Lipocalin 2, a Regulator of Retinoid Homeostasis and Retinoid-mediated Thermogenic Activation in Adipose Tissue

scientific article published on 22 March 2016

Lipocalin 2, a Regulator of Retinoid Homeostasis and Retinoid-mediated Thermogenic Activation in Adipose Tissue is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.711556
P932PMC publication ID4900269
P698PubMed publication ID27008859

P50authorDavid A BernlohrQ88156964
P2093author name stringHong Guo
Yuanyuan Zhang
Hongfeng Jiang
Xiaoli Chen
William S Blaner
Sheila M O'Byrne
Rocio Foncea
Jessica A Deis
P2860cites workNeutrophil gelatinase-associated lipocalin mediates 13-cis retinoic acid-induced apoptosis of human sebaceous gland cellsQ24657556
Structure and sequence relationships in the lipocalins and related proteinsQ24675786
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A membrane receptor for retinol binding protein mediates cellular uptake of vitamin AQ28285192
STRA6, a cell-surface receptor for retinol-binding protein: the plot thickensQ28291548
Brown adipose tissue: function and physiological significanceQ29547448
Adipokines in inflammation and metabolic diseaseQ29620456
The up-and-down beta-barrel proteinsQ30193828
Remodeling of white adipose tissue after retinoic acid administration in miceQ79903086
Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL.Q33412995
All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.Q33558905
Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometryQ33862174
Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in miceQ33869748
Investigating diversity in human plasma proteinsQ33905685
Lipocalin 2 regulates brown fat activation via a nonadrenergic activation mechanismQ34070383
Beyond the superfamily: the lipocalin receptorsQ34073711
Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptorsQ34491403
Comparative ligand-binding analysis of ten human lipocalinsQ34491841
Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditureQ34502676
Signaling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasisQ35478457
The implication of brown adipose tissue for humansQ35502624
Quantitative measurement of full-length and C-terminal proteolyzed RBP4 in serum of normal and insulin-resistant humans using a novel mass spectrometry immunoassayQ35762679
All-trans-retinol is a ligand for the retinoic acid receptorsQ36460690
The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages.Q36710165
RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndromeQ36922692
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Evidence for the regulatory role of lipocalin 2 in high-fat diet-induced adipose tissue remodeling in male miceQ37181894
All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptorQ37233353
Retinoic acid: A key player in immunityQ37783965
Positive and negative control of Ucp1 gene transcription and the role of β-adrenergic signaling networksQ37799247
Lipid metabolism in mammalian tissues and its control by retinoic acidQ37888873
Retinol-binding protein: the serum transport protein for vitamin A.Q38287150
Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gammaQ38356172
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Retinyl ester hydrolysis and retinol efflux from BFC-1beta adipocytesQ41108995
In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acidQ41181250
A complex retinoic acid response element in the uncoupling protein gene defines a novel role for retinoids in thermogenesisQ41181697
An apparent autocrine mechanism amplifies the dexamethasone- and retinoic acid-induced expression of mouse lipocalin-encoding gene 24p3.Q41199368
Plasma Delivery of Retinoic Acid to Tissues in the RatQ41323313
Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesisQ42488444
The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistanceQ42826437
Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes.Q44203920
Retinoids and retinoid-binding protein expression in rat adipocytesQ53850083
Essentialcis-Acting Elements in Rat Uncoupling Protein Gene Are in an Enhancer Containing a Complex Retinoic Acid Response DomainQ59504027
A Novel Regulatory Pathway of Brown Fat ThermogenesisQ60636934
Opposite effects of feeding a vitamin A-deficient diet and retinoic acid treatment on brown adipose tissue uncoupling protein 1 (UCP1), UCP2 and leptin expressionQ61316822
Effect of Low Environmental Temperature on the Metabolism of Vitamin A (Retinol) in the RatQ72308485
Dietary vitamin A supplementation in rats: suppression of leptin and induction of UCP1 mRNAQ77388330
Properties of retinoids. Structure, handling, and preparationQ77571579
Stimulation of uncoupling protein 1 expression in brown adipocytes by naturally occurring carotenoidsQ78015426
Insulin-induced up-regulated uncoupling protein-1 expression is mediated by insulin receptor substrate 1 through the phosphatidylinositol 3-kinase/Akt signaling pathway in fetal brown adipocytesQ78785297
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)11216-11229
P577publication date2016-03-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleLipocalin 2, a Regulator of Retinoid Homeostasis and Retinoid-mediated Thermogenic Activation in Adipose Tissue
P478volume291

Reverse relations

cites work (P2860)
Q38674243Aldehyde dehydrogenase 1 a1 regulates energy metabolism in adipocytes from different species
Q37681747Chronic alcohol consumption decreases brown adipose tissue mass and disrupts thermoregulation: a possible role for altered retinoid signaling.
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Q98944918Lipocalin-2 deficiency may predispose to the progression of spontaneous age-related adiposity in mice
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Q90291800Nutritional and non-nutritional agents that stimulate white adipose tissue browning
Q91643832miRNAs and Novel Food Compounds Related to the Browning Process

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