Physiology and pharmacology of corticotropin-releasing factor

scientific article published on December 1, 1991

Physiology and pharmacology of corticotropin-releasing factor is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P953full work available at URLhttp://pharmrev.aspetjournals.org/cgi/content/abstract/43/4/425
P698PubMed publication ID1775506

P50authorCharles NemeroffQ5081224
P2093author name stringOwens MJ
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
physiologyQ521
P304page(s)425-473
P577publication date1991-12-01
P1433published inPharmacological ReviewsQ2085079
P1476titlePhysiology and pharmacology of corticotropin-releasing factor
P478volume43

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cites work (P2860)
Q86419589A Mutagenic Primer Assay for Genotyping of the CRHR1 Gene Rare Variant rs1876828 (A/G) in Asians: A Cost-Effective SNP Typing
Q34577659A novel transgenic mouse for gene-targeting within cells that express corticotropin-releasing factor
Q55058368A possible change process of inflammatory cytokines in the prolonged chronic stress and its ultimate implications for health.
Q34311076A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle
Q37080576Addiction and arousal: the hypocretin connection.
Q52049859Alpha-helical CRF blocks differential influence of corticotropin releasing factor (CRF) on appetitive and aversive memory retrieval in rats.
Q36789604Alpha-melanocyte-stimulating hormone attenuates behavioral effects of corticotropin-releasing factor in isolated guinea pig pups
Q35658052Altered anxiety and weight gain in corticotropin-releasing hormone-binding protein-deficient mice
Q36708003Altered emotional and locomotor responses in mice deficient in the transcription factor CREM
Q36309244Amylin blunts hyperphagia and reduces weight and fat gain during recovery in socially stressed rats.
Q85370900Antiglucocorticoids as Treatments for Depression : Rationale for Use and Therapeutic Potential
Q38695316Arginine vasopressin (AVP): a review of its historical perspectives, current research and multifunctional role in the hypothalamo-hypophysial system.
Q33837383Association analysis of the glucocorticoid receptor gene (NR3C1) haplotypes (ER22/23EK, N363S, BclI) with mood and anxiety disorders in patients with asthma
Q35925007Associations between Single-Nucleotide Polymorphisms in Corticotropin-Releasing Hormone-Related Genes and Irritable Bowel Syndrome
Q43714569Bacterial lipopolysaccharide-induced coordinate downregulation of arginine vasopressin receptor V3 and corticotropin-releasing factor receptor 1 messenger ribonucleic acids in the anterior pituitary of endotoxemic steers
Q36600274Behavioral effects of peripheral corticotropin-releasing factor during maternal separation may be mediated by proinflammatory activity
Q42667921Behavioral effects of urotensin-II centrally administered in mice
Q37111899Biological basis of suicide and suicidal behavior
Q51967120Blockade of corticoliberin receptors prevents the development of post-stress psychopathology in rats with an active strategy of adaptive behavior.
Q30494303CRF receptor 1 regulates anxiety behavior via sensitization of 5-HT2 receptor signaling
Q42618279CRF₂ mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats.
Q48710657CRH-R1 and CRH-R2 differentially modulate dendritic outgrowth of hippocampal neurons
Q30514236Central CRF system perturbation in an Alzheimer's disease knockin mouse model.
Q42009557Central adrenal insufficiency and diabetes insipidus misdiagnosed as severe depression
Q33624771Chemical modification of class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies
Q36381383Childhood adversity increases vulnerability for behavioral symptoms and immune dysregulation in women with breast cancer
Q35766585Childhood maltreatment and adult psychopathology: pathways to hypothalamic-pituitary-adrenal axis dysfunction
Q26851378Childhood stressful events, HPA axis and anxiety disorders
Q52712187Chlorpyrifos induced region specific vulnerability in rat CNS and modulation by age and cold stress: an interactive study.
Q42482798Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems.
Q30430100Chronic anabolic androgenic steroid exposure alters corticotropin releasing factor expression and anxiety-like behaviors in the female mouse
Q36211439Class II G protein-coupled receptors and their ligands in neuronal function and protection
Q34740438Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.
Q42146632Co-localization of corticotropin-releasing factor and vesicular glutamate transporters within axon terminals of the rat dorsal raphe nucleus
Q36161776Cognitive disruptions in stress-related psychiatric disorders: A role for corticotropin releasing factor (CRF).
Q36073352Cold stress offered modulation on chlorpyrifos toxicity in aging rat central nervous system
Q48263316Colorectal distention induces acute and delayed visceral hypersensitivity: role of peripheral corticotropin-releasing factor and interleukin-1 in rats.
Q71687283Colorimetric assay for rapid screening of corticotropin releasing factor receptor ligands
Q36499178Comparing biobehavioral profiles across two social stress paradigms in children with and without autism spectrum disorders
Q28577858Comparison of CRF-immunoreactive neurons distribution in mouse and rat brains and selective induction of Fos in rat hypothalamic CRF neurons by abdominal surgery
Q36596573Convergent regulation of locus coeruleus activity as an adaptive response to stress
Q46506794Corticotropin Releasing Factor in the Bed Nucleus of the Stria Terminalis in Socially Defeated and Non-stressed Mice with a History of Chronic Alcohol Intake
Q44386029Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety
Q73703050Corticotropin releasing hormone and related peptides can act as bioregulatory factors in human keratinocytes
Q87910759Corticotropin-Releasing Hormone Binding Protein: Stress, Psychopathology, and Antidepressant Treatment Response
Q30451638Corticotropin-releasing factor acting at the locus coeruleus disrupts thalamic and cortical sensory-evoked responses
Q44911149Corticotropin-releasing factor and acute stress prolongs serotonergic regulation of GABA transmission in prefrontal cortical pyramidal neurons.
Q48686354Corticotropin-releasing factor and glucocorticoid receptor (GR) gene expression in the paraventricular nucleus of immune-challenged transgenic mice expressing type II GR antisense ribonucleic acid
Q34536632Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol
Q37607547Corticotropin-releasing factor in the dorsal raphe nucleus: Linking stress coping and addiction
Q30459620Corticotropin-releasing factor in the norepinephrine nucleus, locus coeruleus, facilitates behavioral flexibility
Q73066542Corticotropin-releasing factor increases in vitro firing rates of serotonergic neurons in the rat dorsal raphe nucleus: evidence for activation of a topographically organized mesolimbocortical serotonergic system
Q38473099Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome.
Q30488089Corticotropin-releasing factor receptors in the dorsal raphe nucleus modulate social behavior in Syrian hamsters.
Q85943965Corticotropin-releasing factor reduces tumor volume, halts further growth, and enhances the effect of chemotherapy in 4T1 mammary carcinoma in mice
Q42679658Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats
Q45128008Corticotropin-releasing hormone directly activates noradrenergic neurons of the locus ceruleus recorded in vitro.
Q39773059Corticotropin-releasing hormone excites adrenocorticotropin-secreting human pituitary adenoma cells by activating a nonselective cation current
Q33947439Corticotropin-releasing hormone inhibits nuclear factor-kappaB pathway in human HaCaT keratinocytes.
Q37082749Corticotropin-releasing hormone receptor expression and functional signaling in murine gonadotrope-like cells
Q39258211Corticotropin-releasing hormone-binding protein and stress: from invertebrates to humans
Q37087511Cortisol and ACTH responses to the Dex/CRH test: influence of temperament
Q47903886Crossroads of corticotropin releasing hormone, corticosteroids and monoamines. About a biological interface between stress and depression
Q37438547Current and novel therapeutic options for irritable bowel syndrome management
Q24633065Cytokines sing the blues: inflammation and the pathogenesis of depression
Q37517285Depression and antidepressants: molecular and cellular aspects.
Q36764298Depression and immunity: inflammation and depressive symptoms in multiple sclerosis
Q49139291Diurnal variation of corticotropin-releasing factor binding sites in the rat brain and pituitary
Q37231289Do corticotropin releasing factor-1 receptors influence colonic transit and bowel function in women with irritable bowel syndrome?
Q35001759Down-regulation of hypothalamic corticotropin-releasing hormone messenger ribonucleic acid (mRNA) precedes early-life experience-induced changes in hippocampal glucocorticoid receptor mRNA.
Q34489314Effect of Triphala on oxidative stress and on cell-mediated immune response against noise stress in rats
Q35596611Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome
Q71227095Effects of ACTH and ACTH 4-10 on aversive memory retrieval in rats
Q30450034Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety
Q33643281Effects of galanin on monoaminergic systems and HPA axis: Potential mechanisms underlying the effects of galanin on addiction- and stress-related behaviors
Q36228218Effects of psychologic stress on fetal development and pregnancy outcome
Q39085570Efficient cationic lipid-mediated delivery of antisense oligonucleotides into eukaryotic cells: down-regulation of the corticotropin-releasing factor receptor
Q30472177Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder
Q37710423Emerging role of alternative splicing of CRF1 receptor in CRF signaling.
Q30394985Endogenous Opioids: The Downside of Opposing Stress
Q30408911Endogenous opioids: opposing stress with a cost
Q37109740Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala
Q35827127Exploration of the Hypothalamic-Pituitary-Adrenal Axis to Improve Animal Welfare by Means of Genetic Selection: Lessons from the South African Merino
Q36460150Exposure to Chronic Mild Stress Differentially Alters Corticotropin-Releasing Hormone and Arginine Vasopressin mRNA Expression in the Stress-Responsive Neurocircuitry of Male and Female Rats Prenatally Exposed to Alcohol
Q48599930Extrahypothalamic corticoliberin receptors regulate the reinforcing effects of self-stimulation.
Q36965806Footshock-induced urinary bladder hypersensitivity: role of spinal corticotropin-releasing factor receptors
Q37321242Functional CRH variation increases stress-induced alcohol consumption in primates
Q28241963GABAA receptor-acting neurosteroids: a role in the development and regulation of the stress response
Q36236640Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner
Q38991472HPA Axis Interactions with Behavioral Systems
Q41501245Human endometrium as a neuroendocrine tissue: expression, regulation and biological roles of endometrial corticotropin-releasing hormone (CRH) and opioid peptides
Q28483614Hypothalamic orexin--a neurons are involved in the response of the brain stress system to morphine withdrawal
Q44293726Hypothalamus-pituitary-adrenal axis in central diabetes insipidus: ACTH and cortisol responsiveness to CRH administration
Q35351250Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome
Q35790395Implication of the hypothalamic-pituitary-adrenal axis in the physiopathology of depression
Q34491885Induction and Expression of Fear Sensitization Caused by Acute Traumatic Stress
Q36439066Inhibition of neuronal nitric oxide reduces anxiety-like responses to pair housing
Q81152624Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response
Q72190599Intra- and extracerebral blood flow changes and flushing after intravenous injection of human corticotropin-releasing hormone
Q36514156Irritable bowel syndrome: recent and novel therapeutic approaches
Q64087792Is the HPA Axis as Target for Depression Outdated, or Is There a New Hope?
Q60719548Localization of the corticotropin-releasing hormone receptor gene on mouse Chromosome 11
Q27307634Long-lasting consequences of neonatal maternal separation on social behaviors in ovariectomized female mice
Q40650533Long-term intracerebroventricular infusion of corticotropin-releasing hormone alters neuroendocrine, neurochemical, autonomic, behavioral, and cytokine responses to a systemic inflammatory challenge.
Q33816520Mammary gene expression profiles during an intramammary challenge reveal potential mechanisms linking negative energy balance with impaired immune response
Q36060471Mapping of the ligand-selective domain of the Xenopus laevis corticotropin-releasing factor receptor 1: implications for the ligand-binding site
Q36070060Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat.
Q35430692Melatonin Attenuates Noise Stress-induced Gastrointestinal Motility Disorder and Gastric Stress Ulcer: Role of Gastrointestinal Hormones and Oxidative Stress in Rats
Q47207303Microbiota Modulate Anxiety-Like Behavior and Endocrine Abnormalities in Hypothalamic-Pituitary-Adrenal Axis
Q28478509Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish
Q47774058Modification of the behavioral effects of corticoliberin by early post-natal administration of corticosteroid hormones
Q35250463Molecular and cellular sex differences at the intersection of stress and arousal.
Q40918840Molecular biology of the regulation of hypothalamic hormones
Q37343344NEUROBIOLOGICAL ASPECTS OF SUICIDE AND SUICIDE ATTEMPTS IN BIPOLAR DISORDER.
Q34695129NEUROBIOLOGY OF ADULT AND TEENAGE SUICIDE
Q37364474Neonatal treatment of rats with the neuroactive steroid tetrahydrodeoxycorticosterone (THDOC) abolishes the behavioral and neuroendocrine consequences of adverse early life events
Q39017236Neural Underpinnings of Decision Strategy Selection: A Review and a Theoretical Model.
Q37173485Neurobiology of suicidal behavior. An integration of biological and clinical findings
Q41508067Neuroendocrine mechanisms of the formation of adaptive behavior
Q37087117Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer
Q28069771Neuroinflammation at the interface of depression and cardiovascular disease: Evidence from rodent models of social stress
Q34081783Neuropsychiatric adverse effects of interferon-alpha: recognition and management
Q21129366Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress
Q37072730Novel expression of type 1 corticotropin-releasing hormone receptor in multiple endocrine cell types in the murine anterior pituitary
Q34228120On the role of corticotropin-releasing hormone receptors in anxiety and depression
Q43171063On the role of the corticotropin-releasing hormone signalling system in the aetiology of inflammatory skin disorders
Q40832553Overexpressing Corticotropin-Releasing Factor in the Primate Amygdala Increases Anxious Temperament and Alters Its Neural Circuit
Q24567741Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders
Q34726454Personalized medicine in psychiatry: problems and promises
Q47686059Physiological and neurochemical aspects of corticotropin-releasing factor actions in the brain: the role of the locus coeruleus
Q26830683Physiological underpinnings of irritable bowel syndrome: neurohormonal mechanisms
Q35988500Pituitary CRH-binding protein and stress in female mice
Q48519599Prenatal stress enhances stress- and corticotropin-releasing factor-induced stimulation of hippocampal acetylcholine release in adult rats.
Q37114415Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension
Q43653423Psychological stress increases hippocampal mineralocorticoid receptor levels: involvement of corticotropin-releasing hormone.
Q42454582Reduced activity of hypothalamic corticotropin-releasing hormone neurons in transgenic mice with impaired glucocorticoid receptor function.
Q48823444Regulation of a putative neurotransmitter effect of corticotropin-releasing factor: effects of adrenalectomy.
Q40437410Regulation of adrenocorticotropic hormone secretion: lessons from mice deficient in corticotropin-releasing hormone
Q30498987Regulation of corticosteroid receptor gene expression in depression and antidepressant action
Q43578204Regulation of serotonin release in the lateral septum and striatum by corticotropin-releasing factor.
Q47903674Relationships between trait and respiratory parameters during quiet breathing in normal subjects
Q42714025Relaxing actions of corticotropin-releasing factor on rat resistance arteries.
Q35020584Residues remote from the binding pocket control the antagonist selectivity towards the corticotropin-releasing factor receptor-1.
Q34294075Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system
Q47607724Sex differences in circuits activated by corticotropin releasing factor in rats
Q64276138Sex differences in corticotropin releasing factor regulation of medial septum-mediated memory formation
Q28583583Sex differences in corticotropin-releasing factor receptor signaling and trafficking: potential role in female vulnerability to stress-related psychopathology
Q36044962Sex differences in molecular and cellular substrates of stress.
Q36923878Sex differences in the locus coeruleus-norepinephrine system and its regulation by stress
Q37071838Sex- and corticotropin-releasing factor receptor 2- dependent actions of urocortin 1 during inflammation
Q37618519Sex-biased cellular signaling: molecular basis for sex differences in neuropsychiatric diseases
Q36627753Sexual dimorphism of stress response and immune/ inflammatory reaction: the corticotropin releasing hormone perspective
Q37328849Soluble corticotropin-releasing hormone receptor 2alpha splice variant is efficiently translated but not trafficked for secretion
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