Sarcoplasmic reticulum Ca2+ leak in heart failure: mere observation or functional relevance?

scientific article published on 21 August 2007

Sarcoplasmic reticulum Ca2+ leak in heart failure: mere observation or functional relevance? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1093/CVR/CVM006
P698PubMed publication ID18006486
P5875ResearchGate publication ID5841500

P50authorChristopher H GeorgeQ42533651
P2093author name stringChristopher H George
P433issue2
P921main subjectheart failureQ181754
P304page(s)302-314
P577publication date2007-08-21
P1433published inCardiovascular ResearchQ4642329
P1476titleSarcoplasmic reticulum Ca2+ leak in heart failure: mere observation or functional relevance?
P478volume77

Reverse relations

cites work (P2860)
Q4806034017β-Estradiol and/or estrogen receptor alpha blocks isoproterenol-induced calcium accumulation and hypertrophy via GSK3β/PP2A/NFAT3/ANP pathway.
Q36130339A mechanistic description of gating of the human cardiac ryanodine receptor in a regulated minimal environment
Q27023389A network-oriented perspective on cardiac calcium signaling
Q40390266Ablation of the cardiac ryanodine receptor phospho-site Ser2808 does not alter the adrenergic response or the progression to heart failure in mice. Elimination of the genetic background as critical variable
Q37162536Adult progenitor cell transplantation influences contractile performance and calcium handling of recipient cardiomyocytes
Q52661325Aerobic interval training reduces inducible ventricular arrhythmias in diabetic mice after myocardial infarction.
Q43279834Alteration of sarcoplasmic reticulum Ca2+ release termination by ryanodine receptor sensitization and in heart failure.
Q41376898Altered Left Ventricular Ion Channel Transcriptome in a High-Fat-Fed Rat Model of Obesity: Insight into Obesity-Induced Arrhythmogenesis
Q39433065An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure
Q58801161Association of cardiac myosin-binding protein-C with the ryanodine receptor channel - putative retrograde regulation?
Q43270475Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug target
Q36421703Bioactive nanoparticles improve calcium handling in failing cardiac myocytes
Q37726503Ca handling during excitation-contraction coupling in heart failure
Q33611715CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors
Q45006857Calcium homeostasis in a local/global whole cell model of permeabilized ventricular myocytes with a Langevin description of stochastic calcium release.
Q42852603Ca²+ spark-dependent and -independent sarcoplasmic reticulum Ca²+ leak in normal and failing rabbit ventricular myocytes
Q50738880Coupling calcium dynamics and mitochondrial bioenergetic: an in silico study to simulate cardiomyocyte dysfunction.
Q91930966Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure
Q35224025Dynamics of calcium sparks and calcium leak in the heart
Q41623018Early and prolonged ECG alterations resembling a myocardial injury after severe amitriptyline poisoning.
Q35239679Electrophysiological and structural remodeling in heart failure modulate arrhythmogenesis. 1D simulation study
Q42577819FRET-based direct detection of dynamic protein kinase A activity on the sarcoplasmic reticulum in cardiomyocytes
Q35556363How does stochastic ryanodine receptor-mediated Ca leak fail to initiate a Ca spark?
Q36364300In search of new therapeutic targets and strategies for heart failure: recent advances in basic science
Q43245413Increased Ca(2+) leak and spatiotemporal coherence of Ca(2+) release in cardiomyocytes during beta-adrenergic stimulation.
Q38021673Inherited calcium channelopathies in the pathophysiology of arrhythmias
Q26829681Ion Channels in the Heart
Q24320070Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis
Q39310132Mechanisms of SR calcium release in healthy and failing human hearts
Q34097829MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex
Q64072001Optogenetic stimulation of G-signaling in the heart with high spatio-temporal precision
Q38907804Pleiotropic mechanisms of action of perhexiline in heart failure
Q50524937Regulation of sarcoplasmic reticulum Ca²⁺ leak by cytosolic Ca²⁺ in rabbit ventricular myocytes.
Q33561848Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease
Q47992873Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts.
Q36068223Ryanodine receptor phosphorylation and heart failure: phasing out S2808 and "criminalizing" S2814.
Q36495468Sarcoplasmic Reticulum Structure and Functional Properties that Promote Long-Lasting Calcium Sparks
Q42087741Termination of cardiac Ca2+ sparks: role of intra-SR [Ca2+], release flux, and intra-SR Ca2+ diffusion
Q42504877The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca2+ leak in ventricular myocytes
Q34986514The relationship between arrhythmogenesis and impaired contractility in heart failure: role of altered ryanodine receptor function.
Q37038915Tricyclic antidepressant amitriptyline alters sarcoplasmic reticulum calcium handling in ventricular myocytes
Q36786515Up-regulation of sarcoplasmic reticulum Ca(2+) uptake leads to cardiac hypertrophy, contractile dysfunction and early mortality in mice deficient in CASQ2.
Q84987760β-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca2+ threshold for Ca2+ wave generation

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