Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege

scientific article published on April 2010

Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3109/08830180903349669
P932PMC publication ID3671384
P698PubMed publication ID20367139
P5875ResearchGate publication ID43022186

P2093author name stringBabak Baban
Lei Huang
Andrew L Mellor
Burles A Johnson
P2860cites workIncreased synthesis of indoleamine-2,3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancerQ56786153
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cellsQ56902123
Activation requirements for the induction of CD4+CD25+ T cell suppressor functionQ56903555
When ligand becomes receptor--tolerance via B7 signaling on DCsQ56904184
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergyQ58855390
Mucosal CD8alpha+ DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory propertiesQ73196801
Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferationQ73567305
Dendritic cells have the option to express IDO-mediated suppression or notQ81474897
Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunityQ84080100
Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in miceQ24288997
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and miceQ24305475
Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophanQ24328949
Prevention of allogeneic fetal rejection by tryptophan catabolismQ24336018
Essential role for CD103 in the T cell-mediated regulation of experimental colitisQ24646106
Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenaseQ28115622
Inhibition of T cell proliferation by macrophage tryptophan catabolismQ28142922
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenaseQ28204166
Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specificQ28254589
Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responsesQ28283999
Induction of IDO by bacille Calmette-Guérin is responsible for development of murine depressive-like behaviorQ28508390
Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammationQ28591402
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.Q30374900
Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans.Q33361113
Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancerQ33482453
Anti-CTLA-4 treatment induces IL-10-producing ICOS+ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitisQ34048386
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.Q34394487
Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape.Q34655953
The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generationQ34657284
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.Q34657500
A sense of tumour for the immune systemQ34842108
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infectionQ35131219
HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cellsQ35751070
Inhibition of experimental asthma by indoleamine 2,3-dioxygenaseQ35835456
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.Q35835489
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenaseQ35925641
3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosisQ36276917
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic miceQ36399304
Dendritic cells in a mature age.Q36475977
A historical perspective on immunological privilegeQ36593722
The importance of regional lymph nodes for mucosal toleranceQ36593742
Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponsesQ44134414
Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenaseQ44135171
T cell apoptosis by tryptophan catabolismQ44137068
CTLA-4-Ig regulates tryptophan catabolism in vivo.Q44170968
Cutting edge: induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion.Q44539418
CDllc+ cells modulate pulmonary immune responses by production of indoleamine 2,3-dioxygenaseQ44575994
Modulation of tryptophan catabolism by regulatory T cells.Q44632333
Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells.Q44807466
Human epidermal langerhans cells express the immunoregulatory enzyme indoleamine 2,3-dioxygenaseQ44971540
Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenaseQ45047397
Induction of immunosuppressive molecules and regulatory T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse model of liver cancerQ45871945
Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells.Q45922663
Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression.Q45947449
Tryptophan deprivation induces inhibitory receptors ILT3 and ILT4 on dendritic cells favoring the induction of human CD4+CD25+ Foxp3+ T regulatory cells.Q45964911
Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis.Q46030942
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.Q46490849
Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant.Q46499878
Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammationQ46531302
A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligationQ46557704
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cellsQ46734158
Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.Q46737044
Novel action of indoleamine 2,3-dioxygenase attenuating acute lung allograft injuryQ46809300
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.Q46815296
IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic cellsQ46941757
CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibitionQ46979779
The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse.Q53524050
Tryptophan catabolism in IDO+ plasmacytoid dendritic cells.Q36789443
Indoleamine 2,3-dioxygenase and tumor-induced toleranceQ36809762
IDO expression in the brain: a double-edged swordQ36861514
IDO activates regulatory T cells and blocks their conversion into Th17-like T cellsQ36914732
Creating immune privilege: active local suppression that benefits friends, but protects foes.Q37026641
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesisQ37081582
The importance of NAD in multiple sclerosisQ37118012
Th17 cell differentiation: the long and winding roadQ37133442
Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responsesQ37157936
Stem cells ameliorate EAE via an indoleamine 2,3-dioxygenase (IDO) mechanismQ37189921
Clinical relevance of indoleamine 2,3-dioxygenase for alloimmunity and transplantationQ37228240
Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.Q37234611
Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.Q37268984
T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenaseQ37334065
The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunityQ37340475
Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.Q37347671
Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolismQ37349845
Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapyQ37352554
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?Q37492248
Targeting indoleamine 2,3-dioxygenase (IDO) to counteract tumour-induced immune dysfunction: from biochemistry to clinical development.Q37516009
Type II collagen oral tolerance; mechanism and role in collagen-induced arthritis and rheumatoid arthritisQ37583662
Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signalingQ38319700
Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma.Q38450454
Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinomaQ39814919
Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancerQ39843619
Expression and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular carcinomaQ39988114
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolismQ39991104
Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinomaQ40041177
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cellsQ40082326
Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cellsQ40197317
Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenaseQ40495420
Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell divisionQ40686234
Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.Q42484177
Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells.Q42509333
CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenaseQ42876261
Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.Q43514619
IL-6 inhibits the tolerogenic function of CD8 alpha+ dendritic cells expressing indoleamine 2,3-dioxygenaseQ43664739
Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells.Q43769122
Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitisQ44088414
P433issue2
P921main subjectdendritic cellQ506253
P304page(s)133-155
P577publication date2010-04-01
P1433published inInternational Reviews of ImmunologyQ6052764
P1476titleDendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege
P478volume29

Reverse relations

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