Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma

scientific article published on 29 April 2013

Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2013.00054
P932PMC publication ID3638148
P698PubMed publication ID23641215
P5875ResearchGate publication ID236615222

P2093author name stringSanjay Kumar
David J Behm
Kelly M Mahar
Robert B Noble
Steven F Russ
Alison Portnoy
John P Throup
P2860cites workHuman urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14Q22010575
Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1Q24674639
Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failureQ28177421
GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivoQ34233981
The addition of long-acting beta-agonists to inhaled corticosteroids in asthmaQ37806573
Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissuesQ39967100
Inhibitory effects of putative peptidic urotensin-II receptor antagonists on urotensin-II-induced contraction of cat isolated respiratory smooth muscleQ40405628
Differential vasoconstrictor activity of human urotensin-II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkeyQ42059806
Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat.Q43264408
Human urotensin-II is a potent spasmogen of primate airway smooth muscleQ43264553
The signal transduction pathway in the proliferation of airway smooth muscle cells induced by urotensin II.Q44735245
The upregulation of endothelial nitric oxide synthase and urotensin-II is associated with pulmonary hypertension and vascular diseases in rats produced by aortocaval shuntingQ47888360
Urotensin upregulates transforming growth factor-β1 expression of asthma airway through ERK-dependent pathway.Q54534462
Guide to Receptors and Channels (GRAC), 4th EditionQ56639335
Effect of chronic hypoxia on contents of urotensin II and its functional receptors in rat myocardiumQ77611267
[Changes in urotensin-II expression in airway remodelling in asthmatic rats]Q84103330
P304page(s)54
P577publication date2013-04-29
P1433published inFrontiers in PharmacologyQ2681208
P1476titleEffects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma
P478volume4

Reverse relations

cites work (P2860)
Q90234227Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after Lipopolysaccharide induced lung inflammation
Q98629310Multi-organ transcriptomic landscape of Ambystoma velasci metamorphosis

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