Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity

scientific article published on 9 May 2012

Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11357-012-9408-8
P932PMC publication ID3636412
P698PubMed publication ID22569962
P5875ResearchGate publication ID224925874

P50authorGiuseppe RemuzziQ16561003
Daniela MariQ30093174
Hiromi RakugiQ35703947
Ariela BenigniQ41002318
Paraskevas IatropoulosQ55692961
Marina NorisQ57561179
Silvia OrisioQ114428712
Marta TodeschiniQ114428733
P2093author name stringNobuyoshi Hirose
Yasumichi Arai
Kei Kamide
Enyu Imai
Yasuyuki Gondo
Davide Castaldi
Giulia Ogliari
P2860cites workMitochondrial DNA haplogroup D4a is a marker for extreme longevity in JapanQ21562568
Association of FOXO3A variation with human longevity confirmed in German centenariansQ24646035
FOXO3A genotype is strongly associated with human longevityQ24647408
Disruption of the Ang II type 1 receptor promotes longevity in miceQ24647615
Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypesQ24678210
Haploview: analysis and visualization of LD and haplotype mapsQ27860955
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithmQ29547194
Prediction of deleterious human allelesQ29614367
The structure and function of G-protein-coupled receptorsQ29616792
Increased nitric oxide formation in recurrent thrombotic microangiopathies: a possible mediator of microvascular injuryQ33495922
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.Q33593068
Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressureQ33907930
Cardiovascular status of carriers of the apolipoprotein A-I(Milano) mutant: the Limone sul Garda studyQ33942742
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevityQ34017801
Interplay between miR-155, AT1R A1166C polymorphism, and AT1R expression in young untreated hypertensives.Q34145150
Angiotensin II revisited: new roles in inflammation, immunology and agingQ36039299
From mitochondria to disease: role of the renin-angiotensin systemQ36929305
Angiotensin II type 1 receptor polymorphisms and susceptibility to hypertension: a HuGE reviewQ37194034
Signaling mechanisms of angiotensin II in regulating vascular senescenceQ37375272
Accounting for human polymorphisms predicted to affect protein functionQ39753550
Angiotensin type 1 receptor expression and interleukin-8 production in polymorphonuclear leukocytes of patients with peripheral arterial disease.Q43276263
Altered signal pathway in angiotensin II-stimulated neutrophils of patients with hypercholesterolaemiaQ44009047
Oxidative stress is a critical mediator of the angiotensin II signal in human neutrophils: involvement of mitogen-activated protein kinase, calcineurin, and the transcription factor NF-kappaB.Q44381152
Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers effectively and directly potentiate superoxide scavenging by polymorphonuclear leukocytes from patients with type 2 diabetes mellitusQ46491411
Prolonged statin-associated reduction in neutrophil reactive oxygen species and angiotensin II type 1 receptor expression: 1-year follow-upQ46663053
Angiotensin II type 1 receptor expression on human leukocyte subsets: a flow cytometric and RT-PCR study.Q46986151
Characterization of polymorphisms in the promoter of the human angiotensin II subtype 1 (AT1) receptor gene.Q52973147
Apolipoprotein E genotype and the rate of decline in probable Alzheimer disease.Q53323163
Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms of angiotensin II-induced inflammation.Q53568433
Angiotensin II type 1 receptor expression in polymorphonuclear leukocytes from high-risk subjects: changes after treatment with simvastatin.Q54250247
Peripheral donor leukocytes prolong survival of rat renal allograftsQ57703842
Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophilsQ61880928
Role of oxygen-derived free radicals in acute angiotensin II--induced hypertensive vascular disease in the ratQ68715371
Interactions between conserved residues in transmembrane helices 2 and 7 during angiotensin AT1 receptor activationQ79440699
Angiotensin II type 1 receptor gene polymorphism predicts development of hypertension and metabolic syndromeQ82678869
Association of angiotensin II type 1-receptor gene polymorphisms with the risk of developing hypertension in Mexican individualsQ84776097
P433issue3
P304page(s)993-1005
P577publication date2012-05-09
P1433published inAgeQ4691832
P1476titleVariations of the angiotensin II type 1 receptor gene are associated with extreme human longevity
P478volume35

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Q27309126Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span
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