Modeling the interactions of bacteria and Toll-like receptor-mediated inflammation in necrotizing enterocolitis

scientific article published on 10 December 2012

Modeling the interactions of bacteria and Toll-like receptor-mediated inflammation in necrotizing enterocolitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JTBI.2012.12.002
P932PMC publication ID4893796
P698PubMed publication ID23238281
P894zbMATH Open document ID1342.92089

P50authorYoram VodovotzQ90029895
Julia ArcieroQ55315519
P2093author name stringJonathan Rubin
Amin Afrazi
G Bard Ermentrout
David Hackam
Richard Siggers
P2860cites workProbiotics for prevention of necrotizing enterocolitis in preterm infantsQ24235681
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Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitisQ28579439
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Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitisQ30981744
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Oral probiotics prevent necrotizing enterocolitis in very low birth weight preterm infants: a multicenter, randomized, controlled trialQ33440895
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Toll-like receptor-4 inhibits enterocyte proliferation via impaired beta-catenin signaling in necrotizing enterocolitisQ33618589
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Developmentally regulated IkappaB expression in intestinal epithelium and susceptibility to flagellin-induced inflammationQ33905521
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Cytokine elevations in critically ill infants with sepsis and necrotizing enterocolitisQ72712738
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Probiotics feeding in prevention of urinary tract infection, bacterial sepsis and necrotizing enterocolitis in preterm infants. A prospective double-blind studyQ74593416
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Double-blind, randomised clinical assay to evaluate the efficacy of probiotics in preterm newborns weighing less than 1500 g in the prevention of necrotising enterocolitisQ84068152
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Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activityQ34381271
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Simple intestinal obstruction causes bacterial translocation in man.Q34530944
Understanding the susceptibility of the premature infant to necrotizing enterocolitis (NEC).Q34586214
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Immature oxidative stress management as a unifying principle in the pathogenesis of necrotizing enterocolitis: insights from an agent-based model.Q35799174
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Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.Q36645036
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Necrotizing enterocolitis in the premature infant: neonatal nursing assessment, disease pathogenesis, and clinical presentationQ37138087
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitisQ37142110
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Role of LPS/CD14/TLR4-mediated inflammation in necrotizing enterocolitis: pathogenesis and therapeutic implicationsQ37386502
Probiotic bacteria and intestinal epithelial barrier functionQ37714234
Critical systematic review of the level of evidence for routine use of probiotics for reduction of mortality and prevention of necrotizing enterocolitis and sepsis in preterm infantsQ37945420
Toll-like receptor 9-dependent macrophage activation by Entamoeba histolytica DNA.Q40055987
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Increased expression and function of integrins in enterocytes by endotoxin impairs epithelial restitutionQ40436297
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Gut microbial translocation in critically ill children and effects of supplementation with pre- and pro bioticsQ42014198
Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-culturesQ42018332
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Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic miceQ44760599
Circulating pro- and counterinflammatory cytokine levels and severity in necrotizing enterocolitisQ44857687
State-based analysis of necrotizing enterocolitis outcomesQ46471908
Probiotic supplement reduces risk of necrotizing enterocolitis and mortality in preterm very low-birth-weight infants: an updated meta-analysis of 20 randomized, controlled trialsQ47332291
Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonatesQ47370646
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A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation.Q51944707
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair.Q53526875
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P6104maintained by WikiProjectWikiProject MathematicsQ8487137
P1104number of pages17
P304page(s)83-99
P577publication date2012-12-10
P1433published inJournal of Theoretical BiologyQ2153724
P1476titleModeling the interactions of bacteria and Toll-like receptor-mediated inflammation in necrotizing enterocolitis
P478volume321

Reverse relations

cites work (P2860)
Q57162277An enhanced Lactobacillus reuteri biofilm formulation that increases protection against experimental necrotizing enterocolitis
Q38256973Computational modelling of the inflammatory response in trauma, sepsis and wound healing: implications for modelling resilience
Q47691807Host-microbe interaction in the gastrointestinal tract.
Q38730870Inflammation and Apoptosis: Dual Mediator Role for Toll-like Receptor 4 in the Development of Necrotizing Enterocolitis
Q28081320Insights into the Role of Chemokines, Damage-Associated Molecular Patterns, and Lymphocyte-Derived Mediators from Computational Models of Trauma-Induced Inflammation
Q92000401Irf5 deficiency in myeloid cells prevents necrotizing enterocolitis by inhibiting M1 macrophage polarization
Q40259205Mesenchymal stem cells cannot affect mRNA expression of toll-like receptors in different tissues during sepsis.
Q53202442Paneth cells in the developing gut: when do they arise and when are they immune competent?
Q39035255Pathogenesis of NEC: Role of the innate and adaptive immune response.
Q98778637Safety and efficacy of probiotic administration to preterm infants: ten common questions
Q47765179Stem cell therapy in necrotizing enterocolitis: Current state and future directions
Q41521521mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis

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