System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties

scientific article published on August 2008

System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CHEMBIOL.2008.07.006
P932PMC publication ID2606095
P698PubMed publication ID18721752
P5875ResearchGate publication ID23188638

P2093author name stringWilliam S Lane
John Rush
Gavin MacBeath
Bogdan A Budnik
Alexis Kaushansky
Andrew Gordus
P2860cites workA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisQ22253346
A quantitative protein interaction network for the ErbB receptors using protein microarraysQ24293746
Acetylation-dependent signal transduction for type I interferon receptorQ24296831
The role of STATs in apoptosisQ24301148
Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3Q24309266
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperoneQ24313108
HER4-mediated biological and biochemical properties in NIH 3T3 cells. Evidence for HER1-HER4 heterodimersQ24336345
Expression of HER3, HER4 and their ligand heregulin-4 is associated with better survival in bladder cancer patientsQ24645597
Outcome and human epidermal growth factor receptor (HER) 1-4 status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labellingQ24794988
Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphataseQ27729401
Structure and ligand recognition of the phosphotyrosine binding domain of ShcQ27732196
Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domainQ27732609
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneQ27860693
SH2 domains recognize specific phosphopeptide sequencesQ27860748
Untangling the ErbB signalling networkQ27860884
ErbB-4: mechanism of action and biologyQ28185260
gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinaseQ28202328
Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometryQ28211506
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomasQ28287906
The involvement of ErbB4 with schizophrenia: association and expression studiesQ28290653
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactionsQ28609149
The structural basis for 14-3-3:phosphopeptide binding specificityQ29547190
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and VavQ29615971
The Clinical Significance of Epidermal Growth Factor Receptor (EGF-R) in Human Breast Cancer: A Review on 5232 Patients*Q33188817
A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R.Q33610352
ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease.Q34153957
An alternative to SH2 domains for binding tyrosine-phosphorylated proteinsQ34292972
Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptorQ34381905
SH2 and PTB domains in tyrosine kinase signalingQ35178872
STAT proteins: From normal control of cellular events to tumorigenesisQ35540165
STAT-1: a novel regulator of apoptosisQ35641356
Signal transduction and oncogenesis by ErbB/HER receptorsQ35669114
The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patientsQ36614287
STAT1 as a key modulator of cell deathQ36644901
JAK-STAT signaling: from interferons to cytokinesQ36821751
The epidermal growth factor family has a dual role in deciding the fate of cancer cells.Q40209050
Interferon signaling is dependent on specific tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cellsQ40772032
The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2.Q40808240
Signal transduction by epidermal growth factor and heregulin via the kinase-deficient ErbB3 proteinQ42159151
Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma.Q44314802
Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breastQ46402523
Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophreniaQ46775363
STATs as activators of apoptosisQ47721568
Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis.Q52183100
Circumventing the problems caused by protein diversity in microarrays: implications for protein interaction networks.Q53011764
SH-PTP2/Syp SH2 domain binding specificity is defined by direct interactions with platelet-derived growth factor beta-receptor, epidermal growth factor receptor, and insulin receptor substrate-1-derived phosphopeptidesQ72332095
Binding specificities and affinities of egf domains for ErbB receptorsQ77360929
P433issue8
P921main subjectphosphorylationQ242736
P304page(s)808-817
P577publication date2008-08-01
P1433published inChemistry and BiologyQ15758410
P1476titleSystem-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties
P478volume15

Reverse relations

cites work (P2860)
Q34511038AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity
Q37598176Applications of protein biochips in biomedical and biotechnological research
Q50298005Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers
Q50298043Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers
Q35026889Carboxyl-group footprinting maps the dimerization interface and phosphorylation-induced conformational changes of a membrane-associated tyrosine kinase.
Q92352874Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases
Q34413697Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors
Q42265191Crosstalk and competition in signaling networks
Q90252710Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites
Q41682816Direct coupling of the HER4 intracellular domain (4ICD) and STAT5A signaling is required to induce mammary epithelial cell differentiation
Q38931276Discovering Protein-Protein Interactions Using Nucleic Acid Programmable Protein Arrays.
Q36067899ERBB4 is over-expressed in human colon cancer and enhances cellular transformation
Q47974787ErbB Receptors and Cancer
Q37734240ErbB receptors and their growth factor ligands in pediatric intestinal inflammation
Q83601013ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors
Q93370017ErbB4 point mutation in CU3 inbred rats affects gonadotropin-releasing-hormone neuronal function via compromised neuregulin-stimulated prostaglandin E2 release from astrocytes
Q39687374ErbB4 promotes cyclooxygenase-2 expression and cell survival in colon epithelial cells
Q37149729Functional selectivity of EGF family peptide growth factors: implications for cancer
Q33747967Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system
Q26859524Identification of Posttranslational Modification-Dependent Protein Interactions Using Yeast Surface Displayed Human Proteome Libraries
Q33706791Interactive proteomics research technologies: recent applications and advances
Q38010411Interactome mapping for analysis of complex phenotypes: insights from benchmarking binary interaction assays
Q57105786Mechanisms Underlying the Action and Synergism of Trastuzumab and Pertuzumab in Targeting HER2-Positive Breast Cancer
Q30458926Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy
Q37722550Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.
Q36408020Neuregulin-4 is a survival factor for colon epithelial cells both in culture and in vivo
Q36804007Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling
Q36427519Phosphotyrosine recognition domains: the typical, the atypical and the versatile
Q28284451Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected
Q35109872Protein microarrays: novel developments and applications
Q36959749Quantifying oncogenic phosphotyrosine signaling networks through systems biology
Q34895651Quantifying protein-protein interactions in high throughput using protein domain microarrays
Q37330722Quantitative modeling perspectives on the ErbB system of cell regulatory processes
Q36010566Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors
Q50298039SHC1 binds P-ERBB4 isoform dimers
Q50297990SHC1 binds phosphorylated ERBB2 heterodimers
Q45318103Signaling by ERBB4
Q27682496Superbinder SH2 domains act as antagonists of cell signaling
Q35159615TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival
Q39551398Tensin2 is a novel mediator in thrombopoietin (TPO)-induced cellular proliferation by promoting Akt signaling
Q36468741The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis.
Q37650953The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist.
Q34308157The application of modular protein domains in proteomics
Q50297989Trans-autophosphorylation of ERBB2 heterodimers
Q50298036Trans-autophosphorylation of ERBB4 homodimers
Q26801529Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association
Q27323917Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements
Q92153694Use of QSAR Global Models and Molecular Docking for Developing New Inhibitors of c-src Tyrosine Kinase

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