Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein

scientific article published on November 1990

Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID248631
P698PubMed publication ID2145446

P50authorMax EssexQ6794729
P2093author name stringM Matsuda
T H Lee
X F Yu
P2860cites workHuman immunodeficiency virus vpr product is a virion-associated regulatory proteinQ24649600
A novel human immunodeficiency virus type 1 protein, tev, shares sequences with tat, env, and rev proteinsQ28246228
The role of mononuclear phagocytes in HTLV-III/LAV infectionQ29618676
The N-terminal region of the human immunodeficiency virus envelope glycoprotein gp120 contains potential binding sites for CD4.Q33579510
Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genomeQ33649232
Human immunodeficiency virus can infect CD4-negative human fibroblastoid cellsQ33868217
A tripartite HIV-1 tat-env-rev fusion proteinQ33918908
Genome organization and transactivation of the human immunodeficiency virus type 2.Q34048704
A second post-transcriptional trans-activator gene required for HTLV-III replicationQ34162178
Identification of a protein encoded by the vpu gene of HIV-1.Q34163678
Identification of HIV-1 vpr product and functionQ34168026
HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.Q34186306
Structure of simian immunodeficiency virus regulatory genesQ34284560
Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species.Q34314770
Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.Q34564460
Infection of monocyte/macrophages by human T lymphotropic virus type III.Q34579117
Human immunodeficiency virus can productively infect cultured human glial cellsQ34625813
Human T-cell leukemia virus-associated membrane antigens: identity of the major antigens recognized after virus infectionQ36263370
Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retrovirusesQ36470925
Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM).Q36800949
CD4-independent, productive infection of a neuronal cell line by human immunodeficiency virus type 1Q36802755
Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells.Q36829615
Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody productionQ36870842
Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC.Q36872683
Functional comparison of transactivation by simian immunodeficiency virus from rhesus macaques and human immunodeficiency virus type 1.Q36873530
Mutational analysis of the human immunodeficiency virus vpr open reading frame.Q40116997
A naturally immunogenic virion-associated protein specific for HIV-2 and SIV.Q42649286
The human immunodeficiency virus type 2 (HIV-2) contains a novel gene encoding a 16 kD protein associated with mature virionsQ42653163
A novel gene of HIV-1, vpu, and its 16-kilodalton productQ42656133
Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2.Q42658314
Human immunodeficiency virus: the eighth geneQ45831425
Sequence of simian immunodeficiency virus from African green monkey, a new member of the HIV/SIV groupQ45832109
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).Q45838520
A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patientsQ46065811
Cloning of HTLV-4 and its relation to simian and human immunodeficiency virusesQ46796894
Identification of HTLV-III/LAV sor gene product and detection of antibodies in human seraQ48367084
Replicative and cytopathic potential of HTLV-III/LAV with sor gene deletionsQ48367096
A new HTLV-III/LAV protein encoded by a gene found in cytopathic retrovirusesQ48367108
Infection of chimpanzees by human T-lymphotropic retroviruses in brain and other tissues from AIDS patientsQ48536859
Transmission of HTLV-III Infection from Human Plasma to Chimpanzees: An Animal Model for AIDSQ52849903
Antibodies to simian T-lymphotropic retrovirus type III in African green monkeys and recognition of STLV-III viral proteins by AIDS and related sera.Q53899622
Infection and replication of HIV-1 in purified progenitor cells of normal human bone marrowQ69045908
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectvirionQ1757347
Simian immunodeficiency virusQ1890246
P304page(s)5688-5693
P577publication date1990-11-01
P1433published inJournal of VirologyQ1251128
P1476titleOpen reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein
P478volume64

Reverse relations

cites work (P2860)
Q33824939A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)
Q40428153A defective HIV-1 vector for gene transfer to human lymphocytes
Q34501320A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects.
Q36255858Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways
Q24671784DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest
Q34467563Depletion of Wee-1 kinase is necessary for both human immunodeficiency virus type 1 Vpr- and gamma irradiation-induced apoptosis
Q36484010Evidence for Vpr-dependent HIV-1 replication in human CD4+ CEM.NKR T-cells
Q33938392Evolution of the primate lentiviruses: evidence from vpx and vpr
Q35832979Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.
Q35846506Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr
Q64101946Functional proteomic atlas of HIV infection in primary human CD4+ T cells
Q39549465Highly purified human immunodeficiency virus type 1 reveals a virtual absence of Vif in virions.
Q39550551Human immunodeficiency virus type 1 (HIV-1) Vpr functions as an immediate-early protein during HIV-1 infection
Q33852465Human immunodeficiency virus type 1 Vif protein is packaged into the nucleoprotein complex through an interaction with viral genomic RNA.
Q38609782Human immunodeficiency virus type 1 Vpr binds to the N lobe of the Wee1 kinase domain and enhances kinase activity for CDC2
Q39880367Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest
Q37356043Human immunodeficiency virus type 1 Vpr modulates cellular expression of UNG2 via a negative transcriptional effect
Q33811857Human immunodeficiency virus type 1 Vpr protein is incorporated into the virion in significantly smaller amounts than gag and is phosphorylated in infected cells
Q35077587Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells
Q36654319Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions
Q33801078Human immunodeficiency virus type 1 vpr induces apoptosis through caspase activation
Q36770468Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus.
Q36655127Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.
Q41039185Increased levels of Wee-1 kinase in G(2) are necessary for Vpr- and gamma irradiation-induced G(2) arrest
Q38716281Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly
Q35860937Inhibition of human and simian immunodeficiency virus protease function by targeting Vpx-protease-mutant fusion protein into viral particles
Q36398981Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages
Q39820667Molecular biology and pathogenesis of animal lentivirus infections.
Q35850945Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.
Q24684633Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr
Q36694013Mutational analysis of conserved N-linked glycosylation sites of human immunodeficiency virus type 1 gp41
Q70201773New nucleotide sequence data on the EMBL File Server
Q35890940Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.
Q35837777Progression to AIDS in the absence of a gene for vpr or vpx.
Q33587139Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage
Q35851550Regulatory genes of simian immunodeficiency viruses from west African green monkeys (Cercopithecus aethiops sabaeus)
Q36630330Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles
Q35882940Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1
Q35839628Targeting foreign proteins to human immunodeficiency virus particles via fusion with Vpr and Vpx.
Q33937603The C terminus of human immunodeficiency virus type 1 matrix protein is involved in early steps of the virus life cycle
Q39685690The first HxRxG motif in simian immunodeficiency virus mac239 Vpr is crucial for G(2)/M cell cycle arrest
Q36700852The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions
Q35838540The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles
Q36797922The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage
Q24673660Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest
Q43156923Viral determinants of integration site preferences of simian immunodeficiency virus-based vectors
Q35859146Vpr-induced cell cycle arrest is conserved among primate lentiviruses.
Q36650496Vpx of simian immunodeficiency virus is localized primarily outside the virus core in mature virions.
Q35844498vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys

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