Matrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression

scientific article published on 4 May 2016

Matrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1016816655
P356DOI10.1038/SREP25401
P8608Fatcat IDrelease_rfta4ciur5cepakldckfbobiii
P932PMC publication ID4855171
P698PubMed publication ID27142968

P2093author name stringYue Zhou
Huan Liu
Chao Sun
Yuan Yao
Bo Huang
Xin Fan
Xiu-Wu Bian
You-Hong Cui
Ming-Han Liu
P2860cites workRole of the mouse ank gene in control of tissue calcification and arthritisQ22254612
Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasiaQ24291173
Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANKQ24533484
Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKHQ24561827
Matrix elasticity directs stem cell lineage specificationQ27860761
microRNAs: tiny regulators with great potentialQ28214699
Cell locomotion and focal adhesions are regulated by substrate flexibilityQ29615522
Innervation, inflammation, and hypermobility may characterize pathologic disc degeneration: review of animal model dataQ31036108
Role of the progressive ankylosis gene (ank) in cartilage mineralizationQ33551454
Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemiaQ33727722
Epidemiology, etiology, diagnostic evaluation, and treatment of low back painQ73554628
Calcification in human intervertebral disc degeneration and scoliosisQ84136439
Structural and functional changes of the articular surface in a post-traumatic model of early osteoarthritis measured by atomic force microscopyQ84980365
The measurement of biomechanical properties of porcine articular cartilage using atomic force microscopyQ33864556
Atomic force microscopy: a nanoscopic window on the cell surfaceQ33929811
Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactionsQ34075531
Degenerative disk disease: assessment of changes in vertebral body marrow with MR imagingQ34174849
Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopyQ34185769
ECM stiffness primes the TGFβ pathway to promote chondrocyte differentiationQ34290357
Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopyQ34957893
Biochemical and genetic analysis of ANK in arthritis and bone diseaseQ35221731
Nutrition of the intervertebral discQ35963858
The vertebral endplate: disc degeneration, disc regenerationQ36525852
Pharmacological enhancement of disc diffusion and differentiation of healthy, ageing and degenerated discs : Results from in-vivo serial post-contrast MRI studies in 365 human lumbar discsQ36632647
Dicer-dependent pathways regulate chondrocyte proliferation and differentiationQ36882995
Cellular sources of extracellular matrix in hepatic fibrosisQ37045419
Low-back pain, its origin and risk indicatorsQ37088948
Stimulation of adipogenesis of adult adipose-derived stem cells using substrates that mimic the stiffness of adipose tissue.Q37206807
Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritisQ37253924
The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells.Q37306467
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression.Q37694973
Articular cartilage and subchondral bone in the pathogenesis of osteoarthritisQ37730927
Pathophysiology of articular chondrocalcinosis--role of ANKH.Q37811887
MicroRNAs regulate osteogenesis and chondrogenesisQ37981529
MicroRNA in intervertebral disc degeneration.Q38367405
Transport properties of the human cartilage endplate in relation to its composition and calcificationQ39423136
MicroRNA regulation associated chondrogenesis of mouse MSCs grown on polyhydroxyalkanoatesQ39526269
A novel in vitro culture system for analysis of functional role of phosphate transport in endochondral ossification.Q40871962
MicroRNA-765 influences arterial stiffness through modulating apelin expressionQ41060142
Matrix stiffness determines the fate of nucleus pulposus-derived stem cells.Q41335817
Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffeningQ41929558
Electrospun cross-linked gelatin fibers with controlled diameter: the effect of matrix stiffness on proliferative and biosynthetic activity of chondrocytes cultured in vitro.Q42914111
Intermittent Cyclic Mechanical Tension-Induced Calcification and downregulation of ankh gene expression of end plate chondrocytesQ43972596
Epidemiology and impact of low-back painQ44588243
Parallel regulation of extracellular ATP and inorganic pyrophosphate: roles of growth factors, transduction modulators, and ANK.Q46296193
YAP-mediated regulation of the chondrogenic phenotype in response to matrix elasticityQ46868332
Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excessQ47946574
Degenerative changes of porcine intervertebral disc induced by vertebral endplate injuries.Q48805542
Microtissue elasticity: measurements by atomic force microscopy and its influence on cell differentiation.Q50895194
Modified Pfirrmann grading system for lumbar intervertebral disc degeneration.Q51727876
Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix.Q51756063
Substrate stiffness together with soluble factors affects chondrocyte mechanoresponses.Q53463279
Investigation of the role ofANKHin ankylosing spondylitisQ57667840
The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast FunctionQ59843761
P407language of work or nameEnglishQ1860
P921main subjectcartilageQ502730
P304page(s)25401
P577publication date2016-05-04
P1433published inScientific ReportsQ2261792
P1476titleMatrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression
P478volume6

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cites work (P2860)
Q64071137Apoptotic bodies from endplate chondrocytes enhance the oxidative stress-induced mineralization by regulating PPi metabolism
Q90653505Mechanotransduction and cell biomechanics of the intervertebral disc
Q48218961The association of lumbar intervertebral disc calcification on plain radiographs with the UTE Disc Sign on MRI.
Q50698187[Effect of HBP-A on meniscal injury and pathological hypertrophy and calcification of the meniscus].

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