Inositol trisphosphate levels in cells expressing wild-type and mutant polyomavirus middle T antigens: evidence for activation of phospholipase C via activation of pp60c-src

scientific article published on January 1990

Inositol trisphosphate levels in cells expressing wild-type and mutant polyomavirus middle T antigens: evidence for activation of phospholipase C via activation of pp60c-src is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID249057
P698PubMed publication ID2152807

P2093author name stringT L Benjamin
C E Riney
F R Gorga
P2860cites workThe polyphosphoinositide phosphodiesterase of erythrocyte membranesQ24530881
Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphateQ28280837
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformationQ28286516
Role of phosphatidylinositol kinase in PDGF receptor signal transductionQ28645684
Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoterQ29614259
Phosphorus assay in column chromatographyQ29614973
The role of protein kinase C in cell surface signal transduction and tumour promotionQ29618532
Host range mutants of polyoma virusQ33703831
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylationQ33931404
The complex of polyoma virus middle-T antigen and pp60c-srcQ33939386
Localization of gene functions in polyoma virus DNAQ35037597
Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A-431 cellsQ35103454
5-Bromo-2'-deoxyuridine potentiation of transformation of rat-embryo cells induced in vitro by 3-methylcholanthrene: induction of rat leukemia virus gs antigen in transformed cellsQ35110792
Phosphatidylinositol metabolism and polyoma-mediated transformationQ35607272
Dissociation of inositol trisphosphate from diacylglycerol production in Rous sarcoma virus-transformed fibroblastsQ36220044
Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigenQ36253069
Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesisQ36259155
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerolQ36266572
Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformationQ36298676
Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cellsQ36769553
Regulation of cellular phenotype and expression of polyomavirus middle T antigen in rat fibroblastsQ36893737
Structural and functional modification of pp60c-src associated with polyoma middle tumor antigen from infected or transformed cellsQ36894563
Middle tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with pp60c-srcQ36903837
Evidence for involvement of guanine nucleotide-binding regulatory proteins in the activation of phospholipases by hormonesQ39224213
Inositol phosphates: proliferation, metabolism and functionQ39472079
Inositol trisphosphate and diacylglycerol: two interacting second messengersQ39664919
Changes in phosphatidylinositol metabolism correlated to growth state of normal and Rous sarcoma virus-transformed Japanese quail cellsQ40083504
Cellular alterations dependent upon the polyoma virus hr-t function: Separation of mitogenic from transforming capacitiesQ40170606
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activityQ42806818
Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domainQ42808327
Polyoma virus transforming protein associates with the product of the c-src cellular geneQ45798405
Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformationQ45807428
Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesisQ46587019
Phosphatidylinositol 3-phosphate is present in normal and transformed fibroblasts and is resistant to hydrolysis by bovine brain phospholipase C II.Q53515187
Altered signal transduction in erbB-transformed cells. Implication of enhanced inositol phospholipid metabolism in erbB-induced transformation.Q53529917
A guanine nucleotide-dependent phosphatidylinositol 4,5-diphosphate phospholipase C in cells transformed by the v-fms and v-fes oncogenes.Q53537372
An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinaseQ69001665
P433issue1
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)105-112
P577publication date1990-01-01
P1433published inJournal of VirologyQ1251128
P1476titleInositol trisphosphate levels in cells expressing wild-type and mutant polyomavirus middle T antigens: evidence for activation of phospholipase C via activation of pp60c-src
P478volume64

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cites work (P2860)
Q33783341Evidence of a role for phosphatidylinositol 3-kinase activation in the blocking of apoptosis by polyomavirus middle T antigen.
Q35000523Lessons in signaling and tumorigenesis from polyomavirus middle T antigen
Q41062169Mammary tumors induced by polyomavirus
Q30195440Mutations in the SH3 domain of the src oncogene which decrease association of phosphatidylinositol 3'-kinase activity with pp60v-src and alter cellular morphology
Q33948870Natural biology of polyomavirus middle T antigen
Q40110300Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen
Q30441810Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene
Q40144028The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation
Q36298429Tumor induction by a transformation-defective polyoma virus mutant blocked in signaling through Shc
Q39880346pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence
Q42635902ras transformation is associated with decreased expression of the brm/SNF2alpha ATPase from the mammalian SWI-SNF complex.

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