Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

scientific article published on 17 April 2009

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.ADDR.2009.03.009
P932PMC publication ID3683962
P698PubMed publication ID19376175
P5875ResearchGate publication ID222990777

P2093author name stringJennifer B Hall
Marina A Dobrovolskaia
Scott E McNeil
Parag Aggarwal
Christopher B McLeland
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P433issue6
P407language of work or nameEnglishQ1860
P921main subjectnanoparticleQ61231
P304page(s)428-437
P577publication date2009-04-17
P1433published inAdvanced Drug Delivery ReviewsQ2825362
P1476titleNanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
P478volume61

Reverse relations

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Q31124745Microwave-assisted green synthesis of superparamagnetic nanoparticles using fruit peel extracts: surface engineering, T 2 relaxometry, and photodynamic treatment potential
Q40562574Modulation of Protein Fouling and Interfacial Properties at Carbon Surfaces via Immobilization of Glycans Using Aryldiazonium Chemistry.
Q35814950Modulation of Silica Nanoparticle Uptake into Human Osteoblast Cells by Variation of the Ratio of Amino and Sulfonate Surface Groups: Effects of Serum.
Q89510832Molecular Mechanisms of the Interactions of N-(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins
Q61798103Molecular interaction of fibrinogen with zeolite nanoparticles
Q50926807Monodispersity of magnetic immuno-nanoprobes enhances the detection sensitivity of low abundance biomarkers in one drop of serum.
Q51736820Morphology-Variable Aggregates Prepared from Cholesterol-Containing Amphiphilic Glycopolymers: Their Protein Recognition/Adsorption and Drug Delivery Applications.
Q59794223Multifunctional Platform Based on Electroactive Polymers and Silica Nanoparticles for Tissue Engineering Applications
Q58812768Multifunctional Silica Nanoparticles for Covalent Immobilization of Highly Sensitive Proteins
Q40765081Multiple Administrations of Viral Nanoparticles Alter in Vivo Behavior-Insights from Intravital Microscopy.
Q45789061Multiwavelength transmission spectroscopy revisited for the characterization of the protein and polystyrene nanoparticle interactions
Q39561959Nano meets biology: structure and function at the nanoparticle interface
Q37967661Nanobiotechnology for the capture and manipulation of circulating tumor cells
Q27027067Nanocarriers for vascular delivery of antioxidants
Q59204660Nanocarriers with dual pH-sensitivity for enhanced tumor cell uptake and rapid intracellular drug release
Q35381211Nanodetoxification: emerging role of nanomaterials in drug intoxication treatment
Q64089402Nanomaterial Exposure Induced Neutrophil Extracellular Traps: A New Target in Inflammation and Innate Immunity
Q37857064Nanomaterials: applications in cancer imaging and therapy.
Q38383478Nanomedicine for gene therapy.
Q28395287Nanoparticle Uptake: The Phagocyte Problem
Q58585993Nanoparticle probes for quantifying supramolecular determinants of biosurface affinity
Q45719861Nanoparticle stability in biologically relevant media: influence of polymer architecture.
Q38123458Nanoparticle systems as tools to improve drug delivery and therapeutic efficacy.
Q38167942Nanoparticle vaccines
Q50226473Nanoparticle-based strategies for cancer immunotherapy and immunodiagnostics.
Q28384480Nanoparticles and direct immunosuppression
Q37612053Nanoparticles and the blood coagulation system. Part II: safety concerns
Q33634320Nanoparticles and the immune system
Q57377197Nanoparticles combined with growth factors: recent progress and applications
Q34010233Nanoparticles for imaging, sensing, and therapeutic intervention
Q26825418Nanoparticulate adjuvants and delivery systems for allergen immunotherapy
Q38218145Nanoparticulate carrier system: a novel treatment approach for hyperlipidemia
Q47818560Nanotechnology and primary hemostasis: Differential effects of nanoparticles on platelet responses.
Q35943647Nanotechnology and the treatment of HIV infection.
Q39631113Nanotoxicity: how the body develops a way to reduce the toxicity of carbon nanotubes
Q57345630Nanotoxicology: Contemporary Issues and Future Directions
Q37624470Negatively charged metal oxide nanoparticles interact with the 20S proteasome and differentially modulate its biologic functional effects
Q64819927Neurotheranostics as personalized medicines
Q47447868Neutrophil-Particle Interactions in Blood Circulation Drive Particle Clearance and Alter Neutrophil Responses in Acute Inflammation
Q38183853New views and insights into intracellular trafficking of drug-delivery systems by fluorescence fluctuation spectroscopy.
Q38364473No king without a crown--impact of the nanomaterial-protein corona on nanobiomedicine
Q52431943Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities.
Q58097605Novel Delivery of Mitoxantrone with Hydrophobically Modified Pullulan Nanoparticles to Inhibit Bladder Cancer Cell and the Effect of Nano-drug Size on Inhibition Efficiency
Q26991771Novel formulations for antimicrobial peptides
Q49575081Occupational exposure to ultrafine particles in police officers: no evidence for adverse respiratory effects.
Q91693455Overcoming Hurdles in Nanoparticle Clinical Translation: The Influence of Experimental Design and Surface Modification
Q64264041Overview of Carbon Nanotubes for Biomedical Applications
Q90579730Overview of the blood compatibility of nanomedicines: A trend analysis of in vitro and in vivo studies
Q37693763Overview of the main methods used to combine proteins with nanosystems: absorption, bioconjugation, and encapsulation.
Q36299217PEG-b-AGE Polymer Coated Magnetic Nanoparticle Probes with Facile Functionalization and Anti-fouling Properties for Reducing Non-specific Uptake and Improving Biomarker Targeting.
Q34149180PEGylated PRINT nanoparticles: the impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics
Q55449441PEGylation of polypropylenimine dendrimers: effects on cytotoxicity, DNA condensation, gene delivery and expression in cancer cells.
Q38401187Parameters and characteristics governing cellular internalization and trans-barrier trafficking of nanostructures
Q47794249Particle Targeting in Complex Biological Media
Q38807176Past, Present, and Future Drug Delivery Systems for Antiretrovirals
Q60184483Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications
Q38881377Personalized disease-specific protein corona influences the therapeutic impact of graphene oxide
Q38947400Phosphatidylcholine-coated iron oxide nanomicelles for in vivo prolonged circulation time with an antibiofouling protein corona
Q91912625Physalis Mottle Virus-like Nanoparticles for Targeted Cancer Imaging
Q58547073Physicochemical Characterization of FRET-Labelled Chitosan Nanocapsules and Model Degradation Studies
Q35190894Physicochemical characterization of nanoparticles and their behavior in the biological environment
Q28392831Physicochemical properties of nanomaterials: implication in associated toxic manifestations
Q39005101Physiologically Based Pharmacokinetic (PBPK) Modeling of Pharmaceutical Nanoparticles
Q47570893Plasma protein adsorption and biological identity of systemically administered nanoparticles
Q27026623Plasma proteins interaction with curcumin nanoparticles: implications in cancer therapeutics
Q39027154Poly(methyl vinyl ether-alt-maleic acid)-functionalized porous silicon nanoparticles for enhanced stability and cellular internalization
Q51186932Polyelectrolyte Oil-Core Nanocarriers for Localized and Sustained Delivery of Daunorubicin to Colon Carcinoma MC38 Cells: The Case of Polysaccharide Multilayer Film in Relation to PEG-ylated Shell.
Q38902155Potential of biofluid components to modify silver nanoparticle toxicity
Q57947038Pre-coating with protein fractions inhibits nano-carrier aggregation in human blood plasma
Q44549040Probing lipid coating dynamics of quantum dot core micelles via Förster resonance energy transfer
Q41949821Probing of the assembly structure and dynamics within nanoparticles during interaction with blood proteins.
Q51084208Probing the binding affinity of plasma proteins adsorbed on Au nanoparticles.
Q26740580Progress and perspectives on targeting nanoparticles for brain drug delivery.
Q30714285Progress on the diagnosis and evaluation of brain tumors.
Q92989097Protein Adsorption: A Feasible Method for Nanoparticle Functionalization?
Q38674654Protein Corona: Impact of Lymph Versus Blood in a Complex In Vitro Environment.
Q57947040Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers
Q37651354Protein bio-corona: critical issue in immune nanotoxicology
Q26853351Protein corona - from molecular adsorption to physiological complexity
Q91866982Protein corona formed on silver nanoparticles in blood plasma is highly selective and resistant to physicochemical changes of the solution
Q46454818Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity
Q46029993Protein corona on magnetite nanoparticles and internalization of nanoparticle-protein complexes into healthy and cancer cells.
Q39274203Protein corona: a new approach for nanomedicine design
Q97644950Protein electrostatics: From computational and structural analysis to discovery of functional fingerprints and biotechnological design
Q36142197Protein-based photothermal theranostics for imaging-guided cancer therapy
Q37850776QSAR modeling of nanomaterials
Q28392542Quantitative analysis of nanoparticle transport through in vitro blood-brain barrier models
Q35214069Quantitative comparison of tumor delivery for multiple targeted nanoparticles simultaneously by multiplex ICP-MS
Q51429705RNA-binding proteins are a major target of silica nanoparticles in cell extracts.
Q39093144Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology
Q35300570Real time monitoring of biomaterial-mediated inflammatory responses via macrophage-targeting NIR nanoprobes
Q91669702Recent Advances in the Use of Focused Ultrasound for Magnetic Resonance Image-Guided Therapeutic Nanoparticle Delivery to the Central Nervous System
Q92798768Recent expansions of novel strategies towards the drug targeting into the brain
Q36889993Recovery of Drug Delivery Nanoparticles from Human Plasma Using an Electrokinetic Platform Technology
Q50282486Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance.
Q59134586Regulatory Aspects of Oncologicals: Nanosystems Main Challenges
Q33713687Relationships between Poly(ethylene glycol) Modifications on RNA-Spherical Nucleic Acid Conjugates and Cellular Uptake and Circulation Time
Q57161039Renal Clearable Luminescent Gold Nanoparticles: From Bench to Clinics
Q36058748Repeated injection of PEGylated solid lipid nanoparticles induces accelerated blood clearance in mice and beagles
Q56976666Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles
Q89913837Reversible Control of Protein Corona Formation on Gold Nanoparticles Using Host-Guest Interactions
Q38821105Revisiting the nanoformulation design approach for effective delivery of topotecan in its stable form: an appraisal of its in vitro Behavior and tumor amelioration potential.
Q39447640Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population
Q53230602Self-Assembled Fluorescent Nanoparticles from π-Conjugated Small Molecules: En Route to Biological Applications.
Q47861975Sensing of Alzheimer's Disease and Multiple Sclerosis Using Nano-Bio Interfaces.
Q45787949Serum enhanced cytokine responses of macrophages to silica and iron oxide particles and nanomaterials: a comparison of serum to lung lining fluid and albumin dispersions
Q36468223Serum protein adsorption and excretion pathways of metal nanoparticles
Q55450179Shape-, size- and structure-controlled synthesis and biocompatibility of iron oxide nanoparticles for magnetic theranostics.
Q35527009Side-by-Side Comparison of Commonly Used Biomolecules That Differ in Size and Affinity on Tumor Uptake and Internalization
Q35393931Silica nanoconstruct cellular toleration threshold in vitro
Q35703091Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration.
Q38807256Solid lipid nanoparticles as a drug delivery system for the treatment of neurodegenerative diseases.
Q35039920Spherical nucleic acid nanoparticle conjugates enhance G-quadruplex formation and increase serum protein interactions
Q47324311Spontaneous protein desorption from self-assembled monolayer (SAM)-coated gold nanoparticles.
Q46048775Stealth Biocompatible Si-Based Nanoparticles for Biomedical Applications.
Q27027780Stimulating antitumor immunity with nanoparticles
Q30836736Strategies for interfacing inorganic nanocrystals with biological systems based on polymer-coating
Q38017713Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers
Q38567353Stromal barriers and strategies for the delivery of nanomedicine to desmoplastic tumors
Q35055270Structural determinants for protein adsorption/non-adsorption to silica surface
Q57795199Structure-Stability-Function Mechanistic Links in the Anti-Measles Virus Action of Tocopherol-Derivatized Peptide Nanoparticles
Q97523873Sulfoxide-Containing Polymer-Coated Nanoparticles Demonstrate Minimal Protein Fouling and Improved Blood Circulation
Q58493156Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro
Q39298856Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor.
Q37334228Surface charges and shell crosslinks each play significant roles in mediating degradation, biofouling, cytotoxicity and immunotoxicity for polyphosphoester-based nanoparticles
Q42268182Surface hydrolysis-mediated PEGylation of poly(N-isopropyl acrylamide) based nanogels
Q33850450Surface-Modification of Carbonate Apatite Nanoparticles Enhances Delivery and Cytotoxicity of Gemcitabine and Anastrozole in Breast Cancer Cells
Q42284052Synthesis and Characterization of PMBN as A Biocompatible Nanopolymer for Bio-Applications
Q39393477Tailoring of physicochemical properties of nanocarriers for effective anti-cancer applications
Q36934007Targeted polymeric therapeutic nanoparticles: design, development and clinical translation
Q38703125Taxane-Grafted Metal-Oxide Nanoparticles as a New Theranostic Tool against Cancer: The Promising Example of Docetaxel-Functionalized Titanate Nanotubes on Prostate Tumors.
Q90223130Temperature-Responsive Hydrophobic Silica Nanoparticle Ultrasound Contrast Agents Directed by Phospholipid Phase Behavior
Q53127398Tetanus toxoid-loaded cationic non-aggregated nanostructured lipid particles triggered strong humoral and cellular immune responses.
Q51004786The Impact of Protein Corona Formation on the Macrophage Cellular Uptake and Biodistribution of Spherical Nucleic Acids.
Q50220267The Nature of a Hard Protein Corona Forming on Quantum Dots Exposed to Human Blood Serum.
Q41843707The Next Generation Non-competitive Active Polyester Nanosystems for Transferrin Receptor-mediated Peroral Transport Utilizing Gambogic Acid as a Ligand
Q47391647The Protein Corona around Nanoparticles Facilitates Stem Cell Labeling for Clinical MR Imaging.
Q58803479The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery
Q91973095The Role of Nanomaterials in the Treatment of Diseases and Their Effects on the Immune System
Q58493134The Role of the Protein Corona in Fiber Structure-Activity Relationships
Q34447943The adsorption of biomolecules to multi-walled carbon nanotubes is influenced by both pulmonary surfactant lipids and surface chemistry
Q38996952The biocompatibility evaluation of mPEG-PLGA-PLL copolymer and different LA/GA ratio effects for biocompatibility
Q27013605The biomechanisms of metal and metal-oxide nanoparticles' interactions with cells
Q28384138The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity
Q28386401The effect of blood protein adsorption on cellular uptake of anatase TiO2 nanoparticles
Q38168566The effect of nanoparticle properties, detection method, delivery route and animal model on poly(lactic-co-glycolic) acid nanoparticles biodistribution in mice and rats
Q38722460The effect of polyanhydride chemistry in particle-based cancer vaccines on the magnitude of the anti-tumor immune response
Q42913725The effect of zinc oxide nanoparticles on the structure of the periplasmic domain of the Vibrio cholerae ToxR protein.
Q35223423The fate of calcium carbonate nanoparticles administered by oral route: absorption and their interaction with biological matrices
Q28085280The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery
Q38176391The interaction of nanoparticles with plasma proteins and the consequent influence on nanoparticles behavior
Q43078999The interplay of monolayer structure and serum protein interactions on the cellular uptake of gold nanoparticles.
Q28083583The janus facet of nanomaterials
Q54645900The nanotoxicology revolution.
Q40106774The role of nanotechnology in the treatment of viral infections.
Q38236719The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy.
Q36807868The role of surface functionality in determining nanoparticle cytotoxicity
Q50046147The surface chemistry determines the spatio-temporal interaction dynamics of quantum dots in atherosclerotic lesions.
Q38886457The surfactant dipalmitoylphophatidylcholine modifies acute responses in alveolar carcinoma cells in response to low-dose silver nanoparticle exposure
Q38555085Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy
Q39665792Thermally Triggered Cellular Uptake of Quantum Dots Immobilized with Poly(N-isopropylacrylamide) and Cell Penetrating Peptide
Q96809436Thermodynamic parameters at bio-nano interface and nanomaterial toxicity: A case study on BSA interaction with ZnO, SiO2 and TiO2
Q38655546Titanium dioxide nanoparticles preferentially bind in subdomains IB, IIA of HSA and minor groove of DNA.
Q28071613Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms
Q28383168Toxicity of nanomaterials
Q38255894Toxicity of single-walled carbon nanotubes
Q38009230Toxico-/biokinetics of nanomaterials
Q38968620Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity.
Q53461387Tumor-acidity activated surface charge-conversion of polymeric nanocarriers for enhanced cell adhesion and targeted drug release.
Q33816969Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers.
Q57348100Tuning the composition of biocompatible Gd nanohydrogels to achieve hypersensitive dual T1/T2 MRI contrast agents
Q38954326Two-Dimensional Nanomaterials for Biomedical Applications: Emerging Trends and Future Prospects
Q36010379Ultrapure laser-synthesized Si-based nanomaterials for biomedical applications: in vivo assessment of safety and biodistribution.
Q93273323Unbiased Identification of the Liposome Protein Corona using Photoaffinity-based Chemoproteomics
Q91801319Understanding the Influence of a Bifunctional Polyethylene Glycol Derivative in Protein Corona Formation around Iron Oxide Nanoparticles
Q36739647Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future
Q55336529Use of Submicron Vaterite Particles Serves as an Effective Delivery Vehicle to the Respiratory Portion of the Lung.
Q36844202Using the Power of Organic Synthesis for Engineering the Interactions of Nanoparticles with Biological Systems
Q38834911Utilizing the protein corona around silica nanoparticles for dual drug loading and release
Q41868722Validity range of centrifuges for the regulation of nanomaterials: from classification to as-tested coronas
Q51732274Vascular biosafety of commercial hydroxyapatite particles: discrepancy between blood compatibility assays and endothelial cell behavior.
Q38652067Versatility of Pyridoxal Phosphate as a Coating of Iron Oxide Nanoparticles
Q37403163X-ray computed tomography imaging of a tumor with high sensitivity using gold nanoparticles conjugated to a cancer-specific antibody via polyethylene glycol chains on their surface
Q48400402X-ray microscopy and tomography detect the accumulation of bare and PEG-coated gold nanoparticles in normal and tumor mouse tissues.
Q34074782Zwitteration: coating surfaces with zwitterionic functionality to reduce nonspecific adsorption
Q36382827Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.
Q54358989[Use of nanoparticles in ophthalomology].
Q58732419biological fate of poly(vinylalcohol) microbubbles in mice
Q37449500pH-Sensitive Pt Nanocluster Assembly Overcomes Cisplatin Resistance and Heterogeneous Stemness of Hepatocellular Carcinoma
Q53091050pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin.

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