Notch signaling pathway is activated in motoneurons of spinal muscular atrophy.

scientific article published on 29 May 2013

Notch signaling pathway is activated in motoneurons of spinal muscular atrophy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS140611424
P8608Fatcat IDrelease_kglaajry5rfitivbvpdreqm5fm
P932PMC publication ID3709740
P698PubMed publication ID23759991
P5875ResearchGate publication ID237199245

P50authorG OlmosQ67934319
Lucia TabaresQ42335167
P2093author name stringJerònia Lladó
Ana Garcera
Andrea Cardona-Rossinyol
Rosa M Soler
Víctor Caraballo-Miralles
Laura Torres-Benito
P2860cites workSpinal muscular atrophyQ21202863
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradationQ24548288
Notch signalling controls pancreatic cell differentiationQ28504686
Identification and characterization of a spinal muscular atrophy-determining geneQ29547495
The canonical Notch signaling pathway: unfolding the activation mechanismQ29547725
Inflammation in ALS and SMA: sorting out the good from the evilQ33664711
Nuclear Notch1 signaling and the regulation of dendritic developmentQ33884395
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.Q34034245
TGFbeta1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiationQ34034940
SMN requirement for synaptic vesicle, active zone and microtubule postnatal organization in motor nerve terminalsQ34056100
Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.Q50592601
Notch signalling and the control of cell fate choices in vertebrates.Q52180338
Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing.Q52192652
Smn deficiency causes neuritogenesis and neurogenesis defects in the retinal neurons of a mouse model of spinal muscular atrophy.Q54409832
SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA.Q54540847
Defective Neuromuscular Junction Organization and Postnatal Myogenesis in Mice With Severe Spinal Muscular AtrophyQ58794833
A new model to study spinal muscular atrophy: Neurite degeneration and cell death is counteracted by BCL-XL Overexpression in motoneuronsQ62382338
Abnormal motoneuron migration, differentiation, and axon outgrowth in spinal muscular atrophyQ80187331
An autopsy case of spinal muscular atrophy type III (Kugelberg-Welander disease)Q81077837
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosisQ81078641
Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrityQ81303651
SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMNQ81385781
Ligand-dependent Notch signaling in vascular formationQ34259558
Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.Q34666063
More complicated than it looks: assembly of Notch pathway transcription complexesQ34817647
Not(ch) just development: Notch signalling in the adult brainQ35175155
Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.Q35567371
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunctionQ35657354
Notch: from neural development to neurological disordersQ35981799
Notch signalling in vertebrate neural developmentQ36374960
Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophyQ36379979
Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryosQ36578997
The many facets of Notch ligandsQ37256458
Embryonic motor axon development in the severe SMA mouseQ37294791
Notch: a new player in MS mechanismsQ37596103
Notch activity in the nervous system: to switch or not switch?Q37607400
Transforming growth factor-β signaling in motor neuron diseasesQ37824332
Notch in the vertebrate nervous system: an old dog with new tricksQ37850550
Notch signaling modulates the activation of microglial cellsQ40092415
Correlation between severity and SMN protein level in spinal muscular atrophyQ41102726
The neurobiology of childhood spinal muscular atrophy.Q41489423
Notch signaling is required for activity-dependent synaptic plasticity at the Drosophila neuromuscular junction.Q41855833
Novel effectors of directed and Ngn3-mediated differentiation of mouse embryonic stem cells into endocrine pancreas progenitorsQ42520128
Endothelial progenitor cells promote astrogliosis following spinal cord injury through Jagged1-dependent Notch signalingQ42797685
Consequences of Notch-mediated induction of Jagged1.Q42828884
Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus.Q43126830
Neuropathological analysis in spinal muscular atrophy type II.Q44536467
Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury.Q45856412
Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch.Q45940869
Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants.Q45992277
Jagged1 regulates the activation of astrocytes via modulation of NFkappaB and JAK/STAT/SOCS pathwaysQ47762950
Neonatal spinal muscular atrophy with multiple contractures, bone fractures, respiratory insufficiency and 5q13 deletion.Q48018905
Notch1 inhibits neurite outgrowth in postmitotic primary neuronsQ48125597
Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer diseaseQ48404402
Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.Q48551433
Notch and NGF/p75NTR control dendrite morphology and the balance of excitatory/inhibitory synaptic input to hippocampal neurones through Neurogenin 3.Q48617715
Notch-1 immunoexpression is increased in Alzheimer's and Pick's diseaseQ48652919
Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP.Q48800271
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectspinal muscular atrophyQ580290
P304page(s)11424-11437
P577publication date2013-05-29
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleNotch signaling pathway is activated in motoneurons of spinal muscular atrophy
P478volume14

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cites work (P2860)
Q38715282Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy
Q89743182Dominant mutations of the Notch ligand Jagged1 cause peripheral neuropathy
Q64059452Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems
Q34142599Transcriptome profiling of spinal muscular atrophy motor neurons derived from mouse embryonic stem cells

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