scholarly article | Q13442814 |
P50 | author | Guy M. Lenk | Q37604576 |
P2093 | author name string | Peter Shrager | |
Miriam H Meisler | |||
Cole J Ferguson | |||
Roman J Giger | |||
Jesse J Winters | |||
Vessela I Giger-Mateeva | |||
P2860 | cites work | Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination | Q24310284 |
Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions | Q24316000 | ||
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse | Q24318746 | ||
Astrocytes promote myelination in response to electrical impulses | Q24547572 | ||
ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder | Q24621406 | ||
The lysosomal sialic acid transporter sialin is required for normal CNS myelination | Q24648839 | ||
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination | Q24657511 | ||
Phosphoinositides in cell regulation and membrane dynamics | Q27861051 | ||
Vacuole Size Control: Regulation of PtdIns(3,5)P2Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P2-specific Phosphatase | Q27933521 | ||
Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J | Q28478398 | ||
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture | Q28506321 | ||
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J | Q28511673 | ||
Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition | Q28567486 | ||
Paranodin, a glycoprotein of neuronal paranodal membranes | Q28572513 | ||
LINGO-1 negatively regulates myelination by oligodendrocytes | Q28588853 | ||
The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein | Q28771372 | ||
A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities | Q49049294 | ||
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. | Q52170285 | ||
Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS. | Q52174918 | ||
The relationship between internodal length and fibre diameter in the spinal cord of the cat. | Q52436528 | ||
A program for simulation of nerve equations with branching geometries. | Q52538070 | ||
Astrocytes, but not olfactory ensheathing cells or Schwann cells, promote myelination of CNS axons in vitro. | Q53496575 | ||
Changing phosphoinositides "on the fly": how trafficking vesicles avoid an identity crisis. | Q54724417 | ||
A computational test of the requirements for conduction in demyelinated axons | Q84063207 | ||
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome | Q29543488 | ||
Oligodendrocytes: biology and pathology | Q30051584 | ||
Induction of myelination in the central nervous system by electrical activity. | Q30453890 | ||
Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule | Q30454391 | ||
Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration | Q30489465 | ||
Update on genetic disorders affecting white matter | Q30628463 | ||
Animal models for autoimmune demyelinating disorders of the nervous system | Q33826625 | ||
Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P₂ phosphatase FIG4. | Q34195421 | ||
Cell death and control of cell survival in the oligodendrocyte lineage | Q34460930 | ||
The molecular basis of mucolipidosis type IV. | Q34748134 | ||
Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex. | Q34848711 | ||
Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS. | Q34913669 | ||
Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function | Q34959368 | ||
Astrocytic tissue inhibitor of metalloproteinase-1 (TIMP-1) promotes oligodendrocyte differentiation and enhances CNS myelination | Q34960361 | ||
Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2. | Q35005794 | ||
Differentiation and death of premyelinating oligodendrocytes in developing rodent brain | Q36273807 | ||
Control of local protein synthesis and initial events in myelination by action potentials | Q36350920 | ||
Optical measurement of conduction in single demyelinated axons | Q36410502 | ||
Autosomal-recessive forms of demyelinating Charcot-Marie-Tooth disease | Q36507147 | ||
Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system | Q37116136 | ||
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain | Q37179554 | ||
Integrin-mediated axoglial interactions initiate myelination in the central nervous system | Q37263985 | ||
Disruption of Nectin-like 1 cell adhesion molecule leads to delayed axonal myelination in the CNS. | Q37309625 | ||
Endothelin-1 regulates oligodendrocyte development | Q37368275 | ||
Phosphatidylinositol metabolism and membrane fusion | Q37386315 | ||
Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells | Q37470965 | ||
Neurodegeneration in Niemann-Pick Type C disease and Huntington's disease: impact of defects in membrane trafficking | Q37550648 | ||
The complex world of oligodendroglial differentiation inhibitors | Q37869047 | ||
Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2. | Q37898748 | ||
Control of oligodendrocyte number in the developing rat optic nerve | Q40753787 | ||
Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. | Q41712768 | ||
Anatomy of rat semaphorin III/collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis | Q42526905 | ||
Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent | Q42677331 | ||
Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter control | Q46168479 | ||
Notch receptor activation inhibits oligodendrocyte differentiation | Q47713081 | ||
Axonal coding of action potentials in demyelinated nerve fibers | Q48233190 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 48 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | congenital disorder | Q727096 |
P304 | page(s) | 17736-17751 | |
P577 | publication date | 2011-11-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4 | |
P478 | volume | 31 |
Q44216960 | ALS-associated protein FIG4 is localized in Pick and Lewy bodies, and also neuronal nuclear inclusions, in polyglutamine and intranuclear inclusion body diseases. |
Q91444964 | Cerebral hypomyelination associated with biallelic variants of FIG4 |
Q36592491 | Fig4 deficiency: a newly emerged lysosomal storage disorder? |
Q89452029 | Gene therapies for axonal neuropathies: Available strategies, successes to date, and what to target next |
Q91194191 | Identification of CR43467 encoding a long non-coding RNA as a novel genetic interactant with dFIG4, a CMT-causing gene |
Q28571064 | LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin. |
Q47130977 | LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair. |
Q42133744 | Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice |
Q33764669 | Mouse models of PI(3,5)P2 deficiency with impaired lysosome function. |
Q37351972 | Murine Fig4 is dispensable for muscle development but required for muscle function |
Q30523191 | Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. |
Q34672075 | Npc1 acting in neurons and glia is essential for the formation and maintenance of CNS myelin |
Q36957125 | PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms |
Q26823539 | Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance |
Q27012953 | Phosphoinositides: tiny lipids with giant impact on cell regulation |
Q50488733 | Preferential conduction block of myelinated axons by nitric oxide. |
Q52311182 | Protective Role of the Lipid Phosphatase Fig4 in the Adult Nervous System. |
Q30696655 | Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene |
Q28508873 | Ten-m3 is required for the development of topography in the ipsilateral retinocollicular pathway |
Q36031613 | Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis |
Q50432878 | The DYT6 Dystonia Protein THAP1 Regulates Myelination within the Oligodendrocyte Lineage. |
Q90957586 | The K2P -channel TASK1 affects Oligodendroglial differentiation but not myelin restoration |
Q33649917 | The Sac domain-containing phosphoinositide phosphatases: structure, function, and disease |
Q38634867 | The extended human PTPome: a growing tyrosine phosphatase family |
Q30362381 | Transient auditory nerve demyelination as a new mechanism for hidden hearing loss. |
Q36817367 | Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase |