Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry

scientific article published on 27 April 2016

Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00100-16
P932PMC publication ID4907230
P698PubMed publication ID27122575

P2093author name stringWendy Maury
John A Chiorini
Bethany A Rhein
Grace A Schaack
Rachel B Brouillette
P2860cites workTIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserineQ21131381
Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoproteinQ24300740
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria MarburgvirusQ24301153
The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirusQ24305409
Collagen XVI induces expression of MMP9 via modulation of AP-1 transcription factors and facilitates invasion of oral squamous cell carcinomaQ24323337
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infectionQ24329155
C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in transQ24537682
The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entryQ24620686
TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.Q24657708
Tyro3 family-mediated cell entry of Ebola and Marburg virusesQ24670567
Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor familyQ27644081
Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine BindsQ27649330
T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic CellsQ27659032
Identification of a factor that links apoptotic cells to phagocytesQ28217034
TIM-1 induces T cell activation and inhibits the development of peripheral toleranceQ28241921
Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infectionQ28486226
T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinaseQ28755503
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signalsQ79984850
A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTSQ107473800
Ebola Virus Disease: A Review of Its Past and Present.Q30378110
Characterizing functional domains for TIM-mediated enveloped virus entryQ30409350
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosisQ30411888
The phosphatidylserine receptor TIM-4 does not mediate direct signalingQ30447869
T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient miceQ30494990
Identification of Tim4 as a phosphatidylserine receptorQ33303850
Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics studyQ34099067
T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activationQ34144793
Covalent modifications of the ebola virus glycoproteinQ34354004
The Ebola virus matrix protein VP40 selectively induces vesiculation from phosphatidylserine-enriched membranesQ34580401
The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouseQ34734371
Arginyl-glycyl-aspartic acid (RGD): a cell adhesion motifQ34957225
Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alphaQ34976813
TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelopeQ36220496
Phosphatidic acid- and phosphatidylserine-binding proteinsQ36453653
Human macrophage C-type lectin specific for galactose and N-acetylgalactosamine promotes filovirus entryQ36509382
TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent mannerQ36750950
A system for functional analysis of Ebola virus glycoproteinQ36831630
Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry.Q37036794
Variants of the cell recognition site of fibronectin that retain attachment-promoting activityQ37569976
Comprehensive functional analysis of N-linked glycans on Ebola virus GP1.Q37631492
Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4.Q37711963
Role of phosphatidylserine receptors in enveloped virus infectionQ37713918
TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunityQ37763998
Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg virusesQ38258245
Viral apoptotic mimicryQ38520018
Ebola virus entry into host cells: identifying therapeutic strategiesQ38618148
Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways.Q38630528
Tim4- and MerTK-mediated engulfment of apoptotic cells by mouse resident peritoneal macrophages.Q38855733
Two-step engulfment of apoptotic cellsQ39450928
Host Cell Plasma Membrane Phosphatidylserine Regulates the Assembly and Budding of Ebola VirusQ40148983
Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injuryQ40616926
Lipid rafts are enriched in arachidonic acid and plasmenylethanolamine and their composition is independent of caveolin-1 expression: a quantitative electrospray ionization/mass spectrometric analysisQ40752849
Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injuryQ48039370
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.Q51818425
Functional analyses of two cellular binding domains of bovine lactadherinQ73815267
Fibronectin matrix assembly enhances adhesion-dependent cell growthQ77217808
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectOrthoebolavirus zairenseQ10538943
P304page(s)6097-6111
P577publication date2016-04-27
P1433published inJournal of VirologyQ1251128
P1476titleCharacterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry
P478volume90

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cites work (P2860)
Q91650291An exploration of conditions proposed to trigger the Ebola virus glycoprotein for fusion
Q61445598Biomechanical characterization of TIM protein-mediated Ebola virus-host cell adhesion
Q64078182Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors
Q38707770Ebola Virus Disease in Humans: Pathophysiology and Immunity
Q30276544Exosomes in Viral Disease
Q30244058Filovirus proteins for antiviral drug discovery: A structure/function analysis of surface glycoproteins and virus entry
Q39436358Host Factors Involved in Ebola Virus Replication
Q91878844IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infection
Q90729693Lipid Rafts and Pathogens: The Art of Deception and Exploitation
Q40164611Mechanisms of Filovirus Entry.
Q123253382Phosphatidylserine receptors enhance SARS-CoV-2 infection
Q55084398TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus.
Q93046007TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis
Q92001030Tim-4 in Health and Disease: Friend or Foe?

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