Impact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells

scientific article published on 30 April 2013

Impact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2013/589474
P932PMC publication ID3657404
P698PubMed publication ID23738337
P5875ResearchGate publication ID237058311

P2093author name stringLi Liu
Yong Xu
Xia Li
Jianhua Zhu
Jianhua He
Guo Chen
Lan Jiang
Chenlin Gao
P2860cites workMechanisms of TGF-beta signaling from cell membrane to the nucleusQ27860785
Chromatin modifications and their functionQ27861067
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injuryQ28569252
Histone deacetylase inhibition attenuates diabetes-associated kidney growth: potential role for epigenetic modification of the epidermal growth factor receptorQ28570826
Early intensive insulin therapy attenuates the p38 pathway in the renal cortex and indices of nephropathy in diabetic rats.Q50983953
Optimizing Allocation of Kidneys from Older DonorsQ57702068
Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetesQ80441677
Effects of proteasome inhibitors on rat renal fibrosis in vitro and in vivoQ82984012
MG132 treatment attenuates cardiac remodeling and dysfunction following aortic banding in rats via the NF-κB/TGFβ1 pathwayQ83655968
Epigenetic Histone Methylation Modulates Fibrotic Gene ExpressionQ28579049
Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC)Q28579534
CPVL/CHN2 genetic variant is associated with diabetic retinopathy in Chinese type 2 diabetic patientsQ34215763
Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1.Q34237731
Epigenetics: deciphering its role in diabetes and its chronic complicationsQ35068854
Epigenetics in diabetic kidney diseaseQ35647853
Metabolic memory and chronic diabetes complications: potential role for epigenetic mechanismsQ36205231
Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cellsQ36699878
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemiaQ36916418
Structure and mechanism of lysine-specific demethylase enzymesQ36952934
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tailQ37163462
Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trialsQ37464743
Epigenetic mechanisms that underpin metabolic and cardiovascular diseasesQ37504694
Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanismsQ37737556
RAGE and the pathogenesis of chronic kidney diseaseQ37737557
New pharmacological treatments for improving renal outcomes in diabetesQ37741787
Glycemic memory associated epigenetic changesQ37769811
Core histone H2A ubiquitylation and transcriptional regulationQ37777788
Diabetic nephropathy -- a multifaceted target of new therapies.Q37814528
Diabetes-induced epigenetic signature in vascular cellsQ37974943
Chromatin modifications associated with diabetesQ38013734
Proteasome inhibitor MG132 induces selective apoptosis in glioblastoma cells through inhibition of PI3K/Akt and NFkappaB pathways, mitochondrial dysfunction, and activation of p38-JNK1/2 signaling.Q39389835
Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β.Q39400684
Apoptosis inducer NGFI-B is degraded by the proteasome and stabilized by treatment with EGF.Q39414278
Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cellsQ39444957
Tubular injury in a rat model of type 2 diabetes is prevented by metformin: a possible role of HIF-1α expression and oxygen metabolismQ39599967
Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylasesQ41128716
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblastsQ46892901
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectmesangial cellQ3331086
protein ubiquitinationQ3547638
P304page(s)589474
P577publication date2013-04-30
P1433published inJournal of Diabetes ResearchQ26841822
P1476titleImpact of high glucose and proteasome inhibitor MG132 on histone H2A and H2B ubiquitination in rat glomerular mesangial cells
P478volume2013

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cites work (P2860)
Q57287866Apelin inhibited epithelial-mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i
Q36214096Genome-wide DNA methylation analysis identifies a metabolic memory profile in patient-derived diabetic foot ulcer fibroblasts
Q35196185High glucose induces sumoylation of Smad4 via SUMO2/3 in mesangial cells
Q37553460MG132 ameliorates kidney lesions by inhibiting the degradation of Smad7 in streptozotocin-induced diabetic nephropathy
Q29248428Maresin 1 Mitigates High Glucose-Induced Mouse Glomerular Mesangial Cell Injury by Inhibiting Inflammation and Fibrosis
Q47711556Non-genetic mechanisms of diabetic nephropathy
Q33676124Posttranslational modification of mitochondrial transcription factor A in impaired mitochondria biogenesis: implications in diabetic retinopathy and metabolic memory phenomenon.
Q37590421The genetics of diabetic nephropathy.
Q33786922The role of ubiquitination and sumoylation in diabetic nephropathy.

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