Inhibition of Nod2 signaling and target gene expression by curcumin

scientific article published on 15 April 2008

Inhibition of Nod2 signaling and target gene expression by curcumin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1124/MOL.108.046169
P8608Fatcat IDrelease_dgmq34elvjf2tmvk4lgpg4l7we
P932PMC publication ID2593422
P698PubMed publication ID18413660
P5875ResearchGate publication ID5438361

P2093author name stringDong Seok Lee
Ling Zhao
Daniel H Hwang
Shurong Huang
Kihoon Kim
P2860cites workNod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaBQ22010046
A frameshift mutation in NOD2 associated with susceptibility to Crohn's diseaseQ22251291
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaBQ24290546
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detectionQ24292675
Toll-like receptor signallingQ24570126
Toll-like receptorsQ27860671
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's diseaseQ27860821
An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathwaysQ28139919
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaBQ28142782
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's diseaseQ28201834
Signalling pathways and molecular interactions of NOD1 and NOD2Q28298636
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tractQ28587612
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycanQ29618544
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acidQ29620015
Human Nod1 confers responsiveness to bacterial lipopolysaccharidesQ33923795
Curcumin: the Indian solid goldQ34004696
Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activityQ34416920
NOD-LRR proteins: role in host-microbial interactions and inflammatory diseaseQ34426050
CARD15 mutations in Blau syndromeQ34517310
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groupsQ34735149
Innate immune recognition of microbes through Nod1 and Nod2: implications for diseaseQ35781368
The modulation of inflammatory gene expression by lipids: mediation through Toll-like receptors.Q36472264
Intracellular pattern recognition receptors in the host responseQ36528528
Nod-like proteins in immunity, inflammation and diseaseQ36655897
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognitionQ37544531
Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophagesQ38306709
Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.Q38353590
Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cellsQ40170522
Inhibition of homodimerization of Toll-like receptor 4 by curcuminQ40282987
Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activationQ40362892
Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphomaQ40397270
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activityQ40930583
Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression by inhibiting activator protein 1 and nuclear factor kappab bindings in BV2 microglial cellsQ44810239
Presence of a sporadic case of systemic granulomatosis syndrome with a CARD15 mutationQ47758218
Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]Q71743409
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complexQ73171123
Inhibition of transcription factor NF-kappaB by sesquiterpene lactones: a proposed molecular mechanism of actionQ73346819
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndromeQ80809518
Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kappaBQ80987392
P433issue1
P921main subjectcurcuminQ312266
P304page(s)274-281
P577publication date2008-04-15
P1433published inMolecular PharmacologyQ1943386
P1476titleInhibition of Nod2 signaling and target gene expression by curcumin
P478volume74

Reverse relations

cites work (P2860)
Q37288656A neutraceutical by design: the clinical application of curcumin in colonic inflammation and cancer
Q61955082Anti-inflammatory AreneChromium Complexes Acting as Specific Inhibitors of NOD2 Signalling
Q40375193Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.
Q37856995Effects of flavonoids and other polyphenols on inflammation
Q28535051Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway
Q36086859Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
Q37438177Inhibition of pattern recognition receptor-mediated inflammation by bioactive phytochemicals
Q36053581Postprandial Inflammatory Responses and Free Fatty Acids in Plasma of Adults Who Consumed a Moderately High-Fat Breakfast with and without Blueberry Powder in a Randomized Placebo-Controlled Trial
Q58696497Raspberry Polyphenolic Extract Regulates Obesogenic Signals in Hepatocytes
Q48761437Self-Assembled Nano-Immunostimulant for Synergistic Immune Activation.
Q38270942The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling.
Q39069841Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?
Q37631423Troxerutin Attenuates Enhancement of Hepatic Gluconeogenesis by Inhibiting NOD Activation-Mediated Inflammation in High-Fat Diet-Treated Mice

Search more.