Biology of dendritic cells in aging

scientific article published on 09 September 2007

Biology of dendritic cells in aging is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1007/S10875-007-9127-6
P698PubMed publication ID17828583

P2093author name stringSudhanshu Agrawal
Sudhir Gupta
Anshu Agrawal
Jia Tay
P2860cites workThe induction of tolerance by dendritic cells that have captured apoptotic cellsQ24671078
Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial productsQ24678867
APC-derived cytokines and T cell polarization in autoimmune inflammationQ24679426
Dendritic cells and the control of immunityQ27860918
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathwayQ28588309
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organsQ28594485
Immunobiology of dendritic cellsQ29547465
IL-23 drives a pathogenic T cell population that induces autoimmune inflammationQ29547525
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brainQ29614225
A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophagesQ29616748
Tolerogenic dendritic cellsQ29618755
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivoQ30080006
Deterioration of the Langerhans cell network of the human gingival epithelium with agingQ33254490
Age-related changes in lymphocyte development and functionQ34293466
CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorlyQ34390579
Chronological ageing and photoageing of dendritic cellsQ34429513
Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cellsQ34578511
Oligoclonal expansions of antigen-specific CD8+ T cells in aged miceQ35120006
Autoimmunity and geriatrics: clinical significance of autoimmune manifestations in the elderlyQ35135284
PI3K and negative regulation of TLR signaling.Q35177702
Immunosenescence, autoimmunity, and rheumatoid arthritisQ35198258
Ineffective humoral immunity in the elderlyQ35586492
Age-dependent changes in thymic macrophages and dendritic cells.Q35591803
Chemokine mediated control of dendritic cell migration and function.Q35682768
Characterization of naïve, memory and effector CD8+ T cells: effect of age.Q35721426
The immune system in the elderly: activation-induced and damage-induced apoptosisQ35838671
Inflamm-aging: autoimmunity, and the immune-risk phenotypeQ35852899
Mucosal immunity and tolerance in the elderlyQ35962900
Intrinsic versus environmental influences on T-cell responses in agingQ36121052
Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situQ36352646
Antigen-independent changes in naive CD4 T cells with agingQ36367675
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cellsQ36375909
Dendritic cells in human agingQ36689442
Development of dendritic-cell lineagesQ36854617
Innate signaling and regulation of Dendritic cell immunityQ36880625
Histologic changes in skin associated with agingQ37980518
Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient miceQ39996558
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cellsQ40726959
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
The aging immune system: primer and prospectusQ41003059
Phosphatidylinositol 3-kinase regulation of fluid phase endocytosisQ41327182
The aging immune system: primary and secondary alterations of immune reactivity in the elderlyQ41604636
T cells and agingQ41676488
Effect of chronologic aging and ultraviolet irradiation on Langerhans cells in human epidermis.Q42468553
TNF-alpha-induced apoptosis in human naïve and memory CD8+ T cells in aged humansQ43505439
Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunityQ43800695
Influence of ageing on Langerhans cell migration in mice: identification of a putative deficiency of epidermal interleukin-1betaQ43977303
Polymorphism of age-related changes in interleukin (IL) production: differential changes of T helper subpopulations, synthesizing IL 2, IL 3 and IL 4.Q44286299
Impairment of dendritic cells and adaptive immunity by anthrax lethal toxinQ44389292
Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharideQ44504190
Age-related inflammatory cytokines and diseaseQ44662101
Differential sensitivity of naïve and memory subsets of human CD8+ T cells to TNF-alpha-induced apoptosis.Q45977925
Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathwayQ46978957
A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cellsQ47810460
Inflammatory processes in the aging mouse brain: participation of dendritic cells and T-cells.Q48426463
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expressionQ52061718
Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos.Q52956682
Effects of age on antibody affinity maturationQ58045505
Peripheral blood dendritic cells and monocytes are differently regulated in the elderlyQ59116823
Cutting edge: impaired Toll-like receptor expression and function in agingQ64127747
Effect of aging on epidermal dendritic cell populations in C57BL/6J miceQ68700573
Epidermal Langerhans cell density and contact sensitivity in young and aged BALB/c miceQ69154814
Cell-mediated immunity in aged mice: an underlying lesion in IL 2 synthesisQ70566334
Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individualsQ71537276
Abnormalities of B cells and dendritic cells in SAMP1 miceQ71696213
[Age-dependent distribution of Langerhans cells within human conjunctival epithelium]Q72160589
The Effect of Aging and Chronic Sun Exposure on Human Langerhans Cell PopulationsQ72725503
Quantitative analysis of CD1a (T6) positive Langerhans cells in human tonsil epitheliumQ73297964
Unimpaired dendritic cells can be derived from monocytes in old age and can mobilize residual function in senescent T cellsQ73480267
Surface markers and transendothelial migration of dendritic cells from elderly subjectsQ73682314
Phenotype, antigen-presenting capacity, and migration of antigen-presenting cells in young and old ageQ74734253
The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- and in vivo-derived dendritic cellsQ77320320
Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageingQ77631195
Circulating, interferon-producing plasmacytoid dendritic cells decline during human ageingQ78458996
Effect of aging on bone marrow-derived murine CD11c+CD4-CD8alpha- dendritic cell functionQ79319562
Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with agingQ79385275
Aging affect the anti-tumor potential of dendritic cell vaccination, but it can be overcome by co-stimulation with anti-OX40 or anti-4-1BBQ81484552
P433issue1
P921main subjectdendritic cellQ506253
P304page(s)14-20
P577publication date2007-09-09
P1433published inJournal of Clinical ImmunologyQ6294961
P1476titleBiology of dendritic cells in aging
P478volume28

Reverse relations

cites work (P2860)
Q37731383Adaptive and Innate Immune Responses in Autism: Rationale for Therapeutic Use of Intravenous Immunoglobulin
Q35578642Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice
Q28573902Aging affects AO rat splenic conventional dendritic cell subset composition, cytokine synthesis and T-helper polarizing capacity
Q37525662Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors.
Q92540693Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity
Q44949031Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood
Q34731582Aging of the Innate Immune System: An Update
Q36128689An In Vitro Approach to Study Effects of Prebiotics and Probiotics on the Faecal Microbiota and Selected Immune Parameters Relevant to the Elderly
Q57151334Blood immune cell biomarkers in lung cancer
Q42217223Cardiovascular exercise intervention improves the primary antibody response to keyhole limpet hemocyanin (KLH) in previously sedentary older adults.
Q33903477Chemokine expression patterns in the systemic and genital tract compartments are associated with HIV-1 infection in women from Benin
Q38815953Considerations for successful cancer immunotherapy in aged hosts
Q37952779Donor age-specific injury and immune responses
Q34314270Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication.
Q58575877Effects of Acute and Chronic Exercise on Immunological Parameters in the Elderly Aged: Can Physical Activity Counteract the Effects of Aging?
Q55154202Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.
Q43748921Enumeration of human peripheral blood dendritic cells throughout the life
Q37823854Expanding the universe of cytokines and pattern recognition receptors: galectins and glycans in innate immunity
Q33872432Immunosenescence and immune response in organ transplantation.
Q26861735Immunosenescence and organ transplantation
Q37301037Immunosenescence: what does it mean to health outcomes in older adults?
Q38063349Impact of immunosenescence on transplant outcome
Q35803356Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin
Q43248890Impaired dendritic cell function in aging leads to defective antitumor immunity
Q36929586Innate immunity and aging
Q33755484Leukocyte function in the aging immune system
Q36031500Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction
Q37350766Mechanisms of murine dendritic cell antitumor dysfunction in aging
Q48002812Mice with heterozygous deficiency of manganese superoxide dismutase (SOD2) have a skin immune system with features of "inflamm-aging".
Q46492182Morphology of the non-sensory tissue components in rat aging vomeronasal organ
Q59322424O19 - Changes in the balance between myeloid (mDC) and plasmacytoid (pDC) cell numbers in peripheral blood during childhood
Q37605983Ocular surface disease and dacryoadenitis in aging C57BL/6 mice.
Q33939473Plasmacytoid DC from aged mice down-regulate CD8 T cell responses by inhibiting cDC maturation after Encephalitozoon cuniculi infection
Q36274133Preferential enhancement of older human T cell cytokine generation, chemotaxis, proliferation and survival by lenalidomide
Q37364851Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients
Q23916837Susceptibility of the aging lung to environmental injury
Q37357018The ageing immune system: is it ever too old to become young again?
Q37637719The aging immune system and its relationship to the development of chronic obstructive pulmonary disease
Q38712466The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging
Q37761424The impact of varicella zoster virus: chronic pain
Q89820626Transplantation of Marginal Organs: Immunological Aspects and Therapeutic Perspectives in Kidney Transplantation
Q42702859Understanding ageing: biomedical and bioengineering approaches, the immunologic view
Q27022304Vaccination in the elderly