by interleukin-1 and interleukin-6. | Q33836338 |
| | Mass spectrometry analysis of hepcidin peptides in experimental mouse models | Q33847518 |
| | The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. | Q33901224 |
| | Hereditary hemochromatosis--a new look at an old disease | Q34324340 |
| | Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression | Q34658174 |
| | Id: a target of BMP signaling | Q34895468 |
| | The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression | Q36539421 |
| | Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells | Q37262477 |
| | Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis | Q37376502 |
| | Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis | Q38516501 |
| | SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression | Q39757901 |
| | Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. | Q39881846 |
| | BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism | Q41871982 |
| | Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation. | Q42140428 |
| | Iron overload induces BMP6 expression in the liver but not in the duodenum. | Q42586767 |
| | Altered hepatic BMP signaling pathway in human HFE hemochromatosis | Q42596912 |
| | Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis | Q44409470 |
| | Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis | Q46619033 |
| | Hepcidin is decreased in TFR2 hemochromatosis | Q46624831 |
| | BMP6 orchestrates iron metabolism. | Q51741097 |
| | Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. | Q52549517 |
| | STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo. | Q52576434 |
| | Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues. | Q54440169 |
| | Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. | Q54459192 |
| | BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression. | Q54472480 |
| | Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis | Q59512864 |
| | Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes | Q61638656 |
| | Iron-Induced Expression of Bone Morphogenic Protein 6 in Intestinal Cells Is the Main Regulator of Hepatic Hepcidin Expression In Vivo | Q61829377 |
| | Decreased liver hepcidin expression in the Hfe knockout mouse | Q78840314 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1907-1914 | |
| P577 | publication date | 2011-07-13 | |
| P1433 | published in | Gastroenterology | Q4039279 |
| P1476 | title | Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe | |
| P478 | volume | 141 | |