| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Maureen J Devlin | Q55542286 |
| P2093 | author name string | Clifford J Rosen | |
| Masanobu Kawai | |||
| P2860 | cites work | Oral Antidiabetic Agents | Q22241436 |
| Endocrine regulation of energy metabolism by the skeleton | Q22337453 | ||
| Association between serum osteocalcin and markers of metabolic phenotype | Q24644655 | ||
| Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum | Q24653502 | ||
| Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression | Q28269133 | ||
| Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2 | Q28284294 | ||
| Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men | Q28303182 | ||
| Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass | Q28505908 | ||
| Differential expression and activation of a family of murine peroxisome proliferator-activated receptors | Q28508118 | ||
| Leptin regulation of bone resorption by the sympathetic nervous system and CART | Q28589974 | ||
| Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone | Q28646319 | ||
| Pluripotential marrow cells produce adipocytes when transplanted into steroid-treated mice | Q30305680 | ||
| Leptin deficiency produces contrasting phenotypes in bones of the limb and spine | Q33198910 | ||
| Bone abnormalities in adolescent leptin-deficient mice | Q33246311 | ||
| Influence of insulin-like growth factor-1 and leptin on bone mineral content in healthy premenopausal women. | Q33261321 | ||
| Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers | Q73262130 | ||
| The effects of age and dietary restriction without nutritional supplementation on whole bone structural properties in C57BL/6J mice | Q73358541 | ||
| Growth deceleration and bone metabolism in nutritional dwarfing rats | Q74003960 | ||
| Protective effect of beta blockers in postmenopausal women: influence on fractures, bone density, micro and macroarchitecture | Q79836323 | ||
| Endocrine abnormalities in anorexia nervosa | Q81427842 | ||
| Bone status in an animal model of chronic sub-optimal nutrition: a morphometric, densitometric and mechanical study | Q81883933 | ||
| Phenotypic effects of calorie restriction and insulin-like growth factor-1 treatment on body composition and bone mineral density of C57BL/6 mice: implications for cancer prevention | Q81927947 | ||
| The effects of caloric restriction on skeletal growth | Q83289036 | ||
| Surface-specific effects of a PPARgamma agonist, darglitazone, on bone in mice | Q83945576 | ||
| Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin | Q61760408 | ||
| Risk of Fracture in Women with Type 2 Diabetes: the Women’s Health Initiative Observational Study | Q62673909 | ||
| Osteopenia in mice with genetic diabetes | Q68894623 | ||
| Bone mass in prepubertal boys is associated with a Gln223Arg amino acid substitution in the leptin receptor | Q33296951 | ||
| Caloric restriction decreases cortical bone mass but spares trabecular bone in the mouse skeleton: implications for the regulation of bone mass by body weight. | Q33330709 | ||
| The influence of ghrelin, adiponectin, and leptin on bone mineral density in healthy postmenopausal women | Q33382140 | ||
| Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial | Q33999757 | ||
| Leptin regulates bone formation via the sympathetic nervous system | Q34157988 | ||
| Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm | Q34165847 | ||
| Enhanced bone formation in lipodystrophic PPARgamma(hyp/hyp) mice relocates haematopoiesis to the spleen | Q34166268 | ||
| Recombinant human leptin in women with hypothalamic amenorrhea. | Q34345206 | ||
| Thiazolidinediones | Q34346862 | ||
| Playing with bone and fat. | Q34494766 | ||
| PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors | Q34546901 | ||
| PPAR-gamma regulates osteoclastogenesis in mice | Q34585778 | ||
| Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT). | Q34587610 | ||
| Opposite effects of leptin on bone metabolism: a dose-dependent balance related to energy intake and insulin-like growth factor-I pathway | Q34618658 | ||
| Leptin and the sympathetic connection of fat to bone | Q34699679 | ||
| The epidemiology of corticosteroid-induced osteoporosis: a meta-analysis | Q34961416 | ||
| Thiazolidinedione use and bone loss in older diabetic adults | Q35023205 | ||
| Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade | Q35642147 | ||
| Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat. | Q35745608 | ||
| Leptin, bone mass, and the thrifty phenotype | Q35881963 | ||
| Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology | Q35975460 | ||
| Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice | Q36014510 | ||
| Neuronal signaling and the regulation of bone remodeling | Q36244973 | ||
| Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins | Q36322457 | ||
| Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice | Q36516140 | ||
| The new field of neuroskeletal biology | Q36794388 | ||
| Serum leptin level is a regulator of bone mass | Q36855076 | ||
| TZDs and Bone: A Review of the Recent Clinical Evidence | Q36868437 | ||
| The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity | Q37023338 | ||
| Bone remodeling, energy metabolism, and the molecular clock | Q37051571 | ||
| A bone structural basis for fracture risk in diabetes | Q37061248 | ||
| Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo | Q37068600 | ||
| Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy. | Q37072802 | ||
| Molecular bases of the sympathetic regulation of bone mass | Q37092861 | ||
| Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I | Q37125989 | ||
| Marrow fat and the bone microenvironment: developmental, functional, and pathological implications | Q37172974 | ||
| Adrenergic control of bone remodeling and its implications for the treatment of osteoporosis. | Q37214296 | ||
| PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells | Q37349947 | ||
| Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis | Q37449744 | ||
| Association between serum leptin concentrations and bone mineral density, and biochemical markers of bone turnover in adult men. | Q38294887 | ||
| Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women | Q38296081 | ||
| Leptin is a potent stimulator of bone growth in ob/ob mice | Q38307707 | ||
| Leptin predicts BMD and bone resorption in older women but not older men: the Rancho Bernardo study | Q38312794 | ||
| Leptin regulates chondrocyte differentiation and matrix maturation during endochondral ossification | Q38323319 | ||
| Use of thiazolidinediones and fracture risk | Q38456774 | ||
| Association of leptin receptor polymorphisms Lys109Arg and Gln223Arg with serum leptin profile and bone mineral density in Korean women | Q38502472 | ||
| The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial | Q40247162 | ||
| Serum leptin level is a predictor of bone mineral density in postmenopausal women. | Q40654244 | ||
| Biochemical markers of bone turnover for the clinical investigation of osteoporosis | Q40891161 | ||
| Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2. | Q40941050 | ||
| Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes | Q40964024 | ||
| Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells | Q41155012 | ||
| Hypoxic adipocytes pattern early heterotopic bone formation. | Q42853387 | ||
| Role of serum leptin, insulin, and estrogen levels as potential mediators of the relationship between fat mass and bone mineral density in men versus women | Q43705369 | ||
| Troglitazone treatment increases bone marrow adipose tissue volume but does not affect trabecular bone volume in mice | Q43783873 | ||
| Mechanism and implications of brown adipose tissue proliferation in rats and monkeys treated with the thiazolidinedione darglitazone, a potent peroxisome proliferator-activated receptor-gamma agonist | Q44355513 | ||
| Beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong Osteoporosis Study | Q44690073 | ||
| Serotonin rising--the bone, brain, bowel connection | Q46098865 | ||
| Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus | Q46264486 | ||
| Leptin modulates both resorption and formation while preventing disuse-induced bone loss in tail-suspended female rats. | Q46449983 | ||
| Bone mineral density and bone turnover in relation to serum leptin, alpha-ketoglutarate and sex steroids in overweight and obese postmenopausal women. | Q46545552 | ||
| Effects of a beta-blocker on bone turnover in normal postmenopausal women: a randomized controlled trial | Q46585029 | ||
| Life-long caloric restriction reveals biphasic and dimorphic effects on bone metabolism in rodents. | Q46908250 | ||
| Leptin is a negative independent predictor of areal BMD and cortical bone size in young adult Swedish men. | Q47320172 | ||
| Selected contribution: Bone adaptation with aging and long-term caloric restriction in Fischer 344 x Brown-Norway F1-hybrid rats. | Q47830537 | ||
| Are serum leptin and the Gln223Arg polymorphism of the leptin receptor determinants of bone homeostasis in elderly men? | Q49085338 | ||
| Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women. | Q50544746 | ||
| The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis. | Q51488618 | ||
| Leptin reverses the inhibitory effect of caloric restriction on longitudinal growth. | Q51534065 | ||
| Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss. | Q53378273 | ||
| Dietary restriction does not adversely affect bone geometry and mechanics in rapidly growing male wistar rats. | Q53601820 | ||
| Estrogen receptor alpha gene polymorphisms Pvu II and Xba I influence association between leptin receptor gene polymorphism (Gln223Arg) and bone mineral density in young men. | Q53662278 | ||
| Body composition and bone measurements in intra-uterine growth retarded and early postnatally undernourished male and female rats at the age of 6 months: comparison with puberty. | Q53848795 | ||
| β-blocker use and risk of fractures in men and women from the general population: the MONICA/KORA Augsburg cohort study | Q57414627 | ||
| Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo | Q57533674 | ||
| Leptin Inhibits Osteoclast Generation | Q57533678 | ||
| The DREAM trial – Authors' reply | Q58040261 | ||
| What’s in a Name? In Search of Leptin’s Physiologic Role1 | Q59702481 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 365-372 | |
| P577 | publication date | 2009-05-26 | |
| P1433 | published in | Nature Reviews Rheumatology | Q2107227 |
| P1476 | title | Fat targets for skeletal health | |
| P478 | volume | 5 |
| Q35646073 | A high-fat diet induces bone loss in mice lacking the Alox5 gene |
| Q37793535 | Adiposity hormones and dementia |
| Q33947244 | An adenosine receptor-Krüppel-like factor 4 protein axis inhibits adipogenesis |
| Q51364827 | Association between obesity, metabolic risks and serum osteocalcin level in postmenopausal women. |
| Q38617812 | Association between serum osteocalcin and body mass index: a systematic review and meta-analysis. |
| Q44469008 | Association between the SPRY1 gene polymorphism and obesity-related traits and osteoporosis in Korean women. |
| Q30429441 | Associations between serum leptin level and bone turnover in kidney transplant recipients |
| Q39281698 | Biophysical Stimulation for Bone Regeneration |
| Q45716063 | Bone marrow composition, diabetes, and fracture risk: more bad news for saturated fat. |
| Q33700277 | Bone marrow fat accumulation accelerated by high fat diet is suppressed by exercise. |
| Q34103989 | Caloric restriction leads to high marrow adiposity and low bone mass in growing mice |
| Q36181331 | Circulating osteocalcin level is not associated with incident type 2 diabetes in middle-aged male subjects: mean 8.4-year retrospective follow-up study |
| Q37518446 | Daily leptin blunts marrow fat but does not impact bone mass in calorie-restricted mice |
| Q90372908 | Dairy product intake decreases bone resorption following a 12-week diet and exercise intervention in overweight and obese adolescent girls |
| Q38087556 | Diabetes mellitus and osteoporosis |
| Q50443339 | Effects of risedronate on bone marrow adipocytes in postmenopausal women |
| Q37139483 | Efficient isolation of bone marrow adipocyte progenitors by silica microbeads incubation. |
| Q34161867 | Emerging therapeutic opportunities for skeletal restoration |
| Q36044509 | Ethnic and sex differences in bone marrow adipose tissue and bone mineral density relationship |
| Q42801551 | Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss. |
| Q28397345 | Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies |
| Q36103498 | Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice |
| Q35105396 | Hormone-sensitive lipase-knockout mice maintain high bone density during aging |
| Q58381286 | Importance of fat mass and lean mass on bone health in men: the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV) |
| Q36753806 | Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice |
| Q39003578 | Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1. |
| Q37994636 | Intercellular cross-talk among bone cells: new factors and pathways. |
| Q91776026 | Lipoatrophy and metabolic disturbance in mice with adipose-specific deletion of kindlin-2 |
| Q37319591 | Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARγ. |
| Q35403424 | Marrow fat metabolism is linked to the systemic energy metabolism |
| Q36883559 | Mesenchymal stem cells, aging and regenerative medicine |
| Q93048580 | Metal Nanoparticles Released from Dental Implant Surfaces: Potential Contribution to Chronic Inflammation and Peri-Implant Bone Loss |
| Q59137309 | Mettl3-mediated mA RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis |
| Q51162640 | Micro-architectural changes in cancellous bone differ in female and male C57BL/6 mice with high-fat diet-induced low bone mineral density. |
| Q34132327 | Minireview: A skeleton in serotonin's closet? |
| Q35807252 | New mutations at the imprinted Gnas cluster show gene dosage effects of Gsα in postnatal growth and implicate XLαs in bone and fat metabolism but not in suckling |
| Q30423863 | Nocturnin: a circadian target of Pparg-induced adipogenesis. |
| Q35674683 | Novel insights into the relationship between diabetes and osteoporosis |
| Q59797072 | Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling |
| Q38076660 | Obesity and fracture in men and women: an epidemiologic perspective |
| Q53703048 | Obesity, Metabolic Syndrome, and Musculoskeletal Disease: Common Inflammatory Pathways Suggest a Central Role for Loss of Muscle Integrity. |
| Q34388316 | Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice |
| Q37266142 | Osteoblast-targeted suppression of PPARγ increases osteogenesis through activation of mTOR signaling. |
| Q35765440 | Osteocalcin and the Regulation of Glucose Metabolism |
| Q40848790 | Peroxisome proliferator-activated receptor gamma/signal transducers and activators of transcription 5A pathway plays a key factor in adipogenesis of human bone marrow-derived stromal cells and 3T3-L1 preadipocytes |
| Q33520403 | RAGE supports parathyroid hormone-induced gains in femoral trabecular bone |
| Q47406102 | Relationships between preptin and osteocalcin in obese, overweight, and normal weight adults. |
| Q53374383 | Serum leptin levels are associated with the presence of syndesmophytes in male patients with ankylosing spondylitis. |
| Q34129927 | Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome |
| Q34619735 | Skeletal aging and the adipocyte program: New insights from an "old" molecule |
| Q26738893 | The Role of Bone Marrow Microenvironment in Governing the Balance between Osteoblastogenesis and Adipogenesis |
| Q92008613 | The Role of Obesity in Pediatric Orthopedics |
| Q84409000 | The effects of low dose parathyroid hormone on lumbar vertebrae in a rat model for chronic alcohol abuse |
| Q36536852 | The effects of thiazolidinediones on human bone marrow stromal cell differentiation in vitro and in thiazolidinedione-treated patients with type 2 diabetes |
| Q35636353 | The role of osteocalcin in human glucose metabolism: marker or mediator? |
| Q38225482 | Underweight, overweight, and pediatric bone fragility: impact and management |
| Q31160528 | Vertebral bone marrow fat, bone mineral density and diabetes: The Osteoporotic Fractures in Men (MrOS) study |
| Q35202573 | Why does starvation make bones fat? |
| Q87541341 | [Interaction between bone, fat and insulin] |
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