| scholarly article | Q13442814 |
| P50 | author | Vincent Poitout | Q43213452 |
| Melkam Kebede | Q42966533 | ||
| Thierry Alquier | Q43185232 | ||
| P2093 | author name string | Martin G Latour | |
| Caroline Tremblay | |||
| Meriem Semache | |||
| P2860 | cites work | Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice | Q43733884 |
| Insufficient islet compensation to insulin resistance vs. reduced glucose effectiveness in glucose-intolerant mice | Q44129319 | ||
| The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse | Q46626401 | ||
| Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. | Q54590591 | ||
| The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets. | Q54611520 | ||
| The free fatty acid receptor GPR40 generates excitement in pancreatic beta-cells | Q82286003 | ||
| The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids | Q27863758 | ||
| A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs | Q27863760 | ||
| Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. | Q27863762 | ||
| Role of GPR40 in fatty acid action on the beta cell line INS-1E. | Q27863895 | ||
| Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40. | Q27864132 | ||
| GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. | Q27865189 | ||
| The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing | Q28269458 | ||
| Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic beta cells and implications for insulin secretion | Q28301027 | ||
| Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120 | Q28507400 | ||
| Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin gene expression and Pdx-1 binding in islets. | Q28577842 | ||
| The ins and outs of fatty acids on the pancreatic beta cell | Q35162533 | ||
| Fatty acid receptors as new therapeutic targets for diabetes | Q36804437 | ||
| Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice | Q36807640 | ||
| Hormonal Control of Ketogenesis | Q39789738 | ||
| Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules | Q40279477 | ||
| GPR40, a free fatty acid receptor on pancreatic beta cells, regulates insulin secretion | Q40363831 | ||
| Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion. | Q40393287 | ||
| Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic beta-cells and mediates fatty acid effects on insulin secretion. | Q40464486 | ||
| Starvation-induced changes of palmitate metabolism and insulin secretion in isolated rat islets stimulated by glucose | Q41832703 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | fatty acid | Q61476 |
| preproinsulin | Q7240673 | ||
| P304 | page(s) | 2432-2437 | |
| P577 | publication date | 2008-06-16 | |
| P1433 | published in | Diabetes | Q895262 |
| P1476 | title | The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding | |
| P478 | volume | 57 |
| Q49549662 | 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1. |
| Q47123031 | A novel free fatty acid receptor 1 (GPR40/FFAR1) agonist, MR1704, enhances glucose-dependent insulin secretion and improves glucose homeostasis in rats. |
| Q34441309 | A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents |
| Q38123792 | Activation of GPR40 as a therapeutic target for the treatment of type 2 diabetes |
| Q34076033 | Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion |
| Q46260467 | Considerations and guidelines for mouse metabolic phenotyping in diabetes research. |
| Q83532321 | Could FFAR1 assist insulin secretion in type 2 diabetes? |
| Q83358851 | Current literature in diabetes |
| Q28533802 | DC260126: a small-molecule antagonist of GPR40 that protects against pancreatic β-Cells dysfunction in db/db mice |
| Q34687550 | Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice |
| Q37400740 | Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets |
| Q42516950 | Deletion of Protein Kinase D1 in Pancreatic Beta Cells Impairs Insulin Secretion in High-Fat Fed Mice |
| Q37810292 | Diabetes area participation analysis: a review of companies and targets described in the 2008 - 2010 patent literature |
| Q54077093 | Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment. |
| Q36810761 | Disruption of the sugar-sensing receptor T1R2 attenuates metabolic derangements associated with diet-induced obesity |
| Q42174959 | Drug discovery opportunities and challenges at g protein coupled receptors for long chain free Fatty acids |
| Q37237145 | Drugs or diet?--Developing novel therapeutic strategies targeting the free fatty acid family of GPCRs |
| Q36113667 | Elevated nocturnal NEFA are an early signal for hyperinsulinaemic compensation during diet-induced insulin resistance in dogs. |
| Q38067511 | Endogenous metabolites as ligands for G protein-coupled receptors modulating risk factors for metabolic and cardiovascular disease |
| Q36796096 | Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes |
| Q38160275 | Fasiglifam as a new potential treatment option for patients with type 2 diabetes |
| Q35687964 | Fish Oil Accelerates Diet-Induced Entrainment of the Mouse Peripheral Clock via GPR120. |
| Q38943148 | For Better or Worse: FFAR1 and FFAR4 Signaling in Cancer and Diabetes |
| Q36327956 | Free fatty acid receptors: emerging targets for treatment of diabetes and its complications |
| Q42708811 | G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1. |
| Q38715488 | G protein-coupled receptors as targets for anti-diabetic therapeutics |
| Q38025858 | G protein-coupled receptors for energy metabolites as new therapeutic targets |
| Q38688833 | G protein-coupled receptors: signalling and regulation by lipid agonists for improved glucose homoeostasis. |
| Q38325894 | GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit. |
| Q36560325 | GPR40 modulators: new kid on the block |
| Q38809425 | GPR40, a free fatty acid receptor, differentially impacts osteoblast behavior depending on differentiation stage and environment |
| Q39690535 | GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes |
| Q37163504 | GPR40: good cop, bad cop? |
| Q39105825 | GW9508, a free fatty acid receptor agonist, specifically induces cell death in bone resorbing precursor cells through increased oxidative stress from mitochondrial origin |
| Q33665283 | Glucolipotoxicity of the pancreatic beta cell. |
| Q24629432 | Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1 |
| Q37911549 | Glucose-dependent insulinotropic polypeptide: from pathophysiology to therapeutic opportunities in obesity-associated disorders |
| Q36335625 | Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor |
| Q33718447 | Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice |
| Q35227161 | Inhibition of Id1 augments insulin secretion and protects against high-fat diet-induced glucose intolerance |
| Q30426407 | Investigational anti-hyperglycemic agents: the future of type 2 diabetes therapy? |
| Q54116722 | Is the effect of high fat diet on lipid and carbohydrate metabolism related to inflammation? |
| Q37443837 | Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes |
| Q39016250 | Key Questions for Translation of FFA Receptors: From Pharmacology to Medicines |
| Q36943727 | Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease |
| Q43462035 | Lack of GPR40/FFAR1 does not induce diabetes even under insulin resistance condition |
| Q33930824 | Lipid receptors and islet function: therapeutic implications? |
| Q51345722 | Lipid stimulation of fatty acid sensors in the human duodenum: relationship with gastrointestinal hormones, BMI and diet. |
| Q26777794 | Membrane Potential and Calcium Dynamics in Beta Cells from Mouse Pancreas Tissue Slices: Theory, Experimentation, and Analysis |
| Q38107811 | Minireview: The effects of species ortholog and SNP variation on receptors for free fatty acids. |
| Q37702790 | Molecular mechanisms underlying nutrient detection by incretin-secreting cells |
| Q37253051 | Oleic acid and peanut oil high in oleic acid reverse the inhibitory effect of insulin production of the inflammatory cytokine TNF-alpha both in vitro and in vivo systems |
| Q38503042 | Oral and intestinal sweet and fat tasting: impact of receptor polymorphisms and dietary modulation for metabolic disease |
| Q27865234 | Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice |
| Q64248835 | Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells |
| Q39013784 | Polymorphic Variation in FFA Receptors: Functions and Consequences. |
| Q37481309 | Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): an emerging target for type 2 diabetes |
| Q36560412 | Randomized, double-blind, dose-ranging study of TAK-875, a novel GPR40 agonist, in Japanese patients with inadequately controlled type 2 diabetes |
| Q36772416 | Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. |
| Q89442826 | Role of Short Chain Fatty Acid Receptors in Intestinal Physiology and Pathophysiology |
| Q39158059 | Structure-Activity Study of Dihydrocinnamic Acids and Discovery of the Potent FFA1 (GPR40) Agonist TUG-469. |
| Q33610629 | Sweet taste receptors regulate basal insulin secretion and contribute to compensatory insulin hypersecretion during the development of diabetes in male mice. |
| Q42954535 | TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats |
| Q36165684 | Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases |
| Q38259563 | The G-Protein-Coupled Long-Chain Fatty Acid Receptor GPR40 and Glucose Metabolism |
| Q36477035 | The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin |
| Q47654520 | The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. |
| Q38799812 | The Role and Future of FFA1 as a Therapeutic Target |
| Q27865233 | The action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1 |
| Q42141283 | Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine. |
| Q38855180 | β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1. |
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