Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse

scientific article published on 3 June 2008

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2007-11-126227
P932PMC publication ID2515110
P698PubMed publication ID18523155
P5875ResearchGate publication ID51399512

P50authorJean-Pierre J IssaQ55459879
Hagop KantarjianQ60394812
Carlos B Bueso-RamosQ90223571
Woonbok ChungQ92086738
Kimie KondoQ117223256
P2093author name stringLi Zhang
Lanlan Shen
Jaroslav Jelinek
Rong He
Marcos R H Estécio
Heike Kroeger
P2860cites workHigh sensitivity mapping of methylated cytosinesQ24630600
Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sitesQ28187720
Cadherin-13, a mediator of calcium-dependent cell-cell adhesion, is silenced by methylation in chronic myeloid leukemia and correlates with pretreatment risk profile and cytogenetic response to interferon alfaQ28191349
Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumorsQ28215348
The epigenomics of cancerQ28289975
Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5' CpG island methylation.Q30322368
Aberrant DNA methylation of p57KIP2 identifies a cell-cycle regulatory pathway with prognostic impact in adult acute lymphocytic leukemiaQ33186068
Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promotersQ33304220
Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancersQ34310451
Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemiaQ34396332
Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosisQ34455183
Silencing of bidirectional promoters by DNA methylation in tumorigenesisQ34527442
Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemiaQ34553286
High-throughput methylation profiling by MCA coupled to CpG island microarrayQ36004673
Genetics of myeloid malignancies: pathogenetic and clinical implicationsQ36254578
Epigenetic changes in solid and hematopoietic tumors.Q36279348
Reduced BRCA1 expression due to promoter hypermethylation in therapy-related acute myeloid leukaemiaQ36612343
Oligonucleotide inhibitors of Taq DNA polymerase facilitate detection of low copy number targets by PCR.Q36836246
The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemiaQ38305661
Methylation silencing of the Apaf-1 gene in acute leukemiaQ40406002
Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours.Q40448817
Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylateQ40508930
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elementsQ40587967
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplificationQ40951949
The estrogen receptor CpG island is methylated in most hematopoietic neoplasms.Q41223399
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.Q41228119
JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemiaQ42182981
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatmentQ44155422
Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells.Q44922040
Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemiaQ46758045
Methylation profiling in acute myeloid leukemia.Q53729917
Promoter hypermethylation of the retinoic acid receptor beta2 gene is frequent in acute myeloid leukaemia and associated with the presence of CBFbeta-MYH11 fusion transcripts.Q54605238
RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.Q55043439
Changes in DNA Methylation Patterns in Subjects Exposed to Low-Dose BenzeneQ57208389
Methylation and prognosis: of molecular clocks and hypermethylator phenotypesQ73796635
CpG island methylator phenotype redefines the prognostic effect of t(12;21) in childhood acute lymphoblastic leukemiaQ80129003
CpG island methylator phenotype in cancerQ81080870
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
CpG islandQ1138360
acute myeloid leukemiaQ264118
P304page(s)1366-1373
P577publication date2008-06-03
P1433published inBloodQ885070
P1476titleAberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse
P478volume112