Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality.

scientific article published on May 2013

Metabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1164/RCCM.201209-1726OC
P932PMC publication ID3707368
P698PubMed publication ID23471468

P50authorHector R. WongQ37371526
P2093author name stringHans J Vogel
Brent W Winston
Beata Mickiewicz
P2860cites workNitric oxide synthases in mammalsQ24528695
HMDB: a knowledgebase for the human metabolomeQ24655295
Early goal-directed therapy in the treatment of severe sepsis and septic shockQ27860596
Clinical conditions associated with urinary excretion of 2-hydroxybutyric acidQ28320230
The significance and mechanism of an increased serum phenylalanine-tyrosine ratio during infectionQ28330147
An introduction to ROC analysisQ29299877
'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic dataQ29784220
Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsisQ30493116
Targeted profiling: quantitative analysis of 1H NMR metabolomics dataQ31047473
Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot studyQ34115285
Pediatric risk of mortality (PRISM) scoreQ34164023
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasmaQ34311681
International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatricsQ34382371
PRISM III: an updated Pediatric Risk of Mortality scoreQ34389009
Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine.Q34605888
Effects of β-hydroxy-β-methylbutyrate treatment in different types of skeletal muscle of intact and septic ratsQ34622685
The clinical evaluation of renal function.Q34934761
In vivo measurement of nitric oxide production in porcine gut, liver and muscle during hyperdynamic endotoxaemiaQ35044830
Lactic acidosis in critical illnessQ35224786
Early Reversal of Pediatric-Neonatal Septic Shock by Community Physicians Is Associated With Improved OutcomeQ35549077
Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosisQ35809534
The influence of developmental age on the early transcriptomic response of children with septic shockQ35876790
Pediatric sepsis and multiorgan dysfunction syndrome: progress and continued challengesQ37882141
Hepatitis C virus infection diagnosis using metabonomics.Q39910291
Mortality associated with multiple organ system failure and sepsis in pediatric intensive care unitQ41461494
Readmission and late mortality after pediatric severe sepsisQ41997960
Role of early fluid resuscitation in pediatric septic shockQ42071311
Paediatric logistic organ dysfunction (PELOD) scoreQ43474590
World Federation of Pediatric Intensive Care and Critical Care Societies: Global Sepsis InitiativeQ43529340
A metabonomic approach to early prognostic evaluation of experimental sepsis by (1)H NMR and pattern recognitionQ46074195
A metabonomic approach to early prognostic evaluation of experimental sepsisQ46601509
Dietary protein or arginine deficiency impairs constitutive and inducible nitric oxide synthesis by young ratsQ48170072
The Pediatric Risk of Mortality III--Acute Physiology Score (PRISM III-APS): a method of assessing physiologic instability for pediatric intensive care unit patients.Q48591607
The epidemiology of severe sepsis in children in the United States.Q50710556
Sequential cardiopulmonary variables of infants and children in septic shock.Q54471771
Orthogonal projections to latent structures (O-PLS)Q56435041
A metabolomic approach for diagnosis of experimental sepsisQ57096834
Protein metabolism in different types of skeletal muscle during early and late sepsis in ratsQ69563690
Distributions of cardiopulmonary variables in pediatric survivors and nonsurvivors of septic shockQ70107552
Hydroxycarboxylic and oxocarboxylic acids in urine: products from branched-chain amino acid degradation and from ketogenesisQ70498319
Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre studyQ73718092
Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in 1H NMR metabonomicsQ79813217
A clinical profile of shock in children in Punjab, IndiaQ80065696
Management of septic shockQ84031865
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectsepsisQ183134
septic shockQ1765564
metabolomicsQ12149006
P304page(s)967-976
P577publication date2013-05-01
P1433published inAmerican Journal of Respiratory and Critical Care MedicineQ4744267
P1476titleMetabolomics as a novel approach for early diagnosis of pediatric septic shock and its mortality
P478volume187

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cites work (P2860)
Q897833511H NMR Based Metabolomics in Human Sepsis and Healthy Serum
Q51815621Application of LC-MS-based metabolomics method in differentiating septic survivors from non-survivors.
Q38204194Applying metabolomics to uncover novel biology in ARDS.
Q55262082Associations of the plasma lipidome with mortality in the acute respiratory distress syndrome: a longitudinal cohort study.
Q38277169Beyond single-nucleotide polymorphisms: genetics, genomics, and other 'omic approaches to acute respiratory distress syndrome
Q58570759Biomarker Phenotype for Early Diagnosis and Triage of Sepsis to the Pediatric Intensive Care Unit
Q38241694Biomarkers of sepsis and their potential value in diagnosis, prognosis and treatment
Q58576665Cohort profile of the Biomarkers of Acute Serious Illness in Children (BASIC) study: a prospective multicentre cohort study in critically ill children
Q34490041Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis
Q35153451Developing a clinically feasible personalized medicine approach to pediatric septic shock
Q36040796Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis.
Q92563885Diagnosis of Bovine Respiratory Disease in feedlot cattle using blood 1H NMR metabolomics
Q36070766Differential expression of the Nrf2-linked genes in pediatric septic shock.
Q34587242Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock
Q34692311Discrimination of sepsis stage metabolic profiles with an LC/MS-MS-based metabolomics approach
Q48249825Emerging Biomarkers of Illness Severity: Urinary Metabolites Associated with Sepsis and Necrotizing Methicillin-Resistant Staphylococcus aureus Pneumonia
Q33584763Extensive alterations of blood metabolites in pediatric cerebral malaria
Q38181708Future clinical applications of genomics for acute respiratory distress syndrome
Q40210673Generalizable Biomarkers in Critical Care: Toward Precision Medicine
Q90683631How could metabolomics change pediatric health?
Q40285651Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP.
Q38697751In Search of a Cure for Sepsis: Taming the Monster in Critical Care Medicine.
Q37226278Increased extracellular heat shock protein 90α in severe sepsis and SIRS associated with multiple organ failure and related to acute inflammatory-metabolic stress response in children
Q35122587Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit
Q62618379Low-Field, Benchtop NMR Spectroscopy as a Potential Tool for Point-of-Care Diagnostics of Metabolic Conditions: Validation, Protocols and Computational Models
Q90558322MetaBridge: An Integrative Multi-Omics Tool for Metabolite-Enzyme Mapping
Q33603672Metabolic Profiling in Patients with Pneumonia on Intensive Care
Q55317384Metabolic Profiling of Amino Acids Associated with Mortality in Patients with Acute Paraquat Poisoning.
Q30654390Metabolic Profiling of Children Undergoing Surgery for Congenital Heart Disease
Q38845332Metabolism, Metabolomics, and Nutritional Support of Patients with Sepsis.
Q45964993Metabolites Associated With Malnutrition in the Intensive Care Unit Are Also Associated With 28-Day Mortality.
Q38657101Metabolome alterations in severe critical illness and vitamin D status.
Q37534631Metabolomic derangements are associated with mortality in critically ill adult patients
Q39386206Metabolomics as a Driver in Advancing Precision Medicine in Sepsis.
Q46104715Metabolomics in the diagnosis of sepsis
Q38551411Metabolomics: Applications and Promise in Mycobacterial Disease.
Q26764983Metabonomics and intensive care
Q37739000Mitochondrial Dysfunction and Immune Cell Metabolism in Sepsis.
Q41715648Monitoring neonatal fungal infection with metabolomics.
Q38202767New diagnostic possibilities in systemic neonatal infections: metabolomics
Q39382251Olfactomedin-4 Is a Candidate Marker for a Pathogenic Neutrophil Subset in Septic Shock
Q38830793Pathogenic, immunologic, and clinical aspects of sepsis - update 2016.
Q90727665Plasma metabolomics and clinical predictors of survival differences in COPD patients
Q33582467Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia
Q60926108Plasma mitochondrial DNA and metabolomic alterations in severe critical illness
Q37625638Post-ICU admission fluid balance and pediatric septic shock outcomes: a risk-stratified analysis.
Q26798603Potential of metabolomics to reveal Burkholderia cepacia complex pathogenesis and antibiotic resistance
Q57174545Precision Medicine for Neonatal Sepsis
Q30903618Preprocessing of NMR metabolomics data
Q35840652Prognosis Biomarkers of Severe Sepsis and Septic Shock by 1H NMR Urine Metabolomics in the Intensive Care Unit.
Q43438772Prognostic markers for pediatric septic shock: which ones, when, and how?
Q30278453Research as a Standard of Care in the PICU.
Q37249625Role of biomarkers in sepsis care.
Q38669414Sepsis reconsidered: Identifying novel metrics for behavioral landscape characterization with a high-performance computing implementation of an agent-based model
Q43141134Sepsis without SIRS is still sepsis.
Q49561103Septic Shock Non-Survivors have Persistently Elevated Acylcarnitines Following Carnitine Supplementation.
Q112281948Systemic inflammation and metabolic disturbances underlie inpatient mortality among ill children with severe malnutrition
Q36181988The pediatric sepsis biomarker risk model: potential implications for sepsis therapy and biology.
Q35120147The temporal version of the pediatric sepsis biomarker risk model
Q37303539Time-resolved metabolomics analysis of individual differences during the early stage of lipopolysaccharide-treated rats
Q102211016Title NMR-based metabolic profiling provides diagnostic and prognostic information in critically ill children with suspected infection
Q38208579Update in pediatric lung disease 2013.
Q35199001Update in sepsis and pulmonary infections 2013.
Q46316924Urinary (1)H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis
Q37736743Urine metabolomics in neonates with late-onset sepsis in a case-control study

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