scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1040977830 |
P356 | DOI | 10.1038/SREP25108 |
P932 | PMC publication ID | 4848494 |
P698 | PubMed publication ID | 27121375 |
P50 | author | Jordan A Beard | Q59691696 |
Justin Hills | Q57902125 | ||
P2093 | author name string | Taosheng Chen | |
Yong-Dong Wang | |||
Milu T Cherian | |||
Alexa Tenga | |||
Jessica D Hoyer | |||
P2860 | cites work | Human MicroRNA targets | Q21563637 |
p53 mediates the negative regulation of MDM2 by orphan receptor TR3 | Q24321873 | ||
Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation | Q24530187 | ||
The NR4A subgroup: immediate early response genes with pleiotropic physiological roles | Q24540372 | ||
PUMA mediates the apoptotic response to p53 in colorectal cancer cells | Q24550772 | ||
MicroRNAs: target recognition and regulatory functions | Q24609584 | ||
miR-34a repression of SIRT1 regulates apoptosis | Q24652720 | ||
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53 | Q24657532 | ||
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 | Q27642888 | ||
DNA hypermethylation of microRNA-34b/c has prognostic value for stage Ⅰ non-small cell lung cancer | Q83557235 | ||
MicroRNA-34a modulates chemosensitivity of breast cancer cells to adriamycin by targeting Notch1 | Q85240544 | ||
Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells. | Q39584006 | ||
Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer | Q39592978 | ||
Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells | Q39633529 | ||
Cytoplasmic mislocalization of the orphan nuclear receptor Nurr1 is a prognostic factor in bladder cancer | Q39775794 | ||
NGFI-B nuclear orphan receptor Nurr1 interacts with p53 and suppresses its transcriptional activity. | Q39813907 | ||
A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene | Q39978280 | ||
Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer | Q40350277 | ||
Intact p53-dependent responses in miR-34-deficient mice. | Q42251432 | ||
Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis | Q46727309 | ||
Reduced levels of miR-34a in neuroblastoma are not caused by mutations in the TP53 binding site. | Q47992879 | ||
Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy. | Q50870764 | ||
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. | Q53306726 | ||
Combinatorial microRNA target predictions | Q27860510 | ||
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets | Q27860792 | ||
The miR-34 family in cancer and apoptosis | Q28245865 | ||
p21 is necessary for the p53-mediated G1 arrest in human cancer cells | Q28291118 | ||
Principles for modulation of the nuclear receptor superfamily | Q28291197 | ||
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer | Q28291502 | ||
A microRNA component of the p53 tumour suppressor network | Q28305330 | ||
In-depth analysis shows synergy between erlotinib and miR-34a | Q28539851 | ||
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis | Q29547575 | ||
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis | Q29619556 | ||
Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells | Q33386807 | ||
Frequent downregulation of miR-34 family in human ovarian cancers | Q33658229 | ||
A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation | Q33825730 | ||
Identification of microRNA-regulated gene networks by expression analysis of target genes | Q34255426 | ||
Dichotomous roles for the orphan nuclear receptor NURR1 in breast cancer | Q34630752 | ||
miR-34 - a microRNA replacement therapy is headed to the clinic | Q34640230 | ||
The interplay of NR4A receptors and the oncogene-tumor suppressor networks in cancer | Q34771536 | ||
Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements | Q34865226 | ||
Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair | Q35393272 | ||
MiR-34b is associated with clinical outcome in triple-negative breast cancer patients | Q35950656 | ||
MicroRNA-132 promotes estradiol synthesis in ovarian granulosa cells via translational repression of Nurr1. | Q35964665 | ||
The predictive effect of overexpressed miR-34a on good survival of cancer patients: a systematic review and meta-analysis | Q36111707 | ||
NuMA is required for the selective induction of p53 target genes | Q36978256 | ||
1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth | Q37104035 | ||
Nuclear receptor drug discovery | Q37229006 | ||
miR-137 regulates the constitutive androstane receptor and modulates doxorubicin sensitivity in parental and doxorubicin-resistant neuroblastoma cells | Q37581142 | ||
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression. | Q37631219 | ||
Targeting of mRNAs by multiple miRNAs: the next step | Q37700158 | ||
Therapeutic targeting of microRNAs: current status and future challenges | Q38228101 | ||
Mir-34: a new weapon against cancer? | Q38253374 | ||
Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy. | Q39131387 | ||
miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression | Q39397509 | ||
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy | Q39465507 | ||
PGE₂ targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction | Q39542863 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | microRNA | Q310899 |
P304 | page(s) | 25108 | |
P577 | publication date | 2016-04-28 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | The orphan nuclear receptor NR4A2 is part of a p53-microRNA-34 network | |
P478 | volume | 6 |
Q41774349 | Activated Notch signaling augments cell growth in hepatocellular carcinoma via up-regulating the nuclear receptor NR4A2. |
Q89859882 | Increased miR-34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS-JNK-p53 pathway in Alzheimer's Disease |
Q92189114 | Joint Transcriptomic Analysis of Lung Cancer and Other Lung Diseases |
Q46150904 | Long 3'UTR of Nurr1 mRNAs is targeted by miRNAs in mesencephalic dopamine neurons |
Q47329715 | MicroRNA-137 promotes endothelial progenitor cell proliferation and angiogenesis in cerebral ischemic stroke mice by targeting NR4A2 through the Notch pathway. |
Q61800287 | MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer |
Q93222983 | Orphan receptor NR4A3 is a novel target of p53 that contributes to apoptosis |
Q39015118 | Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis |
Q64259767 | Roles of MicroRNA-34a in Epithelial to Mesenchymal Transition, Competing Endogenous RNA Sponging and Its Therapeutic Potential |
Q47148529 | miR-145-5p/Nurr1/TNF-α Signaling-Induced Microglia Activation Regulates Neuron Injury of Acute Cerebral Ischemic/Reperfusion in Rats |
Q47660322 | miR-34a Regulates Expression of the Stathmin-1 Oncoprotein and Prostate Cancer Progression |
Search more.