| scholarly article | Q13442814 |
| P50 | author | Anne Joutel | Q47155789 |
| Emmanuel Cognat | Q58428999 | ||
| Joelle Vinh | Q63806414 | ||
| P2093 | author name string | Céline Baron-Menguy | |
| Marie Monet-Leprêtre | |||
| Iman Haddad | |||
| Valérie Domenga-Denier | |||
| Meriem Riani | |||
| Claire Dussaule | |||
| Maï Fouillot-Panchal | |||
| P2860 | cites work | The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients | Q24629786 |
| A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2 | Q28185858 | ||
| Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy | Q28236562 | ||
| Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients | Q28255796 | ||
| Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges | Q28287345 | ||
| Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia | Q28294011 | ||
| A model for random sampling and estimation of relative protein abundance in shotgun proteomics | Q29547316 | ||
| The canonical Notch signaling pathway: unfolding the activation mechanism | Q29547725 | ||
| Structure and function of matrix metalloproteinases and TIMPs | Q30014818 | ||
| Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain | Q30487788 | ||
| Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease | Q30492865 | ||
| Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization | Q30497541 | ||
| Evaluation of the efficiency of in-gel digestion of proteins by peptide isotopic labeling and MALDI mass spectrometry | Q30716557 | ||
| Cadasil | Q33470786 | ||
| Increased neovascularization in mice lacking tissue inhibitor of metalloproteinases-3. | Q33808182 | ||
| Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling Pathway | Q33909665 | ||
| Skin biopsy immunostaining with a Notch3 monoclonal antibody for CADASIL diagnosis | Q34106491 | ||
| Notch3 Is Critical for Proper Angiogenesis and Mural Cell Investment | Q34168399 | ||
| Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy | Q34305487 | ||
| Vitronectin in vascular context: facets of a multitalented matricellular protein | Q34631318 | ||
| Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease | Q35008186 | ||
| Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby's fundus dystrophy or retinitis pigmentosa | Q35303077 | ||
| Genetics of ischaemic stroke | Q36713912 | ||
| Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities. | Q36805538 | ||
| Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients | Q37158175 | ||
| Amyloid in neurodegenerative diseases: friend or foe? | Q37860535 | ||
| Notch signalling in smooth muscle cells during development and disease | Q37977827 | ||
| Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions | Q39610788 | ||
| CADASIL mutations enhance spontaneous multimerization of NOTCH3. | Q39856502 | ||
| Identification of the extracellular matrix (ECM) binding motifs of tissue inhibitor of metalloproteinases (TIMP)-3 and effective transfer to TIMP-1. | Q40254634 | ||
| Notch3 is required for arterial identity and maturation of vascular smooth muscle cells | Q40408474 | ||
| Bidirectional encroachment of collagen into the tunica media in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy | Q42013247 | ||
| CADASIL-associated Notch3 mutations have differential effects both on ligand binding and ligand-induced Notch3 receptor signaling through RBP-Jk | Q42825763 | ||
| Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy | Q42855085 | ||
| Evaluation of diagnostic NOTCH3 immunostaining in CADASIL. | Q47900651 | ||
| The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo | Q48256255 | ||
| Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy. | Q48323994 | ||
| Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy | Q56502592 | ||
| Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL | Q57187397 | ||
| Spectrum of mutations in biopsy-proven CADASIL: implications for diagnostic strategies | Q80357378 | ||
| Co-aggregate formation of CADASIL-mutant NOTCH3: a single-particle analysis | Q84235340 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | Pt 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | extracellular matrix | Q193825 |
| P304 | page(s) | 1830-1845 | |
| P577 | publication date | 2013-05-06 | |
| P1433 | published in | Brain | Q897386 |
| P1476 | title | Abnormal recruitment of extracellular matrix proteins by excess Notch3 ECD: a new pathomechanism in CADASIL | |
| P478 | volume | 136 |
| Q36065466 | A local complement response by RPE causes early-stage macular degeneration. |
| Q57811524 | Altered dynamics of neurovascular coupling in CADASIL |
| Q54384496 | Alzheimer's disease and CADASIL are heritable, adult-onset dementias that both involve damaged small blood vessels. |
| Q37399561 | Archetypal NOTCH3 mutations frequent in public exome: implications for CADASIL. |
| Q64106545 | Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects |
| Q30861866 | CADASIL and CARASIL. |
| Q38672393 | CADASIL mutant NOTCH3(R90C) decreases the viability of HS683 oligodendrocytes via apoptosis |
| Q38663098 | CADASIL: Treatment and Management Options. |
| Q37694369 | CADASIL: Ultrastructural insights into the morphology of granular osmiophilic material. |
| Q30574731 | Cerebral small vessel disease: insights and opportunities from mouse models of collagen IV-related small vessel disease and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy |
| Q57456322 | Cerebrovascular disorders associated with genetic lesions |
| Q95840655 | Clinical and Genetic Aspects of CADASIL |
| Q37105606 | Clusterin/Apolipoprotein J immunoreactivity is associated with white matter damage in cerebral small vessel diseases |
| Q36593206 | Consensus statement for diagnosis of subcortical small vessel disease |
| Q37620563 | Crosstalk between cerebral endothelium and oligodendrocyte |
| Q97419421 | Disturbed balance in the expression of MMP9 and TIMP3 in cerebral amyloid angiopathy-related intracerebral haemorrhage |
| Q37643585 | Endothelial cell-oligodendrocyte interactions in small vessel disease and aging |
| Q93102418 | Genetic Factors of Cerebral Small Vessel Disease and Their Potential Clinical Outcome |
| Q38433566 | Genetic factors in cerebral small vessel disease and their impact on stroke and dementia |
| Q42579948 | Homozygous NOTCH3 null mutation and impaired NOTCH3 signaling in recessive early-onset arteriopathy and cavitating leukoencephalopathy |
| Q47155731 | Increased Notch3 Activity Mediates Pathological Changes in Structure of Cerebral Arteries. |
| Q38213076 | Interpretation of NOTCH3 mutations in the diagnosis of CADASIL. |
| Q26770783 | Investigating Human Neurovascular Coupling Using Functional Neuroimaging: A Critical Review of Dynamic Models |
| Q42957412 | Latent NOTCH3 epitopes unmasked in CADASIL and regulated by protein redox state |
| Q92857334 | Lenticulostriate Arteries and Basal Ganglia Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy, a High-Field MRI Study |
| Q41447018 | Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics |
| Q64264903 | Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells |
| Q38513520 | Monogenic causes of stroke: now and the future |
| Q90625242 | Multifaceted roles of pericytes in central nervous system homeostasis and disease |
| Q46795621 | Notch Signaling in Development, Tissue Homeostasis, and Disease |
| Q90631800 | Notch3 in Development, Health and Disease |
| Q41493863 | Perivascular spaces, glymphatic dysfunction, and small vessel disease |
| Q36593214 | Perturbations of the cerebrovascular matrisome: A convergent mechanism in small vessel disease of the brain? |
| Q35128837 | Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease. |
| Q91669321 | Proteostasis in Cerebral Small Vessel Disease |
| Q35951724 | R54C Mutation of NOTCH3 Gene in the First Rungus Family with CADASIL. |
| Q37713541 | Reducing Timp3 or vitronectin ameliorates disease manifestations in CADASIL mice. |
| Q34571315 | Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits |
| Q38150763 | Small vessel disease and memory loss: what the clinician needs to know to preserve patients' brain health. |
| Q53827519 | Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. |
| Q57168304 | Sorsby fundus dystrophy: Insights from the past and looking to the future |
| Q36666116 | Targeting of exon VI-skipping human RGR-opsin to the plasma membrane of pigment epithelium and co-localization with terminal complement complex C5b-9 |
| Q92256310 | The Diverse Roles of TIMP-3: Insights into Degenerative Diseases of the Senescent Retina and Brain |
| Q36417190 | The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation |
| Q34544980 | The pathobiology of vascular malformations: insights from human and model organism genetics |
| Q35175576 | The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3 |
| Q39970746 | Therapeutic NOTCH3 cysteine correction in CADASIL using exon skipping: in vitro proof of concept. |
| Q38208211 | Therapeutic modulation of Notch signalling--are we there yet? |
| Q89973008 | Thiol-mediated and catecholamine-enhanced multimerization of a cerebrovascular disease enriched fragment of NOTCH3 |
| Q34021090 | Vascular accumulation of the small leucine-rich proteoglycan decorin in CADASIL. |
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