review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Vladimir L. Gabai | Q54877934 |
P2093 | author name string | Julia Yaglom | |
Michael Y Sherman | |||
Cornelia O'Callaghan | |||
P2860 | cites work | Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line | Q70074091 |
Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs | Q73002431 | ||
Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts | Q73349019 | ||
A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents | Q78125095 | ||
High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways | Q79856384 | ||
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis | Q24681977 | ||
c-MYC: more than just a matter of life and death | Q28205057 | ||
Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein | Q28207814 | ||
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication | Q29617915 | ||
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75. | Q31048734 | ||
Mechanisms of apoptosis by c-Myc | Q33667315 | ||
Expression of heat shock proteins and heat shock protein messenger ribonucleic acid in human prostate carcinoma in vitro and in tumors in vivo. | Q33736465 | ||
Action of Myc in vivo - proliferation and apoptosis | Q33840451 | ||
Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent | Q33897870 | ||
Replicative senescence as a barrier to human cancer | Q33921353 | ||
Anoikis | Q33978500 | ||
Role of the heat shock response and molecular chaperones in oncogenesis and cell death | Q34052682 | ||
Four deaths and a funeral: from caspases to alternative mechanisms. | Q34325335 | ||
Heat shock proteins in cancer: chaperones of tumorigenesis | Q34495261 | ||
Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts | Q34552889 | ||
Invited review: Interplay between molecular chaperones and signaling pathways in survival of heat shock | Q34564831 | ||
Tumor cell senescence in cancer treatment | Q35143435 | ||
Senescence of human fibroblasts induced by oncogenic Raf. | Q35210205 | ||
Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases | Q35680797 | ||
The normal response to RAS: senescence or transformation? | Q35778503 | ||
"The stress of dying": the role of heat shock proteins in the regulation of apoptosis | Q35787941 | ||
A novel association between the human heat shock transcription factor 1 (HSF1) and prostate adenocarcinoma | Q35809875 | ||
Intrinsic tumour suppression | Q35953133 | ||
Ink4a/Arf links senescence and aging | Q35974880 | ||
The signals and pathways activating cellular senescence | Q36060167 | ||
Endothelial aging | Q36093530 | ||
Telomere and telomerase dynamics in human cells | Q36172564 | ||
Mesenchymal stem cell aging | Q36242270 | ||
p16INK4a as a second effector of the telomere damage pathway | Q36264069 | ||
Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways | Q36274956 | ||
Senescence of hematopoietic stem cells and bone marrow failure | Q36278284 | ||
Proliferative senescence in hematopoietic stem cells during ex-vivo expansion | Q36355574 | ||
Premature senescence of endothelial cells: Methusaleh's dilemma | Q36444277 | ||
Stop and go: anti-proliferative and mitogenic functions of the transcription factor C/EBPbeta | Q36474712 | ||
Telomeres: cancer to human aging | Q36528826 | ||
p53-Dependent and -independent functions of the Arf tumor suppressor | Q36547718 | ||
DeltaNp63alpha up-regulates the Hsp70 gene in human cancer | Q38330737 | ||
Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites | Q38350716 | ||
Apoptosis mediated by p53 in rat neural AF5 cells following treatment with hydrogen peroxide and staurosporine | Q40245002 | ||
Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides. | Q40370477 | ||
Differential oncogenic Ras signaling and senescence in tumor cells | Q40502532 | ||
Activation of ATM and phosphorylation of p53 by heat shock | Q40750164 | ||
The role of bcl-2 expression in breast carcinomas (Review). | Q40849081 | ||
Genetic differences between the pancytosolic and perinuclear forms of murine mortalin. | Q41179798 | ||
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms | Q41197754 | ||
NIH 3T3 cells malignantly transformed by mot-2 show inactivation and cytoplasmic sequestration of the p53 protein | Q42806765 | ||
Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member. | Q42825164 | ||
Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function. | Q42832610 | ||
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis | Q44681202 | ||
Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion | Q46230264 | ||
Molecular chaperones and the stress of oncogenesis | Q47785215 | ||
Demonstration of selective protein complexes of p53 with 73 kDa heat shock cognate protein, but not with 72 kDa heat shock protein in human tumor cells. | Q53478145 | ||
Molecular signature of oncogenic ras-induced senescence. | Q53632631 | ||
Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. | Q53851410 | ||
Escape from premature senescence is not sufficient for oncogenic transformation by Ras. | Q54021692 | ||
Executing Cell Senescence | Q57580197 | ||
Executing cell senescence | Q57580253 | ||
Hsp70-2 is required for tumor cell growth and survival | Q59487815 | ||
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | molecular chaperones | Q422496 |
P304 | page(s) | 3711-3715 | |
P577 | publication date | 2007-05-25 | |
P1433 | published in | FEBS Letters | Q1388051 |
P1476 | title | Molecular chaperones regulate p53 and suppress senescence programs | |
P478 | volume | 581 |
Q42552152 | Analogs of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, as Anti-Cancer Agents |
Q39227263 | Biological features of core networks that result from a high-fat diet in hepatic and pulmonary tissues in mammary tumour-bearing, obesity-resistant mice |
Q43061452 | Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability |
Q33972062 | Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining |
Q42494627 | E6AP is required for replicative and oncogene-induced senescence in mouse embryo fibroblasts |
Q33956906 | Heat shock protein 70 (hsp70) as an emerging drug target. |
Q37033622 | Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. |
Q35070272 | Heat shock proteins in breast cancer progression--a suitable case for treatment? |
Q37329764 | Hsps and aging |
Q49012326 | Ischaemia-induced protein ubiquitinylation is differentially accompanied with heat-shock protein 70 expression after naïve and preconditioned ischaemia |
Q33700800 | Prognostic implication of HSPA (HSP70) in breast cancer patients treated with neoadjuvant anthracycline-based chemotherapy. |
Q34632255 | The complexities of p97 function in health and disease |
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