review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1051279968 |
P356 | DOI | 10.1038/NRC3006 |
P932 | PMC publication ID | 3659810 |
P698 | PubMed publication ID | 21346784 |
P5875 | ResearchGate publication ID | 49967469 |
P2093 | author name string | Paul W Doetsch | |
Damien Brégeon | |||
P2860 | cites work | Blockage of RNA polymerase as a possible trigger for u.v. light-induced apoptosis | Q71408610 |
Incorrect base insertion and prematurely terminated transcripts during T7 RNA polymerase transcription elongation past benzo[a]pyrenediol epoxide-modified DNA | Q71850770 | ||
U.v.-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle | Q72185052 | ||
Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene) | Q72850833 | ||
Transcription bypass or blockage at single-strand breaks on the DNA template strand: effect of different 3' and 5' flanking groups on the T7 RNA polymerase elongation complex | Q72891362 | ||
In vivo technique for determining transcriptional mutagenesis | Q73044780 | ||
The oxidative DNA lesion 8,5'-(S)-cyclo-2'-deoxyadenosine is repaired by the nucleotide excision repair pathway and blocks gene expression in mammalian cells | Q73763148 | ||
Highly mutagenic bypass synthesis by T7 RNA polymerase of site-specific benzo[a]pyrene diol epoxide-adducted template DNA | Q74531765 | ||
Phenotypic change caused by transcriptional bypass of uracil in nondividing cells | Q74672155 | ||
Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome | Q81576390 | ||
Retraction | Q81861539 | ||
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines | Q24535948 | ||
RNA-Seq: a revolutionary tool for transcriptomics | Q24596169 | ||
Mechanism of transcriptional stalling at cisplatin-damaged DNA | Q27648994 | ||
Molecular Basis of Transcriptional Mutagenesis at 8-Oxoguanine | Q27657438 | ||
Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients | Q28258349 | ||
Endogenous DNA damage in humans: a review of quantitative data | Q28259993 | ||
Genomic instability--an evolving hallmark of cancer | Q28274009 | ||
Mutagenesis by apurinic/apyrimidinic sites | Q28300337 | ||
The current evidence for defective repair of oxidatively damaged DNA in Cockayne syndrome | Q28307972 | ||
Effect of thymine glycol on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II | Q28360336 | ||
Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells | Q28475782 | ||
Transcription-coupled DNA repair: two decades of progress and surprises | Q29614662 | ||
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG | Q29616532 | ||
HSP90 at the hub of protein homeostasis: emerging mechanistic insights | Q29616824 | ||
DNA replication fidelity | Q29616841 | ||
NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dG) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).dA(anti) alignment at lesion site | Q68189284 | ||
An RNA polymerase mutant with reduced accuracy of chain elongation | Q70315148 | ||
Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells | Q30856746 | ||
RPA and ATR link transcriptional stress to p53 | Q33290206 | ||
Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli. | Q33734755 | ||
Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase | Q33819287 | ||
Role of oxidatively induced DNA lesions in human pathogenesis | Q34091785 | ||
Error-prone repair DNA polymerases in prokaryotes and eukaryotes | Q34131455 | ||
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase | Q34342518 | ||
Repair and genetic consequences of endogenous DNA base damage in mammalian cells | Q34371854 | ||
Escherichia coli RNA and DNA polymerase bypass of dihydrouracil: mutagenic potential via transcription and replication | Q34660557 | ||
DNA polymerases and human disease | Q34795963 | ||
Translesion synthesis by RNA polymerases: occurrence and biological implications for transcriptional mutagenesis | Q35013058 | ||
Cell-selfish modes of evolution and mutations directed after transcriptional bypass | Q35013064 | ||
DNA repair in terminally differentiated cells | Q35037473 | ||
RNA repair: damage control | Q35157587 | ||
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors | Q35191105 | ||
Oxidized messenger RNA induces translation errors | Q35576065 | ||
Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development? | Q35592874 | ||
Transcriptional bypass of bulky DNA lesions causes new mutant RNA transcripts in human cells | Q35752678 | ||
Genetic effects of oxidative DNA damage: comparative mutagenesis of 7,8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine in Escherichia coli | Q35935140 | ||
Oxidized, deaminated cytosines are a source of C --> T transitions in vivo | Q36005669 | ||
Nature and nurture - lessons from chemical carcinogenesis | Q36014330 | ||
Use of an in vivo reporter assay to test for transcriptional and translational fidelity in yeast | Q36021423 | ||
T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation | Q36034196 | ||
Thymine glycol lesions terminate chain elongation by DNA polymerase I in vitro | Q36089095 | ||
Oxidative stress and reactive oxygen species | Q36117924 | ||
Hypothetical role of RNA damage avoidance in preventing human disease. | Q36139539 | ||
Evidence from in vitro replication that O6-methylguanine can adopt multiple conformations | Q36274826 | ||
Is base excision repair a tumor suppressor mechanism? | Q36371079 | ||
RNA polymerase encounters with DNA damage: transcription-coupled repair or transcriptional mutagenesis? | Q36389652 | ||
Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases | Q36421100 | ||
RNA polymerase bypass at sites of dihydrouracil: implications for transcriptional mutagenesis | Q36556230 | ||
The mechanics of base excision repair, and its relationship to aging and disease | Q36656724 | ||
Base excision repair, aging and health span. | Q36853499 | ||
Base excision repair modulation as a risk factor for human cancers | Q36880317 | ||
Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase | Q36948658 | ||
Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase | Q36972108 | ||
8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells | Q36999922 | ||
Base excision repair of oxidative DNA damage and association with cancer and aging | Q37090426 | ||
Splice-site pairing is an intrinsically high fidelity process. | Q37100836 | ||
Potential role of phenotypic mutations in the evolution of protein expression and stability | Q37159074 | ||
DNA repair in mammalian cells: Transcription-coupled DNA repair: directing your effort where it's most needed | Q37372523 | ||
The evolutionary consequences of erroneous protein synthesis. | Q37393307 | ||
Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells | Q37416480 | ||
Replication of acetylaminofluorene-adducted plasmids in human cells: spectrum of base substitutions and evidence of excision repair | Q37621481 | ||
Translational control in cancer. | Q37717999 | ||
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine | Q37732850 | ||
Transcription through 8-oxoguanine in DNA repair-proficient and Csb(-)/Ogg1(-) DNA repair-deficient mouse embryonic fibroblasts is dependent upon promoter strength and sequence context | Q40107274 | ||
The control of accuracy during protein synthesis in Escherichia coli and perturbations of this control by streptomycin, neomycin, or ribosomal mutations | Q40110360 | ||
In vitro replication by prokaryotic and eukaryotic polymerases on DNA templates containing site-specific and stereospecific benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide adducts | Q40393765 | ||
Mutation in resting cells: the role of endogenous DNA damage. | Q41284321 | ||
Starvation-associated mutation in Escherichia coli: a spontaneous lesion hypothesis for "directed" mutation | Q41661611 | ||
Transient reversal of RNA polymerase II active site closing controls fidelity of transcription elongation | Q42658374 | ||
Global effects of mistranslation from an editing defect in mammalian cells | Q42834340 | ||
Editorial expression of concern | Q42960154 | ||
DNA polymerases beta and lambda bypass thymine glycol in gapped DNA structures | Q43084236 | ||
Site-directed mutagenesis for quantitation of base-base interactions at defined sites | Q43567455 | ||
Peroxynitrite-induced reactions of synthetic oligo 2'-deoxynucleotides and DNA containing guanine: formation and stability of a 5-guanidino-4-nitroimidazole lesion | Q44014132 | ||
Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis. | Q44238573 | ||
Effects of DNA lesions on transcription elongation by T7 RNA polymerase | Q44342277 | ||
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions | Q44480509 | ||
Transcriptional mutagenesis induced by uracil and 8-oxoguanine in Escherichia coli. | Q44633186 | ||
Mapping adducts of DNA structural probes using transcription and primer extension approaches | Q44829852 | ||
Transcription activities at 8-oxoG lesions in DNA. | Q45067806 | ||
Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli | Q45199588 | ||
Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts | Q46675864 | ||
Cancerous hyper-mutagenesis in p53 genes is possibly associated with transcriptional bypass of DNA lesions | Q47566790 | ||
Effects of nonbulky DNA base damages on Escherichia coli RNA polymerase-mediated elongation and promoter clearance | Q47724007 | ||
Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF. | Q48292696 | ||
Reliable method for generating double-stranded DNA vectors containing site-specific base modifications. | Q51577382 | ||
Mutagenesis by single site-specific arylamine-DNA adducts. Induction of mutations at multiple sites. | Q53512360 | ||
Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues. | Q53990151 | ||
Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta. | Q54055057 | ||
DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. | Q54446139 | ||
Assays for transcriptional mutagenesis in active genes. | Q54462706 | ||
Counteraction by MutT protein of transcriptional errors caused by oxidative damage. | Q54558346 | ||
Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule". | Q54565641 | ||
Template strand gap bypass is a general property of prokaryotic RNA polymerases: implications for elongation mechanisms. | Q54576634 | ||
Efficient Bypass and Base Misinsertions at Abasic Sites by Prokaryotic RNA Polymerasesa | Q54630140 | ||
Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. | Q54710915 | ||
Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments | Q64866811 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 218-227 | |
P577 | publication date | 2011-03-01 | |
P1433 | published in | Nature Reviews Cancer | Q641657 |
P1476 | title | Transcriptional mutagenesis: causes and involvement in tumour development | |
P478 | volume | 11 |
Q55416915 | A Genome-Wide Assay Specifies Only GreA as a Transcription Fidelity Factor in Escherichia coli. |
Q33558016 | A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine |
Q36431367 | A quantitative assay for assessing the effects of DNA lesions on transcription |
Q40086673 | Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations. |
Q36724941 | BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G1 phase of the cell cycle |
Q45961755 | Chemical Analysis of DNA Damage. |
Q28709604 | DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae |
Q34727858 | DNA repair mechanisms in dividing and non-dividing cells |
Q42149827 | Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity |
Q36436001 | Effects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells |
Q54478463 | Effects of DNA lesions on the transcription reaction of mitochondrial RNA polymerase: implications for bypass RNA synthesis on oxidative DNA lesions. |
Q34507760 | Effects of Tet-mediated oxidation products of 5-methylcytosine on DNA transcription in vitro and in mammalian cells |
Q36064927 | Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells |
Q35754741 | Evidence for Retromutagenesis as a Mechanism for Adaptive Mutation in Escherichia coli |
Q95300387 | Hypermutation in single-stranded DNA |
Q89311743 | Immune Surveillance by Natural IgM Is Required for Early Neoantigen Recognition and Initiation of Adaptive Immunity |
Q47363972 | In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities. |
Q26824755 | Is neurodegenerative disease a long-latency response to early-life genotoxin exposure? |
Q37304675 | Mass Spectrometry-Based Quantitative Strategies for Assessing the Biological Consequences and Repair of DNA Adducts |
Q46444604 | Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis |
Q35062546 | Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions |
Q39384000 | Mechanistic insights into transcription coupled DNA repair |
Q38207228 | Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis |
Q33606811 | Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis |
Q90601695 | Next-Generation Genotoxicology: Using Modern Sequencing Technologies to Assess Somatic Mutagenesis and Cancer Risk |
Q34069546 | Nucleotide excision repair in Trypanosoma brucei: specialization of transcription-coupled repair due to multigenic transcription |
Q52718714 | O6-methylguanine-induced transcriptional mutagenesis reduces p53 tumor-suppressor function. |
Q37194752 | Oxidative damage and mutagenesis in Saccharomyces cerevisiae: genetic studies of pathways affecting replication fidelity of 8-oxoguanine |
Q41628843 | Position-dependent effects of regioisomeric methylated adenine and guanine ribonucleosides on translation |
Q36440706 | Quantitative measurement of transcriptional inhibition and mutagenesis induced by site-specifically incorporated DNA lesions in vitro and in vivo |
Q37174539 | RNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modifications |
Q38590733 | RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications |
Q38117538 | RNA polymerase between lesion bypass and DNA repair |
Q37287385 | Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions |
Q42365650 | Six Germline Genetic Variations Impair the Translesion Synthesis Activity of Human DNA Polymerase κ. |
Q87900920 | Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II |
Q90318020 | The DNA damage response to transcription stress |
Q38780730 | The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro |
Q34711951 | Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II. |
Q35098098 | Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA. |
Q27015664 | Transcriptional mutagenesis and its potential roles in the etiology of cancer and bacterial antibiotic resistance |
Q26796502 | Transcriptional mutagenesis by 8-oxodG in α-synuclein aggregation and the pathogenesis of Parkinson's disease |
Q98386063 | Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape |
Q40951385 | Transcriptional mutagenesis reduces splicing fidelity in mammalian cells. |
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