Control of Trx1 redox state modulates protection against methyl methanesulfonate-induced DNA damage via stabilization of p21.

scientific article published on 13 August 2015

Control of Trx1 redox state modulates protection against methyl methanesulfonate-induced DNA damage via stabilization of p21. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JB/MVV080
P932PMC publication ID4882645
P698PubMed publication ID26276860

P2093author name stringHong Zhang
Wei Gao
Jianguo Xu
Li Gu
Hui Min Yang
Xiao Na Wang
Bei Bei Wang
P2860cites workIdentification of redox/repair protein Ref-1 as a potent activator of p53Q24316161
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.Q24533236
Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductaseQ24630110
Functional specialization of Chlamydomonas reinhardtii cytosolic thioredoxin h1 in the response to alkylation-induced DNA damageQ33859467
p38 mitogen-activated protein kinase promotes cell survival in response to DNA damage but is not required for the G(2) DNA damage checkpoint in human cancer cellsQ34045669
Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent mannerQ34135937
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1Q34422019
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1.Q35066218
APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.Q35870045
Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitorsQ35871417
The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cellsQ35889790
Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significanceQ36629722
Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular systemQ36685478
Methylating agents and DNA repair responses: Methylated bases and sources of strand breaksQ36686012
The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cellsQ37062050
UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stabilityQ37080401
Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response.Q37680260
A midlife crisis for the mitochondrial free radical theory of agingQ37688409
Redox control and interplay between p53 isoforms: roles in the regulation of basal p53 levels, cell fate, and senescenceQ37824866
Redox regulation of the proteasome via S-glutathionylation.Q38176369
Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21Cip1/WAF1 pathwaysQ39388968
Suppression of thioredoxin-1 induces premature senescence in normal human fibroblastsQ39751961
Antioxidant activity of diphenyl diselenide prevents the genotoxicity of several mutagens in Chinese hamster V79 cells.Q40132075
Cytoplasmic localization and ubiquitination of p21(Cip1) by reactive oxygen speciesQ40137505
Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen speciesQ40694681
H(2)O(2)-induced AP-1 activation and its effect on p21(WAF1/CIP1)-mediated G2/M arrest in a p53-deficient human lung cancer cellQ40726746
DNA-damaging agents cause inactivation of translational regulators linked to mTOR signallingQ40871212
Overexpression of thioredoxin in Fanconi anemia fibroblasts prevents the cytotoxic and DNA damaging effect of mitomycin C and diepoxybutane.Q41063911
Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiaeQ41337790
The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agentsQ41846051
Lafora disease fibroblasts exemplify the molecular interdependence between thioredoxin 1 and the proteasome in mammalian cells.Q42816584
H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expressionQ42818949
DNA damage induction by two halogenated acetaldehydes, byproducts of water disinfectionQ43147372
DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiaeQ43180435
Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicityQ44131325
Thioredoxin-dependent redox regulation of p53-mediated p21 activationQ44275159
Adiponectin induces apoptosis in hepatocellular carcinoma through differential modulation of thioredoxin proteinsQ46798108
Oxidative stress response results in increased p21WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells.Q46842795
Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survivalQ47739141
The heat-stable cytosolic factor that promotes glucocorticoid receptor binding to DNA is neither thioredoxin nor ribonucleaseQ69452150
Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate readerQ73000450
Apurinic/apyrimidinic endonuclease 1, p53, and thioredoxin are linked in control of aging in C. elegansQ83932457
P4510describes a project that usesImageJQ1659584
P433issue1
P304page(s)101-110
P577publication date2015-08-13
P1433published inJournal of BiochemistryQ6294839
P1476titleControl of Trx1 redox state modulates protection against methyl methanesulfonate-induced DNA damage via stabilization of p21.
P478volume159

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cites work (P2860)
Q38759877Comet assay: an essential tool in toxicological research
Q59330143Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway

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