Lack of "hemichannel" activity in insulin-producing cells

scientific article published on May 2008

Lack of "hemichannel" activity in insulin-producing cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/15419060802014255
P932PMC publication ID2583242
P698PubMed publication ID18649186
P5875ResearchGate publication ID51422837

P2093author name stringAnne Charollais
Eliana Scemes
Paolo Meda
David C Spray
Sabine Bavamian
P2860cites workPannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptorQ24306745
A ubiquitous family of putative gap junction moleculesQ28140991
Pannexin membrane channels are mechanosensitive conduits for ATPQ28276454
Pannexins, a family of gap junction proteins expressed in brainQ28567263
Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytesQ28568971
Functional connexin “hemichannels”: A critical appraisalQ29030321
Emerging issues of connexin channels: biophysics fills the gap.Q30167614
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complexQ30479449
Beyond the gap: functions of unpaired connexon channelsQ33186594
Pannexin 1 in erythrocytes: function without a gapQ34650659
Visualization and functional blocking of gap junction hemichannels (connexons) with antibodies against external loop domains in astrocytesQ34750442
Gap junction channel gatingQ35700096
Mechanisms of glutamate release from astrocytes: gap junction "hemichannels", purinergic receptors and exocytotic release.Q35774444
Connexins: functions without junctionsQ35885621
Connexin-based gap junction hemichannels: gating mechanismsQ36162607
Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cellsQ36237240
Physiological role of gap-junctional hemichannels. Extracellular calcium-dependent isosmotic volume regulationQ36327016
Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaquesQ36530637
Physiology and pathophysiology of purinergic neurotransmissionQ36788894
Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes.Q40457389
Connexin 36 controls synchronization of Ca2+ oscillations and insulin secretion in MIN6 cells.Q40675575
Metabolic inhibition activates a non-selective current through connexin hemichannels in isolated ventricular myocytes.Q40851897
Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration.Q42075014
Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.Q42478852
Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kineticsQ42510377
A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cellsQ42524501
Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calciumQ46858670
Functional properties of channels formed by the neuronal gap junction protein connexin36.Q52137784
Hemi-gap-junction channels in solitary horizontal cells of the catfish retina.Q54280754
Stable and diffusible pools of nucleotides in pancreatic islet cellsQ71733313
Comparison of lucifer yellow leakage and cell-to-cell transfer following intracellular injection in normal and antisense Novikoff cells under treatment with low extracellular Ca2+Q73097753
Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channelsQ81166280
P433issue1
P304page(s)143-154
P577publication date2008-05-01
P1433published inCell Communication & AdhesionQ15709519
P1476titleLack of "hemichannel" activity in insulin-producing cells
P478volume15

Reverse relations

cites work (P2860)
Q34249054Activation, permeability, and inhibition of astrocytic and neuronal large pore (hemi)channels
Q26824824Connexin hemichannel and pannexin channel electrophysiology: how do they differ?
Q35578551Connexins protect mouse pancreatic β cells against apoptosis.
Q37130086Connexins, pannexins, innexins: novel roles of "hemi-channels"
Q37947566Connexins: key mediators of endocrine function
Q36598549High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y(13) receptor
Q48604170Inhibition of connexin 36 hemichannels by glucose contributes to the stimulation of insulin secretion
Q37732539New insights into the role of connexins in pancreatic islet function and diabetes.
Q37287798Protein-mediated interactions of pancreatic islet cells