review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Christian Herr | Q47171551 |
P2093 | author name string | Robert Bals | |
Renat Shaykhiev | |||
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PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx | Q24294958 | ||
Structural and functional characterization of hBD-1(Ser35), a peptide deduced from a DEFB1 polymorphism | Q24299270 | ||
Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina | Q24302168 | ||
Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin | Q24305367 | ||
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis | Q24306578 | ||
Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense | Q24310770 | ||
The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes | Q24336630 | ||
Single-nucleotide polymorphisms (SNPs) in human beta-defensin 1: high-throughput SNP assays and association with Candida carriage in type I diabetics and nondiabetic controls | Q24338413 | ||
Discovery of five conserved beta -defensin gene clusters using a computational search strategy | Q24529856 | ||
Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster | Q24532826 | ||
Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity | Q24556650 | ||
Defensins. Natural peptide antibiotics of human neutrophils | Q24563852 | ||
Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung | Q24564556 | ||
Human beta-defensin-1: an antimicrobial peptide of urogenital tissues | Q24564659 | ||
LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells | Q24675869 | ||
The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface | Q24680172 | ||
Isolation of human beta-defensin-4 in lung tissue and its increase in lower respiratory tract infection | Q24814433 | ||
Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes | Q27733422 | ||
Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3 | Q28117302 | ||
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense | Q28145389 | ||
Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia | Q28145673 | ||
Antimicrobial and Protease Inhibitory Functions of the Human Cathelicidin (hCAP18/LL-37) Prosequence | Q28201013 | ||
Discovery of new human beta-defensins using a genomics-based approach | Q28202377 | ||
Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction | Q28204611 | ||
Mediators of innate immunity that target immature, but not mature, dendritic cells induce antitumor immunity when genetically fused with nonimmunogenic tumor antigens | Q28206241 | ||
Kostmann syndrome and severe congenital neutropenia | Q28214981 | ||
Human neutrophil defensin and serpins form complexes and inactivate each other | Q28235442 | ||
A peptide antibiotic from human skin | Q28242199 | ||
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection | Q28244066 | ||
Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3 | Q28258765 | ||
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils | Q28277848 | ||
hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules | Q28293594 | ||
hBD-1: a novel beta-defensin from human plasma | Q28294850 | ||
Defensins | Q28297042 | ||
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response | Q28298985 | ||
Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis | Q28303994 | ||
Human airway epithelia express a beta-defensin | Q28305968 | ||
Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa | Q28492663 | ||
beta-Defensin 1 contributes to pulmonary innate immunity in mice | Q28593573 | ||
Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway | Q28612022 | ||
Activity of alpha- and theta-defensins against primary isolates of HIV-1 | Q28612167 | ||
Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides | Q30754864 | ||
Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins | Q30959530 | ||
Theta-defensins: cyclic antimicrobial peptides produced by binary ligation of truncated alpha-defensins | Q30976126 | ||
Evaluation of the effects of peptide antibiotics human beta-defensins-1/-2 and LL-37 on histamine release and prostaglandin D(2) production from mast cells | Q43572155 | ||
Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kappaB transcription factor family | Q43829936 | ||
The antimicrobial activity of the cathelicidin LL37 is inhibited by F-actin bundles and restored by gelsolin | Q44296193 | ||
Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro | Q44519283 | ||
Elevated BALF concentrations of alpha- and beta-defensins in patients with pulmonary alveolar proteinosis | Q44768578 | ||
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release | Q44832287 | ||
Neutrophil defensins stimulate the release of cytokines by airway epithelial cells: modulation by dexamethasone | Q45711894 | ||
Salt-independent abnormality of antimicrobial activity in cystic fibrosis airway surface fluid | Q45878847 | ||
Purification and characterization of defensins from cystic fibrosis sputum | Q46165359 | ||
Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. | Q46283394 | ||
α-Defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors | Q46627893 | ||
An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7. | Q46956198 | ||
Cytokine milieu of atopic dermatitis, as compared to psoriasis, skin prevents induction of innate immune response genes | Q47640250 | ||
Identification of hBD-3 in respiratory tract and serum: the increase in pneumonia | Q47645209 | ||
Elevated levels of antimicrobial peptides in bronchoalveolar lavage fluid in patients with chronic eosinophilic pneumonia | Q47665173 | ||
Polymorphisms of the human beta-defensin-1 gene. | Q47844333 | ||
Beta-defensins and LL-37 in bronchoalveolar lavage fluid of patients with cystic fibrosis | Q47917688 | ||
Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense | Q47922120 | ||
Rhinovirus increases human beta-defensin-2 and -3 mRNA expression in cultured bronchial epithelial cells. | Q51660498 | ||
Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection. | Q51721609 | ||
Expression of human beta defensin (HBD-1 and HBD-2) mRNA in nasal epithelia of adult cystic fibrosis patients, healthy individuals, and individuals with acute cold. | Q51727354 | ||
Genetic variants of human beta-defensin-1 and chronic obstructive pulmonary disease. | Q51728482 | ||
The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands. | Q51978562 | ||
Elevated concentrations of defensins in bronchoalveolar lavage fluid in diffuse panbronchiolitis. | Q53954955 | ||
Deficiency of antibacterial peptides in patients with morbus Kostmann: an observation study. | Q55036173 | ||
Interaction of antimicrobial peptides with bacterial polysaccharides from lung pathogens | Q57275273 | ||
Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication | Q39375601 | ||
Allergic airway inflammation inhibits pulmonary antibacterial host defense | Q40254150 | ||
Mechanisms of cell death induced by the neutrophil antimicrobial peptides alpha-defensins and LL-37. | Q40284042 | ||
Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure | Q40407531 | ||
Cathelicidins: a novel protein family with a common proregion and a variable C‐terminal antimicrobial domain | Q40432691 | ||
Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells. | Q40517650 | ||
Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo | Q40575765 | ||
The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes | Q40581590 | ||
The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor. | Q40609292 | ||
Modulation of human beta-defensin-2 transcription in pulmonary epithelial cells by lipopolysaccharide-stimulated mononuclear phagocytes via proinflammatory cytokine production | Q40656602 | ||
Molecular mechanisms underlying human beta-defensin-2 gene expression in a human airway cell line (LC2/ad). | Q40691658 | ||
Endogenous antimicrobial peptides and skin infections in atopic dermatitis | Q40698186 | ||
Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein | Q40763230 | ||
Gene-encoded peptide antibiotics and the concept of innate immunity: an update review | Q40845689 | ||
Antimicrobial peptides of vertebrates | Q41729805 | ||
Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. | Q42453950 | ||
Plasma and BAL fluid concentrations of antimicrobial peptides in patients with Mycobacterium avium-intracellulare infection | Q43570690 | ||
Neutrophil elastase up-regulates human beta-defensin-2 expression in human bronchial epithelial cells. | Q31148144 | ||
Antimicrobial peptides in mammalian and insect host defence | Q33536544 | ||
Diffuse panbronchiolitis--pathophysiology and treatment mechanisms | Q33843948 | ||
Transfer of a cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model | Q33849677 | ||
A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins | Q33876954 | ||
The θ-Defensin, Retrocyclin, Inhibits HIV-1 Entry | Q33973525 | ||
Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. | Q34011178 | ||
Innate antimicrobial peptide protects the skin from invasive bacterial infection | Q34102960 | ||
Characterization of the mouse beta defensin 1, Defb1, mutant mouse model. | Q34124317 | ||
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin | Q34186394 | ||
MEF up-regulates human beta-defensin 2 expression in epithelial cells. | Q34304777 | ||
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds | Q34326463 | ||
Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel | Q34359011 | ||
Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells | Q34407161 | ||
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. | Q34534186 | ||
Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair | Q34551373 | ||
Cathelicidins: microbicidal activity, mechanisms of action, and roles in innate immunity | Q34574499 | ||
LL-37 protects rats against lethal sepsis caused by gram-negative bacteria | Q34648782 | ||
Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. | Q34732912 | ||
Mechanisms for induction of acquired host immunity by neutrophil peptide defensins | Q34835899 | ||
CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition | Q35020718 | ||
Crohn's disease: a defensin deficiency syndrome? | Q35168862 | ||
Raised plasma concentrations of alpha-defensins in patients with idiopathic pulmonary fibrosis | Q35535282 | ||
Increased concentrations of human beta-defensins in plasma and bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis | Q35535921 | ||
Innate immunity in the lung: how epithelial cells fight against respiratory pathogens | Q35673699 | ||
Alarmins: chemotactic activators of immune responses | Q36162859 | ||
The role of bacteria in airway inflammation in exacerbations of chronic obstructive pulmonary disease | Q36462964 | ||
Defensins in innate antiviral immunity | Q36488755 | ||
Production of beta-defensins by human airway epithelia | Q36758628 | ||
Synthesis and solution structure of the antimicrobial peptide protegrin-1. | Q36800785 | ||
A link between chronic asthma and chronic infection | Q37874435 | ||
Bacterial phosphorylcholine decreases susceptibility to the antimicrobial peptide LL-37/hCAP18 expressed in the upper respiratory tract. | Q38315085 | ||
Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37. | Q38362260 | ||
Activation of a Src-dependent Raf-MEK1/2-ERK signaling pathway is required for IL-1alpha-induced upregulation of beta-defensin 2 in human middle ear epithelial cells | Q38522615 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1449-1461 | |
P577 | publication date | 2007-09-01 | |
P1433 | published in | Expert Opinion on Biological Therapy | Q5421201 |
P1476 | title | The role of cathelicidin and defensins in pulmonary inflammatory diseases | |
P478 | volume | 7 |
Q37777543 | Aerobiology and inhalation exposure to biological select agents and toxins. |
Q42529424 | Antimicrobial lipids: novel innate defense molecules are elevated in sinus secretions of patients with chronic rhinosinusitis |
Q34475611 | Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis |
Q38846409 | Bacteria in COPD; their potential role and treatment. |
Q33962245 | Childhood asthma may be a consequence of vitamin D deficiency |
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Q38066985 | Effects of vitamin D on immune disorders with special regard to asthma, COPD and autoimmune diseases: a short review |
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Q37052179 | Hypothesis--ultraviolet-B irradiance and vitamin D reduce the risk of viral infections and thus their sequelae, including autoimmune diseases and some cancers |
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