Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes

scientific article published on 2 January 2013

Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1530/JOE-12-0356
P932PMC publication ID3665007
P698PubMed publication ID23086140

P50authorEva FeldmanQ5415042
Lucy M HinderQ57023938
Subramaniam PennathurQ87965108
Anuradha Vivekanandan-GiriQ125193959
P2093author name stringLisa L McLean
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Hyperglycemia alters the schwann cell mitochondrial proteome and decreases coupled respiration in the absence of superoxide productionQ33571909
Mitochondrial respiratory chain dysfunction in dorsal root ganglia of streptozotocin-induced diabetic rats and its correction by insulin treatmentQ33750650
Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stressQ33991775
Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanismsQ34104944
Superoxide radical and iron modulate aconitase activity in mammalian cellsQ34312112
Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic RatsQ34448722
Transcriptional profiling of diabetic neuropathy in the BKS db/db mouse: a model of type 2 diabetes.Q35063229
Quantitative analysis of amino Acid oxidation markers by tandem mass spectrometryQ35173711
Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes.Q35184731
New insights into the mechanisms of diabetic neuropathy.Q35813649
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Diabetic neuropathy--a reviewQ36840602
Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J miceQ36972748
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Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1.Q37360464
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complicationsQ37373683
Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.Q37466088
Hyperlipidemia: a new therapeutic target for diabetic neuropathyQ37659233
Diabetic neuropathy: cellular mechanisms as therapeutic targetsQ37930962
Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathyQ39540319
Reducing time and increasing sensitivity in sample preparation for adherent mammalian cell metabolomicsQ39566477
Palmitate induces apoptosis in Schwann cells via both ceramide-dependent and independent pathwaysQ39621875
Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalystQ39703468
Diabetes-induced nitrative stress in the retina, and correction by aminoguanidineQ40738869
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunctionQ41629495
A multicentre study of the prevalence of diabetic peripheral neuropathy in the United Kingdom hospital clinic populationQ44908082
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen speciesQ45005902
Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase.Q45050762
Short-term hyperglycemia produces oxidative damage and apoptosis in neuronsQ45242262
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.Q46368551
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.Q46458495
Analysis of glucose metabolism in diabetic rat retinasQ46870099
Skin denervation in type 2 diabetes: correlations with diabetic duration and functional impairments.Q47645291
Limitation of glycolysis by hexokinase in rat brain synaptosomes during intense ion pumpingQ48965403
Neurons undergo apoptosis in animal and cell culture models of diabetes.Q52536719
Expression of hexokinase isoforms in the dorsal root ganglion of the adult rat and effect of experimental diabetesQ62056174
In Vitro Studies of the Substrates for Energy Production and the Effects of Insulin on Glucose Utilization in the Neural Components of Peripheral NerveQ66924469
Inactivation-reactivation of aconitase in Escherichia coli. A sensitive measure of superoxide radicalQ67847310
Altered axonal transport of cytoskeletal proteins in the mutant diabetic mouseQ68940896
Effects of acute, subacute, and chronic diabetes on carbohydrate and energy metabolism in rat sciatic nerve. Relation to mechanisms of peripheral neuropathyQ72554918
Axonal transport of acetylcholinesterase in the diabetic mutant mouseQ72714458
Tricarboxylic acid cycle in rat brain synaptosomes. Fluxes and interactions with aspartate aminotransferase and malate/aspartate shuttleQ72808469
Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathyQ73060857
Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention studyQ73092762
Effect of dietary taurine supplementation on GSH and NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic precataractous lensQ74586633
Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipidsQ77402563
Diabetes-induced changes in lens antioxidant status, glucose utilization and energy metabolism: effect of DL-alpha-lipoic acidQ77731036
Diabetic neuropathyQ80550534
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttype 2 diabetesQ3025883
murine modelQ122890741
P304page(s)1-11
P577publication date2013-01-02
P1433published inJournal of EndocrinologyQ6295150
P1476titleDecreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes
P478volume216

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