Microwave-induced nucleophilic [18F]fluorination on aromatic rings: synthesis and effect of halogen on [18F]fluoride substitution of meta-halo (F, Cl, Br, I)-benzonitrile derivatives

scientific article published on 10 March 2008

Microwave-induced nucleophilic [18F]fluorination on aromatic rings: synthesis and effect of halogen on [18F]fluoride substitution of meta-halo (F, Cl, Br, I)-benzonitrile derivatives is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.APRADISO.2008.03.003
P932PMC publication ID2553010
P698PubMed publication ID18417350

P2093author name stringNing Guo
Gilles Tamagnan
Ronald R Price
Ronald M Baldwin
David Alagille
P2860cites workCopper-catalyzed halogen exchange in aryl halides: an aromatic Finkelstein reactionQ28217113
Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomographyQ34447299
Fluorinated tracers for imaging cancer with positron emission tomographyQ35829825
Controlled microwave heating in modern organic synthesis.Q35959976
Molecular nuclear imaging: the radiopharmaceuticals (review).Q36115523
Prostate cancer PET bioprobes: synthesis of [18F]-radiolabeled hydroxyflutamide derivativesQ40401095
Synthesis and in vitro evaluation of 18F- and 19F-labeled insulin: a new radiotracer for PET-based molecular imaging studiesQ42805074
Synthesis of a [6-pyridinyl-18F]-labelled fluoro derivative of WAY-100635 as a candidate radioligand for brain 5-HT1A receptor imaging with PET.Q44466648
Radiolabelling of isopeptide N epsilon-(gamma-glutamyl)-L-lysine by conjugation with N-succinimidyl-4-[18F]fluorobenzoateQ44523672
Synthesis of a [2-pyridinyl-18F]-labelled fluoro derivative of (-)-cytisine as a candidate radioligand for brain nicotinic alpha4beta2 receptor imaging with PET.Q44671735
5-substituted derivatives of 6-halogeno-3-((2-(S)-azetidinyl)methoxy)pyridine and 6-halogeno-3-((2-(S)-pyrrolidinyl)methoxy)pyridine with low picomolar affinity for alpha4beta2 nicotinic acetylcholine receptor and wide range of lipophilicity: potentQ44871626
Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomographyQ45274903
Radiosynthesis of .sigma. receptor ligands for positron emission tomography: carbon-11 and fluorine-18 labeled guanidinesQ46185633
Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracersQ46415856
Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterizationQ46634311
Synthesis, affinity and specificity of 18F-setoperone, a potential ligand for in-vivo imaging of cortical serotonin receptorsQ48140199
Synthesis and in vivo evaluation of 18F-desbromo-DuP-697 as a PET tracer for cyclooxygenase-2 expressionQ48178690
Synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor PET imagingQ48224836
Synthesis, biodistribution and micro-PET imaging of radiolabeled antimitotic agent T138067 analogues.Q53630762
Rapid microwave-assisted fluorination yielding novel 5′-deoxy-5′-fluorouridine derivativesQ57708498
Meta Halogenation of 1,3-Disubstituted Arenes via Iridium-Catalyzed Arene BorylationQ64387629
P433issue10
P304page(s)1396-1402
P577publication date2008-03-10
P1433published inApplied Radiation and IsotopesQ541448
P1476titleMicrowave-induced nucleophilic [18F]fluorination on aromatic rings: synthesis and effect of halogen on [18F]fluoride substitution of meta-halo (F, Cl, Br, I)-benzonitrile derivatives
P478volume66