The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila

scientific article published on May 2008

The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CMET.2008.02.010
P932PMC publication ID3704161
P698PubMed publication ID18460334
P5875ResearchGate publication ID5393313

P50authorPablo E. SchilmanQ39436350
P2093author name stringJian Chen
Dan Garza
Marc Montminy
Biao Wang
John B Thomas
Jason Goode
Jennifer Best
Jodi Meltzer
P2860cites workCooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expressionQ24304641
A clock gene, period, plays a key role in long-term memory formation in DrosophilaQ24560018
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cellsQ24676703
Expression of Drosophila FOXO regulates growth and can phenocopy starvationQ24794099
The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signalingQ24794823
Targeted gene expression as a means of altering cell fates and generating dominant phenotypesQ27861039
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate proteinQ28211215
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detectorQ28285140
Biological control through regulated transcriptional coactivatorsQ28287472
Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteinsQ28297556
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolismQ28594811
A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fosQ33771493
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligandsQ33863373
A stable genomic source of P element transposase in Drosophila melanogaster.Q33953857
The Ca(2+)-calmodulin-activated protein phosphatase calcineurin negatively regulates EGF receptor signaling in Drosophila development.Q34615078
Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogasterQ34644582
Salt-inducible kinase in steroidogenesis and adipogenesisQ35615336
Prandiology of Drosophila and the CAFE assay.Q35854804
Role of insulin-like signalling in Drosophila lifespanQ36782466
Thermolimit respirometry: an objective assessment of critical thermal maxima in two sympatric desert harvester ants, Pogonomyrmex rugosus and P. californicus.Q39179524
Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent responseQ39687427
Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathwayQ39896136
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.Q40084257
Dephosphorylation of TORC initiates expression of the StAR geneQ40185574
Ablation of insulin-producing neurons in flies: growth and diabetic phenotypesQ43988822
Rapid determination of glycogen and sugars in mosquitoesQ44149355
Rapid determination of total lipids in mosquitoes.Q44149362
Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevityQ44274288
Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cellsQ45062201
The role of cAMP response element-binding protein in Drosophila long-term memory.Q45094906
Regulatory role of dADAR in ROS metabolism in Drosophila CNS.Q45142178
Metabolic reserves and evolved stress resistance in Drosophila melanogasterQ46566190
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly.Q46626387
A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasisQ47071522
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.Q47072330
Thioredoxin-2 affects lifespan and oxidative stress in DrosophilaQ47072718
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liverQ48386175
The Drosophila dCREB2 gene affects the circadian clock.Q52034083
Transgenic cAMP response element reporter flies for monitoring circadian rhythms.Q52656504
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO.Q52674016
P433issue5
P921main subjectDrosophilaQ312154
preproinsulinQ7240673
Salt-inducible kinase 2 Dmel_CG4290Q29820527
P304page(s)434-444
P577publication date2008-05-01
P1433published inCell MetabolismQ1254684
P1476titleThe insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila
P478volume7

Reverse relations

cites work (P2860)
Q46123280A cell based, high throughput assay for quantitative analysis of Hedgehog pathway activation using a Smoothened activation sensor
Q35086655A hormone-dependent module regulating energy balance
Q46016185Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4.
Q42169591Autophagy is an essential component of Drosophila immunity against vesicular stomatitis virus
Q38069942Brain response to calorie restriction
Q34166530CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
Q37219911CRTC Potentiates Light-independent timeless Transcription to Sustain Circadian Rhythms in Drosophila
Q33709917Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells
Q36647275Cross-Study Comparison Reveals Common Genomic, Network, and Functional Signatures of Desiccation Resistance in Drosophila melanogaster
Q39212995Deregulation of CRTCs in Aging and Age-Related Disease Risk
Q35806696Dietary restriction and aging in rodents: a current view on its molecular mechanisms
Q39659088Downregulation of SIK2 expression promotes the melanogenic program in mice
Q37355975Drosophila FoxO regulates organism size and stress resistance through an adenylate cyclase.
Q52609008Drosophila as a Model to Study the Link between Metabolism and Cancer.
Q34509394Drosophila salt-inducible kinase (SIK) regulates starvation resistance through cAMP-response element-binding protein (CREB)-regulated transcription coactivator (CRTC).
Q39763233Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.
Q33428404Expression and regulated nuclear transport of transducers of regulated CREB 1 in retinal ganglion cells
Q47921570Fasting launches CRTC to facilitate long-term memory formation in Drosophila.
Q28547387Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila
Q27312401Feeding state, insulin and NPR-1 modulate chemoreceptor gene expression via integration of sensory and circuit inputs
Q26777821Hormonal Regulation of Response to Oxidative Stress in Insects-An Update
Q42904934Hunger and memory; CRTC coordinates long-term memory with the physiological state, hunger
Q41878718Induction of vertebrate regeneration by a transient sodium current.
Q50779640Integration of taste and calorie sensing in Drosophila.
Q34291303Involvement of SIK3 in glucose and lipid homeostasis in mice
Q33735555Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription.
Q36485301Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2
Q94311615Metabolism: TORCing neurons to maintain blood glucose
Q37650752Molecular mechanisms of metabolic regulation by insulin in Drosophila
Q36025064Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance
Q33525405Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element
Q33521215Regulation of energy stores and feeding by neuronal and peripheral CREB activity in Drosophila
Q90340663Role of CRTC2 in Metabolic Homeostasis: Key Regulator of Whole-Body Energy Metabolism?
Q33936173Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation
Q24295146SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer
Q38924573Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer
Q35646102Salt-inducible kinase is involved in the regulation of corticotropin-releasing hormone transcription in hypothalamic neurons in rats
Q36274871Salt-inducible kinases mediate nutrient-sensing to link dietary sugar and tumorigenesis in Drosophila
Q39221641Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.
Q83228202Sex-specific transcriptomic responses to changes in the nutritional environment
Q37421692Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
Q36347658Signal integration by Ca(2+) regulates intestinal stem-cell activity
Q57849533Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis
Q36863901Targeting sirtuin-1 in Huntington's disease: rationale and current status
Q30439853The Creb1 coactivator Crtc1 is required for energy balance and fertility
Q36969602The EGL-4 PKG acts with KIN-29 salt-inducible kinase and protein kinase A to regulate chemoreceptor gene expression and sensory behaviors in Caenorhabditis elegans
Q90752831The Enigmatic Canal-Associated Neurons Regulate Caenorhabditis elegans Larval Development Through a cAMP Signaling Pathway
Q95841086The Phosphatase CSW Controls Life Span by Insulin Signaling and Metabolism Throughout Adult Life in Drosophila
Q95840788The Role of Peptide Hormones in Insect Lipid Metabolism
Q36167060The distribution of messenger RNAs encoding the three isoforms of the transducer of regulated cAMP responsive element binding protein activity in the rat forebrain
Q28079088The interplay between obesity and cancer: a fly view
Q35124618The molecular physiology of CRH neurons
Q91727068Towards a Better Understanding of Beige Adipocyte Plasticity
Q34418383Transcription control pathways decode patterned synaptic inputs into diverse mRNA expression profiles
Q36379946Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease
Q90317229Triacylglycerol Metabolism in Drosophila melanogaster

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