Mechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver

scientific article published on July 2008

Mechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MRFMMM.2008.06.009
P932PMC publication ID2571982
P698PubMed publication ID18639561
P5875ResearchGate publication ID51413721

P50authorVolodymyr TryndyakQ55446237
P2093author name stringIvan Rusyn
Beverly Montgomery
Igor P Pogribny
Stepan Melnyk
Tetyana V Bagnyukova
Anna Boureiko
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Phenobarbital induces progressive patterns of GC-rich and gene-specific altered DNA methylation in the liver of tumor-prone B6C3F1 miceQ82827752
Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localizationQ34061084
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Hepatocyte-restricted constitutive activation of PPAR alpha induces hepatoproliferation but not hepatocarcinogenesisQ35830218
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinomaQ35945177
Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.Q36202782
The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).Q36328530
Molecular mechanisms of human carcinogenesisQ36355761
Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.Q36586072
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Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant stateQ36950762
PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferatorsQ37002053
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elementsQ39695383
Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation.Q40599799
Quantification of 3'OH DNA breaks by random oligonucleotide-primed synthesis (ROPS) assayQ41223814
Influence of oxygen radical injury on DNA methylation.Q41439646
Large-scale structure of genomic methylation patternsQ42186756
Wy-14,643-induced hypomethylation of the c-myc gene in mouse liverQ43635306
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min miceQ44285111
Progressive alterations in global and GC-rich DNA methylation during tumorigenesisQ44527204
Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferatorsQ44761807
DNA hypomethylation induced by drinking water disinfection by-products in mouse and rat kidneyQ46598686
Global DNA hypomethylation in liver cancer cases and controls: a phase I preclinical biomarker development study.Q46886305
Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice.Q51579160
Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.Q53342403
Single-site methylation within the p53 promoter region reduces gene expression in a reporter gene construct: possible in vivo relevance during tumorigenesis.Q53413487
Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.Q53519250
Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.Q53536112
Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency.Q54451004
Di-(2-ethylhexyl)phthalate: An industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rats and miceQ67455009
Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: alterations with plasma homocysteine and pyridoxal 5'-phosphate concentrationsQ73406154
Hypomethylation of the rat glutathione S-transferase pi (GSTP) promoter region isolated from methyl-deficient livers and GSTP-positive liver neoplasmsQ77322498
P4510describes a project that usesImageQuantQ112270642
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)17-23
P577publication date2008-07-01
P1433published inMutation ResearchQ6943732
P1476titleMechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver
P478volume644

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