Prostaglandins in experimental syphilis: treponemes stimulate adherent spleen cells to secrete prostaglandin E2, and indomethacin upregulates immune functions

scientific article published on January 1991

Prostaglandins in experimental syphilis: treponemes stimulate adherent spleen cells to secrete prostaglandin E2, and indomethacin upregulates immune functions is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID257718
P698PubMed publication ID1987026

P2093author name stringT Rice
T J Fitzgerald
G J Trachte
M A Tomai
P2860cites workProstaglandin regulation of colony-stimulating factor production by lipopolysaccharide-stimulated murine leukocytesQ34096224
Characterization of the attachment of Treponema pallidum (Nichols strain) to cultured mammalian cells and the potential relationship of attachment to pathogenicityQ34419132
A histopathologic and immunologic study of the course of syphilis in the experimentally infected rabbit. Demonstration of long-lasting cellular immunityQ35863405
Regulation of arachidonic acid metabolism by macrophage activationQ36346374
Suppression of interleukin-2 production by macrophages in genetically susceptible mice infected with Leishmania majorQ37013127
Suppression of cellular immunity to Listeria monocytogenes by activated macrophages: mediation by prostaglandinsQ37050215
Immunosuppression associated with the development of chronic infections with Rickettsia tsutsugamushi: adherent suppressor cell activity and macrophage activationQ37053044
Identification of a membrane-associated interleukin 1 in macrophagesQ37678410
Immune responses during human schistosomiasis mansoni. V. Suppression of schistosome antigen-specific lymphocyte blastogenesis by adherent/phagocytic cellsQ39548656
Lepromin-induced suppressor cells in patients with leprosyQ39893897
The Role of Arachidonic Acid Oxygenation Products in Pain and InflammationQ40081115
Shigella Infection of Henle Intestinal Epithelial Cells: Role of the Host CellQ40245449
The evolution of immunosuppressive cell populations in experimental mycobacterial infectionQ40900938
Demonstration of the in vitro phagocytosis of Treponema pallidum by rabbit peritoneal macrophagesQ40957309
Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal microfilamentsQ41182472
Chronic infection due to Mycobacterium intracellulare in mice: association with macrophage release of prostaglandin E2 and reversal by injection of indomethacin, muramyl dipeptide, or interferon-gammaQ41364634
Characterization of lymphocyte responsiveness in early experimental syphilis. I. In vitro response to mitogens and Treponema pallidum antigensQ41537539
Soluble factors from rabbit spleen cells kill and lyse Treponema pallidum in vitroQ41718972
Thymoma production of T cell growth factor (Interleukin 2).Q42800297
Characterization of anti-treponemal lymphotoxin from lymphocytes of syphilitic rabbitsQ43579615
Experimental cutaneous leishmaniasis. II. A possible role for prostaglandins in exacerbation of disease in Leishmania major-infected BALB/c mice.Q43934109
Release of leukotrienes C4 and B4 and prostaglandin E2 from human monocytes stimulated with aggregated IgG, IgA, and IgE.Q44725950
Immunologic deficiency during experimental Chagas' disease (Trypanosoma cruzi infection): role of adherent, nonspecific esterase-positive splenic cellsQ58847386
Identification of cells producing anti-treponemal lymphotoxin (ATL)Q68186794
Phagocytosis of Treponema pallidum pertenue by hamster macrophages on membrane filtersQ69522730
Macrophage-mediated suppression of con A-induced IL-2 production in spleen cells from syphilitic rabbitsQ69739748
Detection and functional characterization of early appearing antibodies in rabbits with experimental syphilisQ69888671
Arachidonic acid metabolism by murine peritoneal macrophages infected with Leishmania donovani: in vitro evidence for parasite-induced alterations in cyclooxygenase and lipoxygenase pathwaysQ69936533
Regulation of macrophage-derived fibroblast growth factor release by arachidonate metabolitesQ70183407
Experimental syphilitic orchitis in rabbits: ultrastructural appearance of Treponema pallidum during phagocytosis and dissolution by macrophages in vivoQ70226796
Prostaglandins as endogenous mediators of interleukin 1 productionQ70274562
Humoral immune response in experimental syphilis to polypeptides of Treponema pallidumQ70283188
The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitroQ70312964
C3-mediated release of prostaglandin from human monocytes: evidence for independent regulation of thromboxane and prostaglandin synthesisQ70367234
Antigen-specific suppressor cells and suppressor factors in human filariasis with Brugia malayiQ70523346
Treponemicidal activity of supernatants from cultures of sensitized lymphocytesQ71443452
Characterization of lymphocyte responsiveness in early experimental syphilis. II. Nature of cellular infiltration and Treponema pallidum distribution in testicular lesionsQ72603802
Monocyte suppression of antigen-specific lymphocyte responses in diffuse cutaneous leishmaniasis patients from the Dominican RepublicQ72730597
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P304page(s)143-149
P577publication date1991-01-01
P1433published inInfection and ImmunityQ6029193
P1476titleProstaglandins in experimental syphilis: treponemes stimulate adherent spleen cells to secrete prostaglandin E2, and indomethacin upregulates immune functions
P478volume59

Reverse relations

cites work (P2860)
Q40147994Evidence that autologous idiotypic regulation of anti-arginine-glycine-aspartic acid autoantibodies may influence development and progression of syphilitic lesions in infected rabbits
Q33595436Long-term study of cell-mediated responses to Borrelia burgdorferi in the laboratory mouse
Q36989255Splenic T-lymphocyte functions during early syphilitic infection are complex
Q35348110The Th1/Th2-like switch in syphilitic infection: is it detrimental?

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