Tcf21 regulates the specification and maturation of proepicardial cells

scientific article published on May 2013

Tcf21 regulates the specification and maturation of proepicardial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/DEV.093385
P932PMC publication ID3653561
P698PubMed publication ID23637334
P5875ResearchGate publication ID236603746

P2093author name stringIleana M Cristea
Frank L Conlon
Lauren M Kuchenbrod
Panna Tandon
Yana V Miteva
P2860cites workYAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesisQ22009123
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A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3Q24312935
Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcriptionQ24337398
Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.Q24537603
A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1Q24548862
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Negative and positive regulation of gene expression by mouse histone deacetylase 1Q24672508
An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3Q24682973
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Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in XenopusQ28307143
The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesisQ28504626
Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteriesQ28505293
Pod-1/Capsulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1Q28507235
Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organsQ28507663
Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic diseaseQ28508295
Pod1 is required in stromal cells for glomerulogenesisQ28509812
The basic helix-loop-helix transcription factor capsulin controls spleen organogenesisQ28510286
Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidneyQ28585814
Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling.Q42137346
Cell surface glycoconjugates and the extracellular matrix of the developing mouse embryo epicardiumQ42481029
PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.Q42491526
Epicardial development in lamprey supports an evolutionary origin of the vertebrate epicardium from an ancestral pronephric external glomerulusQ42525372
Analysis of the proepicardium-epicardium transition during the malformation of the RXRalpha-/- epicardiumQ42734016
Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.Q42757408
tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regenerationQ42766102
Vertebrate CASTOR is required for differentiation of cardiac precursor cells at the ventral midlineQ42868304
Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.Q42945812
Small heat shock protein Hsp27 is required for proper heart tube formationQ43146663
Regulation of neurocoel morphogenesis by Pard6 gamma b.Q43198871
alpha4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development.Q43512229
Distinct distribution of vimentin and cytokeratin in Xenopus oocytes and early embryosQ44590561
Use of Kikume green-red fusions to study the influence of pharmacological chaperones on trafficking of G protein-coupled receptorsQ45011170
Inhibition of α4-integrin stimulates epicardial–mesenchymal transformation and alters migration and cell fate of epicardially derived mesenchymeQ45258552
Communication between integrin receptors facilitates epicardial cell adhesion and matrix organization.Q45267926
Transforming growth factor-beta induces loss of epithelial character and smooth muscle cell differentiation in epicardial cellsQ46782583
Development of the proepicardial organ in the zebrafishQ46799857
Cloning and expression analysis of the mouse T-box gene Tbx18.Q47807069
Wilms' tumor suppressor gene is involved in the development of disparate kidney forms: evidence from expression in the Xenopus pronephrosQ48063713
SM22 alpha, a marker of adult smooth muscle, is expressed in multiple myogenic lineages during embryogenesisQ48066756
Distinct in vivo engraftment and growth patterns of t(1;19)+/E2A-PBX1+ and t(9;22)+/BCR-ABL+ human leukemia cells in SCID miceQ48276056
Development of the proepicardium in Xenopus laevisQ48743572
Morphological and molecular left-right asymmetries in the development of the proepicardium: a comparative analysis on mouse and chick embryosQ48744477
Evidence for an extracellular matrix bridge guiding proepicardial cell migration to the myocardium of chick embryos.Q50493507
Cellular characterization of MPZ mutations presenting with diverse clinical phenotypes.Q50553666
Preservation of left ventricular function and attenuation of remodeling after transplantation of human epicardium-derived cells into the infarcted mouse heart.Q50670579
Preparation of fixed Xenopus embryos for confocal imaging.Q51909183
Comparative gene expression analysis and fate mapping studies suggest an early segregation of cardiogenic lineages in Xenopus laevis.Q51928742
A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.Q52002879
A new direction for cardiac regeneration therapy: application of synergistically acting epicardium-derived cells and cardiomyocyte progenitor cellsQ39928426
PDGF-A as an epicardial mitogen during heart developmentQ40009186
Pod1 induces myofibroblast differentiation in mesenchymal progenitor cells from mouse kidneyQ40123333
Induction of proepicardial marker gene expression by the liver bud.Q40174197
The Wilms tumor suppressor Wt1 promotes cell adhesion through transcriptional activation of the alpha4integrin geneQ40241736
Glomerular permeability is altered by loss of P0, a myelin protein expressed in glomerular epithelial cellsQ40373511
Does the subepicardial mesenchyme contribute myocardioblasts to the myocardium of the chick embryo heart? A quail-chick chimera study tracing the fate of the epicardial primordiumQ40810484
Cytokeratins as a marker for epicardial formation in the quail embryoQ40984991
The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartmentsQ28586354
A Pbx1-dependent genetic and transcriptional network regulates spleen ontogenyQ28590235
REVIGO summarizes and visualizes long lists of gene ontology termsQ29614817
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTipsQ29614831
GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene listsQ29615019
Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus EmbryosQ29620084
Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early developmentQ30311953
Transient early embryonic expression of Nkx2-5 mutations linked to congenital heart defects in human causes heart defects in Xenopus laevisQ30480671
Use of KikGR a photoconvertible green-to-red fluorescent protein for cell labeling and lineage analysis in ES cells and mouse embryosQ30494573
BMP signals promote proepicardial protrusion necessary for recruitment of coronary vessel and epicardial progenitors to the heartQ30496194
Generation and characterization of iUBC-KikGR photoconvertible transgenic mice for live time-lapse imaging during developmentQ30523832
Cell type-dependent transactivation or repression of mesoderm-restricted basic helix-loop-helix protein, POD-1/CapsulinQ30872611
Analysis of TBX18 expression in chick embryosQ33204809
Discovering motifs in ranked lists of DNA sequencesQ33279806
GATA4/FOG2 transcriptional complex regulates Lhx9 gene expression in murine heart developmentQ33346498
SHP-2 is required for the maintenance of cardiac progenitorsQ33595597
Nuclear Import of Histone Deacetylase 5 by Requisite Nuclear Localization Signal PhosphorylationQ33748395
The BMP pathway acts to directly regulate Tbx20 in the developing heart.Q33840093
Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiationQ33929178
Tbx5 and Bmp signaling are essential for proepicardium specification in zebrafishQ33942656
Tazarotene-induced gene 1 inhibits prostaglandin E2-stimulated HCT116 colon cancer cell growthQ34086015
ClusterinQ34119745
Matrix remodeling in the ovary: regulation and functional role of the plasminogen activator and matrix metalloproteinase systemsQ34126544
Imbalance of Plasminogen Activator Inhibitor Type-1 (PAI-1) and Tissue Plasminogen Activator (t-PA) Activity in Patients With Noonan SyndromeQ34129775
Depletion of the actin bundling protein SM22/transgelin increases actin dynamics and enhances the tumourigenic phenotypes of cellsQ34132416
Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanomaQ34201939
Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cellsQ34261674
The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors.Q34273888
Ubiquitin-Proteasome-mediated degradation of Id1 is modulated by MyoD.Q34323067
Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation.Q34405424
A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1.Q34440327
Fluorescent proteins as proteomic probes.Q34450046
Xenbase: a Xenopus biology and genomics resourceQ34584638
S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activationQ34616744
Developmental expression of Pod 1 in Xenopus laevis.Q52056112
Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development.Q52116128
YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb.Q52176765
A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus.Q52247943
Pericardial mesoderm generates a population of coronary smooth muscle cells migrating into the heart along with ingrowth of the epicardial organ.Q53678848
Conditional inactivation of TGF-β type II receptor in smooth muscle cells and epicardium causes lethal aortic and cardiac defects.Q54688073
Myocardial infarction induces embryonic reprogramming of epicardial c-kit(+) cells: role of the pericardial fluid.Q54705281
Origin, fate, and function of epicardium-derived cells (EPDCs) in normal and abnormal cardiac development.Q55282875
Formation of the Venous Pole of the Heart From an Nkx2-5-Negative Precursor Population Requires Tbx18Q56000972
Identification of Myocardial and Vascular Precursor Cells in Human and Mouse EpicardiumQ61824978
Changes in C-terminal binding protein 2 (CtBP2) corepressor complex induced by E1A and modulation of E1A transcriptional activity by CtBP2Q64377469
Origin and development of the epicardium in the mouse embryoQ69193857
Early limb development of Xenopus laevisQ70705541
Left and right contributions to the Xenopus heart: implications for asymmetric morphogenesisQ73432592
Expression of smooth muscle alpha-actin in mesenchymal cells during formation of avian endocardial cushion tissue: A role for transforming growth factor β3Q73494345
Localization of the Wilm's tumour protein WT1 in avian embryosQ73724818
Smooth muscle cells and fibroblasts of the coronary arteries derive from epithelial-mesenchymal transformation of the epicardiumQ77296275
Expression of the bHLH transcription factor Tcf12 (ME1) gene is linked to the expansion of precursor cell populations during neurogenesisQ79773025
Rapid isolation of glomeruli coupled with gene expression profiling identifies downstream targets in Pod1 knockout miceQ81316661
In vivo and in vitro analysis of the vasculogenic potential of avian proepicardial and epicardial cellsQ82462288
Ca2+-binding protein S100A11: a novel diagnostic marker for breast carcinomaQ84013991
FGF-1 reverts epithelial-mesenchymal transition induced by TGF-{beta}1 through MAPK/ERK kinase pathwayQ84284635
The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epitheliaQ34718144
Roles of clusterin in progression, chemoresistance and metastasis of human ovarian cancerQ34977601
CtBP family proteins: more than transcriptional corepressorsQ35036904
Xenopus: An emerging model for studying congenital heart diseaseQ35075360
TBX5 is required for embryonic cardiac cell cycle progressionQ35129339
Transforming growth factor-beta stimulates epithelial-mesenchymal transformation in the proepicardiumQ35177514
The origins of cardiac tissue in the amphibian, Xenopus laevisQ35201190
TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancerQ35710117
SHP-2 acts via ROCK to regulate the cardiac actin cytoskeletonQ35741910
Efficient inducible Cre-mediated recombination in Tcf21 cell lineages in the heart and kidney.Q35756001
Xenopus as a model system for vertebrate heart developmentQ35793616
Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defectsQ35928623
Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart.Q36148533
Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signalingQ36151652
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.Q36163466
Instructive role of aPKCzeta subcellular localization in the assembly of adherens junctions in neural progenitorsQ36423540
Complementary proteomic analysis of protein complexes.Q36739823
Immunoisolation of protein complexes from XenopusQ36808221
Morpholino injection in XenopusQ36808239
Adult cardiac-resident MSC-like stem cells with a proepicardial originQ36838490
Pbx/Meis deficiencies demonstrate multigenetic origins of congenital heart diseaseQ37077784
Embryonic development of the proepicardium and coronary vesselsQ37098811
Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tractQ37188312
Lessons from the lily pad: Using Xenopus to understand heart diseaseQ37353967
A bHLH code for cardiac morphogenesisQ37662205
Xenopus explants as an experimental model system for studying heart development.Q37728660
Myocardial lineage developmentQ37819523
Signaling during epicardium and coronary vessel development.Q37967123
The arterial and cardiac epicardium in development, disease and repairQ38015007
Distinct enhancers regulate skeletal and cardiac muscle-specific expression programs of the cardiac alpha-actin gene in Xenopus embryosQ38289939
Expression of the smooth muscle cell calponin gene marks the early cardiac and smooth muscle cell lineages during mouse embryogenesisQ38360190
Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesisQ39096808
Developmental expression of the Xenopus laevis Tbx20 orthologueQ39096883
Distinct roles of HDAC1 and HDAC2 in transcription and recombination at the immunoglobulin loci in the chicken B cell line DT40.Q39698754
An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosisQ39792504
Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factor-signaling pathwaysQ39821385
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P1104number of pages13
P304page(s)2409-2421
P577publication date2013-05-01
P1433published inDevelopmentQ3025404
P1476titleTcf21 regulates the specification and maturation of proepicardial cells
P478volume140

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cites work (P2860)
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