A role for c-Abl in cell senescence and spontaneous immortalization

scientific article published on July 13, 2012

A role for c-Abl in cell senescence and spontaneous immortalization is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S11357-012-9452-4
P953full work available online athttp://link.springer.com/article/10.1007/s11357-012-9452-4/fulltext.html
http://link.springer.com/content/pdf/10.1007/s11357-012-9452-4
http://link.springer.com/content/pdf/10.1007/s11357-012-9452-4.pdf
https://doi.org/10.1007/s11357-012-9452-4
https://europepmc.org/articles/PMC3705115
https://europepmc.org/articles/pmc3705115?pdf=render
https://europepmc.org/articles/PMC3705115?pdf=render
P932PMC publication ID3705115
P698PubMed publication ID22791394

P2093author name stringXueying Wang
Guang He
Lin He
Min Zhang
Yongyong Shi
Yun Liu
Baojie Li
Huijuan Liu
Man Zhang
Lili Li
Yue Wan
Aijun Hao
Zhongfeng Wang
Junlin Hou
P2860cites workOncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4aQ24324559
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory networkQ27863386
Dual roles of ATM in the cellular response to radiation and in cell growth controlQ52521591
Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null allelesQ52528386
Cellular senescence in aging primatesQ53638045
Mice deficient in Abl are osteoporotic and have defects in osteoblast maturationQ58085524
A role for both RB and p53 in the regulation of human cellular senescenceQ64378339
Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populationsQ70220517
Genomic instability and cancer: an introductionQ83325039
c-Abl: activation and nuclear targetsQ28138395
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINSQ28202269
The Abl family kinases: mechanisms of regulation and signalingQ28206550
Catalase activity is regulated by c-Abl and Arg in the oxidative stress responseQ28207759
p16INK4a induces an age-dependent decline in islet regenerative potentialQ28262230
Accumulation of senescent cells in mitotic tissue of aging primatesQ28274849
Essential roles for the Abl and Arg tyrosine kinases in neurulationQ28504693
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogeneQ28512170
The serial cultivation of human diploid cell strainsQ29547356
Telomeres shorten during ageing of human fibroblastsQ29547357
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageingQ29615155
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 databaseQ29616468
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblastsQ29618748
BRAFE600-associated senescence-like cell cycle arrest of human naeviQ29619550
Cycling, stressed-out and nervous: cellular functions of c-AblQ33632975
p53 and human cancer: the first ten thousand mutations.Q33767112
Cellular senescence: mitotic clock or culture shock?Q34019131
Genes involved in senescence and immortalizationQ34076841
The essence of senescenceQ34288983
Putting the stress on senescenceQ34430830
Tumor suppressor p53 meets microRNAsQ34539766
Oncogenic Braf induces melanocyte senescence and melanoma in miceQ34974162
A positive role for c-Abl in Atm and Atr activation in DNA damage response.Q35092564
Controlling Abl: auto-inhibition and co-inhibition?Q35620042
Regulation of the c-Abl and Bcr-Abl tyrosine kinasesQ35621355
Telomeres, stem cells, senescence, and cancerQ35628573
The BCR-ABL story: bench to bedside and backQ35698382
The signals and pathways activating cellular senescenceQ36060167
Free radicals and senescenceQ37087711
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.Q37345878
Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C deltaQ40014009
Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescenceQ40101245
Identity crisis when telomeres left unprotectedQ41202414
p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblastsQ41654913
c-Abl tyrosine kinase in the DNA damage response: cell death and moreQ42790602
Tumour biology: senescence in premalignant tumoursQ42802962
c-Abl in oxidative stress, aging and cancerQ45227901
p53 Deficiency leads to compensatory up-regulation of p16INK4aQ46110603
Ageing: balancing regeneration and cancerQ48427219
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcellular senescenceQ9075999
developmental gene expression regulationQ70697639
P304page(s)1251-1262
P577publication date2012-07-13
P1433published inAgeQ4691832
P1476titleA role for c-Abl in cell senescence and spontaneous immortalization
P478volume35

Reverse relations

cites work (P2860)
Q38154199An unconventional role of BMP-Smad1 signaling in DNA damage response: a mechanism for tumor suppression
Q41253276P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers
Q33804078c-Abl regulates gastrointestinal muscularis propria homeostasis via ERKs

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