Small-animal model to measure efficacy and immunogenicity of Shigella vaccine strains

scientific article published on November 1991

Small-animal model to measure efficacy and immunogenicity of Shigella vaccine strains is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.59.11.4075-4083.1991
P932PMC publication ID258999
P698PubMed publication ID1937767

P2093author name stringOaks EV
Eckels KH
Schultz CL
Hartman AB
Powell CJ
P2860cites workConstruction of an auxotrophic Shigella flexneri strain for use as a live vaccine.Q54712481
Serum antibodies to lipopolysaccharide and natural immunity to shigellosis in an Israeli military populationQ68134308
Local and systemic antibody responses to Shigella infection in rhesus monkeysQ68944588
Immunity in Shigellosis. II. Protection Induced by Oral Live Vaccine or Primary InfectionQ69156182
Immunity to keratoconjunctivitis shigellosa in rabbits after oral immunization with Shigella sonnei free endotoxinQ69362834
Vaccine strain Sh. flexneri T32-Istrati. Studies in animals and in volunteers. Antidysentery immunoprophylaxis and immunotherapy by live vaccine Vadizen (Sh. flexneri T32-Istrati)Q70422370
Studies in shigellosis. III. A controlled evaluation of a monovalent Shigella vaccine in a highly endemic environmentQ78615786
Acquired natural immunity following recovery from keratoconjunctivitis shigellosaQ78914365
The use of the guinea-pig conjunctivae as an experimental model for the study of virulence of Shigella organismsQ79064584
A new method for the measurement of protective potency of dysentery vaccinesQ79415761
???Q94264873
Sequence and molecular characterization of a multicopy invasion plasmid antigen gene, ipaH, of Shigella flexneriQ33253819
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine developmentQ33628356
Characterization of invasion plasmid antigen genes (ipaBCD) from Shigella flexneriQ33682684
Studies on vaccination against bacillary dysentery. 6. Protection of children by oral immunization with streptomycin-dependent Shigella strainsQ36720620
Specific immunoglobulin A-secreting cells in peripheral blood of humans following oral immunization with a bivalent Salmonella typhi-Shigella sonnei vaccine or infection by pathogenic S. sonneiQ36985066
Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella sppQ37010733
Development of an auxotrophic oral live Shigella flexneri vaccineQ39227963
Oral vaccination of monkeys with an invasive Escherichia coli K-12 hybrid expressing Shigella flexneri 2a somatic antigenQ40168452
Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosisQ40211202
Protection against keratoconjunctivitis shigellosa induced by immunization with outer membrane proteins of Shigella spp.Q41186719
Hybrid vaccines using Escherichia coli as an antigen carrierQ41511130
Studies on vaccination against bacillary dysentery. 2. Safety tests and reactogenicity studies on a live dysentery vaccine intended for use in field trialsQ42175413
Studies on vaccination against bacillary dysentery. 4. Oral immunization with live monotypic and combined vaccinesQ42966608
Construction and evaluation of a double mutant of Shigella flexneri as a candidate for oral vaccination against shigellosisQ44965347
Construction of aromatic dependent Shigella flexneri 2a live vaccine candidate strains: deletion mutations in the aroA and the aroD genesQ46853037
Failure of parenteral vaccines to protect monkeys against experimental shigellosisQ47710064
Prevention of shigellosis by a Salmonella typhi-Shigella sonnei bivalent vaccineQ50201269
Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease.Q50464343
Live Shigella flexneri 2a and Shigella sonnei I vaccine candidate strains with two attenuating markers. I. Construction of vaccine candidate strains with retained invasiveness but reduced intracellular multiplication.Q54331405
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)4075-4083
P577publication date1991-11-01
P1433published inInfection and ImmunityQ6029193
P1476titleSmall-animal model to measure efficacy and immunogenicity of Shigella vaccine strains
P478volume59

Reverse relations

cites work (P2860)
Q40126474An attenuated Shigella mutant lacking the RNA-binding protein Hfq provides cross-protection against Shigella strains of broad serotype.
Q46174437An environmental Escherichia albertii strain, DM104, induces protective immunity to Shigella dysenteriae in guinea pig eye model
Q34941041Analysis of virulence and inflammatory potential of Shigella flexneri purine biosynthesis mutants
Q35411990Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection.
Q52337397Assembly, Biochemical Characterization, Immunogenicity, Adjuvanticity, and Efficacy of Shigella Artificial Invaplex.
Q36844719Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road
Q91801457Consensus Report on Shigella Controlled Human Infection Model: Conduct of Studies
Q35548702Construction and characterization of a live attenuated vaccine candidate against Shigella dysenteriae type 1.
Q39573053Construction of a stable attenuated Shigella sonnei DeltavirG vaccine strain, WRSS1, and protective efficacy and immunogenicity in the guinea pig keratoconjunctivitis model
Q39655324Construction, characterization, and animal testing of WRSd1, a Shigella dysenteriae 1 vaccine
Q46938617Development and evaluation of a Shigella flexneri 2a and S. sonnei bivalent invasin complex (Invaplex) vaccine
Q37643320Development and preclinical evaluation of a trivalent, formalin-inactivated Shigella whole-cell vaccine.
Q37713347Development of an Aotus nancymaae model for Shigella Vaccine immunogenicity and efficacy studies
Q42262595Evaluation of virulent and live Shigella sonnei vaccine candidates in a gnotobiotic piglet model
Q42701095Immunogenic evaluation of chimeric recombinant protein against ETEC, EHEC and Shigella
Q40460000Immunogenicity and characterization of WRSF2G11: a second generation live attenuated Shigella flexneri 2a vaccine strain.
Q40123700Immunogenicity and efficacy of highly purified invasin complex vaccine from Shigella flexneri 2a.
Q40267400Immunogenicity and efficacy of oral or intranasal Shigella flexneri 2a and Shigella sonnei proteosome-lipopolysaccharide vaccines in animal models.
Q50176712Improving chances for successful clinical outcomes with better preclinical models
Q39569905Intracellular multiplication and virulence of Shigella flexneri auxotrophic mutants.
Q33454924Involvement of RNA-binding protein Hfq in the osmotic-response regulation of invE gene expression in Shigella sonnei
Q39517102Isolation and characterization of a Shigella flexneri invasin complex subunit vaccine
Q35772614Local immune response and protection in the guinea pig keratoconjunctivitis model following immunization with Shigella vaccines.
Q34006071Parameters underlying successful protection with live attenuated mutants in experimental shigellosis
Q38294092Safety and colonization of two novel VirG(IcsA)-based live Shigella sonnei vaccine strains in rhesus macaques (Macaca mulatta)
Q84592118Safety and immunogenicity of an intranasal Shigella flexneri 2a Invaplex 50 vaccine
Q36945836Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen.
Q39516481Shigella flexneri IpaH(7.8) facilitates escape of virulent bacteria from the endocytic vacuoles of mouse and human macrophages
Q35227831Specificity of monoclonal antibodies elicited by mucosal infection of BALB/c mice with virulent Shigella flexneri 2a
Q34518265Status of vaccine research and development for Shigella
Q34000330Strategy for cross-protection among Shigella flexneri serotypes
Q39836106Temperature-regulated expression of outer membrane proteins in Shigella flexneri
Q40300987The Galleria mellonella larvae as an in vivo model for evaluation of Shigella virulence.
Q33876803Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602
Q33557800Virulence, inflammatory potential, and adaptive immunity induced by Shigella flexneri msbB mutants

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