Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids

scientific article published on 8 November 2007

Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/BI7011993
P932PMC publication ID2576749
P698PubMed publication ID17988103

P2093author name stringRima McLeod
Mary Roth
Craig W Roberts
Eric Maréchal
Giorgis Isaac
Ruth Welti
Sarah Wernimont
Cyrille Botté
Alexis Sparks
Ernie Mui
Michael Kirisits
P2860cites workStructures of Toxoplasma gondii tachyzoites, bradyzoites, and sporozoites and biology and development of tissue cysts.Q24520491
Studies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agentsQ27643926
Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylaseQ28343700
The apicoplast: a new member of the plastid familyQ29544118
Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparumQ30041439
A pathway for phosphatidylcholine biosynthesis in Plasmodium falciparum involving phosphoethanolamine methylationQ30046703
Delivery of antimicrobials into parasitesQ30493563
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.Q32145030
Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host.Q33770602
The plastid in Apicomplexa: what use is it?Q34038501
Fatty acid and sterol metabolism: potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoaQ34180978
Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondiiQ35016560
Infection with Toxoplasma gondii bradyzoites has a diminished impact on host transcript levels relative to tachyzoite infectionQ35689264
Current progress in the fatty acid metabolism in Cryptosporidium parvumQ35880138
The apicoplast: a review of the derived plastid of apicomplexan parasites.Q35973654
Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometryQ36040256
Insights into unique physiological features of neutral lipids in Apicomplexa: from storage to potential mediation in parasite metabolic activitiesQ36111210
Toxoplasma gondii exploits host low-density lipoprotein receptor-mediated endocytosis for cholesterol acquisitionQ36328217
Contribution of host lipids to Toxoplasma pathogenesisQ36347850
Synthesis of chloroplast galactolipids in apicomplexan parasitesQ39618500
Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4.Q40183064
Identification and quantification of glycerolipids in cotton fibers: reconciliation with metabolic pathway predictions from DNA databases.Q40371763
Toxoplasma gondii acyl-lipid metabolism: de novo synthesis from apicoplast-generated fatty acids versus scavenging of host cell precursorsQ42044425
Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivoQ42663544
Formation of ceramide phosphorylethanolamine from phosphatidylethanolamine in the rumen protozoon Entodinium caudatum (Short Communication).Q42923935
Isolation of ceramide phosphorylethanolamine from the blowfly Calliphora erythrocephalaQ42952614
Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondiiQ43678703
Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii.Q44064141
High-throughput quantification of phosphatidylcholine and sphingomyelin by electrospray ionization tandem mass spectrometry coupled with isotope correction algorithmQ45136777
Selective disruption of phosphatidylcholine metabolism of the intracellular parasite Toxoplasma gondii arrests its growthQ45263588
Synthesis and antimalarial activity of new 1,12-bis(N,N'-acetamidinyl)dodecane derivativesQ48036841
Occurrence and biosynthesis of ceramide phosphorylethanolamine in chicken and rat liver.Q48796713
Evidence for the biosynthesis of ceramide-phosphoethanolamine in brain synaptic plasma membrane vesicles and in sciatic nerve microsomes from normal and Trembler mice.Q48878460
Profiling Membrane Lipids in Plant Stress ResponsesQ56623372
Fatty acid synthesis by elongases in trypanosomesQ61514515
Physical properties of membranes isolated from tissue culture cells with altered phospholipid compositionQ67835326
Characterization of the lipid content ofToxoplasma gondiirhoptriesQ67935646
Metabolism of ceramide phosphorylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidylglycerol by housefly larvaeQ68633167
Structure and thermotropic properties of phosphatidylethanolamine and its N-methyl derivativesQ70613270
Thermotropic behavior of bilayers formed from mixed-chain phosphatidylcholinesQ70720047
Structural elucidation of sphingoethanolamine and its distribution in aquatic animalsQ72132321
Structural determination of sphingomyelin by tandem mass spectrometry with electrospray ionizationQ73735687
Identification of ceramide-phosphorylethanolamine in oomycete plant pathogens: Pythium ultimum, Phytophthora infestans, and Phytophthora capsiciQ74482933
Toxoplasma gondii dysregulates IFN-gamma-inducible gene expression in human fibroblasts: insights from a genome-wide transcriptional profilingQ80088037
P433issue48
P407language of work or nameEnglishQ1860
P921main subjectToxoplasma gondiiQ131003
P304page(s)13882-13890
P577publication date2007-11-08
P1433published inBiochemistryQ764876
P1476titleLipidomic analysis of Toxoplasma gondii reveals unusual polar lipids
P478volume46

Reverse relations

cites work (P2860)
Q36594635A Lipolytic Lecithin:Cholesterol Acyltransferase Secreted by Toxoplasma Facilitates Parasite Replication and Egress
Q35762962Apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in apicomplexan parasite Toxoplasma gondii
Q36094810Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant-Like Glycerol 3-Phosphate Acyltransferase
Q36820112Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites
Q35956728Conditional mutagenesis of a novel choline kinase demonstrates plasticity of phosphatidylcholine biogenesis and gene expression in Toxoplasma gondii
Q34102702Deficiency of a Niemann-Pick, type C1-related protein in toxoplasma is associated with multiple lipidoses and increased pathogenicity
Q36278875Diffusion tensor imaging and myelin composition analysis reveal abnormal myelination in corpus callosum of canine mucopolysaccharidosis I.
Q30576511Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs
Q38668340Everybody needs sphingolipids, right! Mining for new drug targets in protozoan sphingolipid biosynthesis
Q35314031Identification of plant-like galactolipids in Chromera velia, a photosynthetic relative of malaria parasites
Q55385104Lipid analysis of Eimeria sporozoites reveals exclusive phospholipids, a phylogenetic mosaic of endogenous synthesis, and a host-independent lifestyle.
Q37315680Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans
Q26822690Lipidomic profiling of model organisms and the world's major pathogens
Q40156690Mechanism of dexamethasone in the context of Toxoplasma gondii infection
Q35573325Neospora caninum Recruits Host Cell Structures to Its Parasitophorous Vacuole and Salvages Lipids from Organelles
Q90645370Novel Approaches To Kill Toxoplasma gondii by Exploiting the Uncontrolled Uptake of Unsaturated Fatty Acids and Vulnerability to Lipid Storage Inhibition of the Parasite
Q28550943Phosphatidylthreonine and Lipid-Mediated Control of Parasite Virulence
Q64057075Pore-forming protein complexes from Pleurotus mushrooms kill western corn rootworm and Colorado potato beetle through targeting membrane ceramide phosphoethanolamine
Q34489810Quantitation of ceramide phosphorylethanolamines containing saturated and unsaturated sphingoid base cores
Q43120234Separation of DNA-containing organelles from Toxoplasma gondii by CZE.
Q36775799Sphingolipid synthesis and scavenging in the intracellular apicomplexan parasite, Toxoplasma gondii
Q40027175Subcellular localization and dynamics of a digalactolipid-like epitope in Toxoplasma gondii.
Q38155730Targeting lipid biosynthesis and salvage in apicomplexan parasites for improved chemotherapies
Q38795486The antifungal Aureobasidin A and an analogue are active against the protozoan parasite Toxoplasma gondii but do not inhibit sphingolipid biosynthesis
Q37660559The potential of mass spectrometry for the global profiling of parasite metabolomes
Q52313831Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages.
Q38897010Two phylogenetically and compartmentally distinct CDP-diacylglycerol synthases cooperate for lipid biogenesis in Toxoplasma gondii
Q42174607Ultra performance liquid chromatography and high resolution mass spectrometry for the analysis of plant lipids

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