scholarly article | Q13442814 |
P2093 | author name string | Vernadeth B Alarcon | |
Yusuke Marikawa | |||
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Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity | Q24305492 | ||
Human isoprenoid synthase enzymes as therapeutic targets | Q26822639 | ||
Squalene synthase as a target for Chagas disease therapeutics | Q27683611 | ||
Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human | Q28140183 | ||
Pharmacologic inhibition of squalene synthase and other downstream enzymes of the cholesterol synthesis pathway: a new therapeutic approach to treatment of hypercholesterolemia | Q28241294 | ||
Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis | Q28259767 | ||
Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development | Q28506302 | ||
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass | Q28508262 | ||
Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene | Q28585227 | ||
Protein prenylation: molecular mechanisms and functional consequences | Q29618038 | ||
Cell polarity regulator PARD6B is essential for trophectoderm formation in the preimplantation mouse embryo | Q30496176 | ||
Rho-associated kinase activity is required for proper morphogenesis of the inner cell mass in the mouse blastocyst | Q30650902 | ||
Towards complete sets of farnesylated and geranylgeranylated proteins | Q33281289 | ||
Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst | Q34098464 | ||
Making the blastocyst: lessons from the mouse | Q34108232 | ||
Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors | Q34207135 | ||
The Hippo pathway member Nf2 is required for inner cell mass specification | Q34352625 | ||
Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos. | Q34352631 | ||
Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice | Q34519891 | ||
Hippo signaling: growth control and beyond | Q34625638 | ||
Teratogenic risk of statins in pregnancy | Q34643449 | ||
GGTI-298 induces G0-G1 block and apoptosis whereas FTI-277 causes G2-M enrichment in A549 cells | Q73352842 | ||
HMG-CoA reductase activity in human liver microsomes: comparative inhibition by statins | Q74244593 | ||
Advanced maternal age--how old is too old? | Q80961581 | ||
Mechanistic and epidemiologic considerations in the evaluation of adverse birth outcomes following gestational exposure to statins | Q81012782 | ||
A second gene for peroxisomal HMG-CoA reductase? A genomic reassessment | Q35009941 | ||
Targeting cellular squalene synthase, an enzyme essential for cholesterol biosynthesis, is a potential antiviral strategy against hepatitis C virus | Q35115534 | ||
Statins and congenital malformations: cohort study | Q35184473 | ||
Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst | Q35500567 | ||
Transcription factor AP-2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage | Q35568256 | ||
Cell signaling and transcription factors regulating cell fate during formation of the mouse blastocyst | Q35812175 | ||
Human hypoblast formation is not dependent on FGF signalling. | Q36011255 | ||
Thematic review series: lipid posttranslational modifications. CAAX modification and membrane targeting of Ras. | Q36423684 | ||
Creation of trophectoderm, the first epithelium, in mouse preimplantation development | Q36812023 | ||
Targeting GGTase-I activates RHOA, increases macrophage reverse cholesterol transport, and reduces atherosclerosis in mice | Q37613222 | ||
Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease | Q37734257 | ||
Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain. | Q38003481 | ||
The pharmacology of statins | Q38198397 | ||
Developmental processes regulated by the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway: highlights from animal studies. | Q38204597 | ||
Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2. | Q38469639 | ||
Simvastatin decreases steroid production in the H295R cell line and decreases steroids and FSH in female rats | Q38827126 | ||
Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse | Q39221968 | ||
Cerivastatin: pharmacology of a novel synthetic and highly active HMG-CoA reductase inhibitor | Q41077310 | ||
Isopentenoid synthesis in isolated embryonic Drosophila cells. Farnesol catabolism and omega-oxidation | Q42213004 | ||
Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms | Q42551803 | ||
Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells | Q42774013 | ||
RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription. | Q42799714 | ||
YM-53601, a novel squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in several animal species | Q43264545 | ||
Selective inhibition of cancer cell invasion by a geranylgeranyltransferase-I inhibitor | Q44642906 | ||
Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins. | Q44672657 | ||
Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage | Q46697212 | ||
Twenty-year trends in serum cholesterol, hypercholesterolemia, and cholesterol medication use: the Minnesota Heart Survey, 1980-1982 to 2000-2002. | Q46847931 | ||
Par-aPKC-dependent and -independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16-cell stage mouse embryos. | Q48122097 | ||
Cdc42 is implicated in polarity during meiotic resumption and blastocyst formation in the mouse. | Q50641857 | ||
POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos. | Q50645942 | ||
Embryonic lethality and defective neural tube closure in mice lacking squalene synthase. | Q52173967 | ||
Mevalonate reverses the developmental arrest of preimplantation mouse embryos by Compactin, an inhibitor of HMG Co A reductase. | Q52280983 | ||
Metabolic control of YAP and TAZ by the mevalonate pathway. | Q52768568 | ||
Na(+)-independent multispecific anion transporter mediates active transport of pravastatin into rat liver. | Q54053959 | ||
Shifts in intended and unintended pregnancies in the United States, 2001-2008. | Q54417497 | ||
Isoprenylation of brain 2',3'-cyclic nucleotide 3'-phosphodiesterase modulates cell morphology. | Q55481611 | ||
Effect of the new HMG-CoA reductase inhibitor cerivastatin (BAY W 6228)on migration, proliferation and cholesterol synthesis in arterial myocytes | Q71559207 | ||
Fertility and general reproduction studies in rats with the HMG-CoA reductase inhibitor, atorvastatin | Q71784154 | ||
Different effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on sterol synthesis in various human cell types | Q72385555 | ||
Clinical pharmacokinetics of pravastatin | Q72793356 | ||
Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol | Q73182577 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 5 | |
P304 | page(s) | 350-363 | |
P577 | publication date | 2016-02-07 | |
P1433 | published in | Molecular Human Reproduction | Q15761794 |
P1476 | title | Statins inhibit blastocyst formation by preventing geranylgeranylation | |
P478 | volume | 22 |
Q36245452 | GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. |
Q58611356 | RHOA activity in expanding blastocysts is essential to regulate HIPPO-YAP signaling and to maintain the trophectoderm-specific gene expression program in a ROCK/actin filament-independent manner |
Q47816345 | ROCK and RHO Playlist for Preimplantation Development: Streaming to HIPPO Pathway and Apicobasal Polarity in the First Cell Differentiation |
Q47100063 | Regulation of Tissue Growth by the Mammalian Hippo Signaling Pathway. |
Q92213622 | Two new mixed-ligand coordination polymers based on multi-N chelating ligand inhibit YAP expression and induce caspase-mediated spinal tumor cell apoptosis |
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