Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice

scholarly article

Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2008PNAS..10519944B
P356DOI10.1073/PNAS.0808116105
P932PMC publication ID2588415
P698PubMed publication ID19036930
P5875ResearchGate publication ID23500739

P50authorTimothy P SheahanQ88410103
Amy C SimsQ88410106
Eric DonaldsonQ90822619
Barry RockxQ92024521
Raymond J PicklesQ114519286
Mark R. DenisonQ56426185
Rachel L. GrahamQ56863434
Ralph S. BaricQ63881333
P2093author name stringMichelle M Becker
Robert E Johnston
Davide Corti
P2860cites workThe molecular biology of coronavirusesQ93899306
Reconstitution of an infectious human endogenous retrovirusQ21559512
Host range and emerging and reemerging pathogensQ24273386
Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe batsQ24536078
Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotidesQ24618245
The SARS coronavirus S glycoprotein receptor binding domain: fine mapping and functional characterizationQ24817089
Bats: important reservoir hosts of emerging virusesQ27473464
Viral evolution and the emergence of SARS coronavirusQ27477755
Structural basis of viral invasion: lessons from paramyxovirus FQ27481675
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2Q28191005
Coronavirus as a possible cause of severe acute respiratory syndromeQ28200848
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genomeQ28265807
Bats are natural reservoirs of SARS-like coronavirusesQ28274751
Characterization of the reconstructed 1918 Spanish influenza pandemic virusQ28275911
Detection of group 1 coronaviruses in bats in North AmericaQ28752516
Identification of a novel coronavirus in patients with severe acute respiratory syndromeQ29615907
A novel coronavirus associated with severe acute respiratory syndromeQ29617553
Isolation and characterization of viruses related to the SARS coronavirus from animals in southern ChinaQ29618055
NCBI Reference Sequence project: update and current statusQ30722205
Social and environmental risk factors in the emergence of infectious diseasesQ30977705
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c miceQ33269158
Retargeting of coronavirus by substitution of the spike glycoprotein ectodomain: crossing the host cell species barrierQ33793489
Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural templateQ33960127
Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farmsQ33987404
The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replicationQ34092836
Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungsQ34228602
Structure of SARS coronavirus spike receptor-binding domain complexed with receptorQ34451350
Switching species tropism: an effective way to manipulate the feline coronavirus genomeQ34857052
Antibodies to SARS coronavirus in civetsQ35881133
Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged miceQ35914462
Amino acid substitutions in the S2 subunit of mouse hepatitis virus variant V51 encode determinants of host range expansionQ36424092
Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactionsQ36447896
Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat originQ36483269
Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epitheliumQ36483886
Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challengeQ36498144
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirusQ36690054
A translation-attenuating intraleader open reading frame is selected on coronavirus mRNAs during persistent infectionQ36724120
Emerging viruses: coming in on a wrinkled wing and a prayerQ36728070
A review of studies on animal reservoirs of the SARS coronavirusQ36798770
Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteinsQ37492491
The N-terminal region of the murine coronavirus spike glycoprotein is associated with the extended host range of viruses from persistently infected murine cellsQ39756274
A single amino acid substitution in the S1 and S2 Spike protein domains determines the neutralization escape phenotype of SARS-CoV.Q40073664
Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strainQ40090304
The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2.Q40106974
Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.Q40163145
Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonistsQ40208162
7a protein of severe acute respiratory syndrome coronavirus inhibits cellular protein synthesis and activates p38 mitogen-activated protein kinaseQ40335972
Mosaic evolution of the severe acute respiratory syndrome coronavirusQ40377013
Is CD46 the cellular receptor for measles virus?Q41461720
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membraneQ42624738
Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2.Q42844863
Animal models and vaccines for SARS-CoV infectionQ43152086
Molecular constraints to interspecies transmission of viral pathogensQ43218456
Is there an ideal animal model for SARS?Q51806996
P433issue50
P407language of work or nameEnglishQ1860
P921main subjectCoronaviridaeQ1134583
SARSr-CoVQ278567
SARS-CoV-1Q85438966
bat coronavirusQ88099582
P304page(s)19944-19949
P577publication date2008-11-26
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSynthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
P478volume105

Reverse relations

cites work (P2860)
Q36702376A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
Q36281179A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection
Q30374709A comprehensive collection of systems biology data characterizing the host response to viral infection.
Q98623621A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction
Q28817689A decade after SARS: strategies for controlling emerging coronaviruses
Q35531454A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge
Q36456720A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease
Q30360627A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant
Q31126174A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses
Q27490484A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
Q93028017Advances in respiratory virus therapeutics - A meeting report from the 6th isirv Antiviral Group conference
Q39730973An inactivated West Nile Virus vaccine derived from a chemically synthesized cDNA system
Q91610063An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
Q95315888Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection
Q37713866Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity
Q96302798Bat-borne virus diversity, spillover and emergence
Q42258730Bats as animal reservoirs for the SARS coronavirus: hypothesis proved after 10 years of virus hunting
Q38665457Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.
Q84315401Broad-spectrum coronavirus antiviral drug discovery
Q103836662Building genomes to understand biology
Q91717735COVID-19: Risk Groups, Mechanistic Insights, and Challenges
Q41921793Cloning, Assembly, and Modification of the Primary Human Cytomegalovirus Isolate Toledo by Yeast-Based Transformation-Associated Recombination.
Q30244811Coronavirus Spike Protein and Tropism Changes
Q34663663Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments
Q34233548Coronavirus pathogenesis
Q26863163Coronavirus reverse genetic systems: infectious clones and replicons
Q33694361Coronaviruses post-SARS: update on replication and pathogenesis
Q35079166Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity
Q30250231Deciphering the biology of porcine epidemic diarrhea virus in the era of reverse genetics.
Q98720898Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
Q34184711Development and characterization of a reverse genetic system for studying dengue virus serotype 3 strain variation and neutralization
Q34983662Differential sensitivity of bat cells to infection by enveloped RNA viruses: coronaviruses, paramyxoviruses, filoviruses, and influenza viruses
Q36931120Differentiated phenotypes of primary murine alveolar epithelial cells and their susceptibility to infection by respiratory viruses
Q33644581Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana
Q24337838Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus
Q30355171Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS.
Q40200075Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses
Q37962354Emerging biomedical applications of synthetic biology
Q37174550Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate
Q58596644Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform
Q37635133Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses
Q36023052Evidence for ACE2-utilizing coronaviruses (CoVs) related to severe acute respiratory syndrome CoV in bats
Q28712758Evidence supporting a zoonotic origin of human coronavirus strain NL63
Q90632605Evolutionary Trajectory for the Emergence of Novel Coronavirus SARS-CoV-2
Q96641812For a better world: Biosafety strategies to protect global health
Q89866691Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
Q84082454Functional assessment of cell entry and receptor usage for lineage B β-coronaviruses, including 2019-nCoV
Q41012567Functional properties and genetic relatedness of the fusion and hemagglutinin-neuraminidase proteins of a mumps virus-like bat virus
Q30400728Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus
Q28748910Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences
Q84315382Geographical structure of bat SARS-related coronaviruses
Q64091639Harnessed viruses in the age of metagenomics and synthetic biology: an update on infectious clone assembly and biotechnologies of plant viruses
Q84316162Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China
Q33743774Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome-like coronavirus from bats in China
Q39436807Identification of immunogenic determinants of the spike protein of SARS-like coronavirus
Q39826024Immunogenicity difference between the SARS coronavirus and the bat SARS-like coronavirus spike (S) proteins.
Q40293033Immunogenicity of a multi-epitope DNA vaccine against hantavirus
Q36154930Increased antibody affinity confers broad in vitro protection against escape mutants of severe acute respiratory syndrome coronavirus
Q33576672Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing
Q93221320Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
Q90465443Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics?
Q30219701Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor
Q30235867Jumping species-a mechanism for coronavirus persistence and survival
Q34417984Large-scale de novo DNA synthesis: technologies and applications
Q34416671Metagenomic analysis of the viromes of three North American bat species: viral diversity among different bat species that share a common habitat
Q34282268Methods and applications for assembling large DNA constructs
Q57094095Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice
Q87747946Origin and evolution of pathogenic coronaviruses
Q33813376Proof by synthesis of Tobacco mosaic virus
Q36509100Protecting society. Biological security and dual-use dilemma in the life sciences--status quo and options for the future
Q43692542Public health: Broad reception for coronavirus
Q24650468Putting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesis
Q33963398RNA virus reverse genetics and vaccine design.
Q35943657Ready, set, fuse! The coronavirus spike protein and acquisition of fusion competence
Q38133141Receptor recognition and cross-species infections of SARS coronavirus
Q88974047Recombination and lineage-specific mutations led to the emergence of SARS-CoV-2
Q37631303Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission
Q38254831Reprint of: Coronavirus reverse genetic systems: infectious clones and replicons.
Q88046426Return of the Coronavirus: 2019-nCoV
Q37218442Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
Q30249325SARS and MERS: recent insights into emerging coronaviruses
Q35612506SARS-CoV and emergent coronaviruses: viral determinants of interspecies transmission
Q60949221SARS-Like Coronavirus WIV1-CoV Does Not Replicate in Egyptian Fruit Bats ()
Q40375905Surveillance of Bat Coronaviruses in Kenya Identifies Relatives of Human Coronaviruses NL63 and 229E and Their Recombination History
Q34073961Synthetic biology for translational research
Q59267606Synthetic biology: From the first synthetic cell to see its current situation and future development
Q33958771Synthetic biology: applications come of age
Q28729206Synthetic constructs in/for the environment: managing the interplay between natural and engineered Biology
Q28706666Synthetic genomics and synthetic biology applications between hopes and concerns
Q57566541Synthetic genomics: a new venture to dissect genome fundamentals and engineer new functions
Q57031417Synthetic viruses-Anything new?
Q24650817Synthetic viruses: a new opportunity to understand and prevent viral disease
Q38718445The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination
Q37542425The impact of synthetic biology on drug discovery
Q58494157The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species
Q37246874The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokines
Q91697408Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection
Q37783762Update on SARS research and other possibly zoonotic coronaviruses
Q47253371Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Search more.