Wiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities

scientific article published on 25 August 2015

Wiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/19491034.2015.1086051
P932PMC publication ID4915506
P698PubMed publication ID26305109
P5875ResearchGate publication ID281303815

P50authorJeffrey M VerboonQ57055577
Bina SugumarQ95975832
P2093author name stringSusan M Parkhurst
P2860cites workA novel cofactor for p300 that regulates the p53 responseQ22010639
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome proteinQ22253357
The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migrationQ24298177
WASH and the Arp2/3 complex regulate endosome shape and traffickingQ24300504
Human subtelomeric WASH genes encode a new subclass of the WASP familyQ24304930
Structure and control of the actin regulatory WAVE complexQ24308919
WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexesQ24314791
A FAM21-containing WASH complex regulates retromer-dependent sortingQ24318406
The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complexQ24318446
Mdm2 targets the p53 transcription cofactor JMY for degradationQ24337019
WASP family proteins: their evolution and its physiological implications.Q24632578
Cytoskeletal dynamics: a view from the membraneQ26829338
Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesQ27009455
Role of the WASP and WAVE family proteins in breast cancer invasion and metastasisQ28082304
N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways.Q53353944
A novel role of the actin-nucleating Arp2/3 complex in the regulation of RNA polymerase II-dependent transcriptionQ79551272
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partnersQ83968708
Actin-dependent intranuclear repositioning of an active gene locus in vivo.Q36274498
Nuclear actin and myosins at a glanceQ36497514
Visualization of actin filaments and monomers in somatic cell nucleiQ36717398
Evidence for monomeric actin function in INO80 chromatin remodelingQ36745311
Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal developmentQ37298089
A transcription co-factor integrates cell adhesion and motility with the p53 response.Q37446442
Mechanisms of nuclear actin in chromatin-remodeling complexes.Q37716257
WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyondQ37796281
Nuclear actin and myosins: life without filamentsQ37952090
New insights into the regulation and cellular functions of the ARP2/3 complexQ38065085
Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteinsQ38070409
Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression.Q38193984
TRF2 associates with DREF and directs promoter-selective gene expression in DrosophilaQ38360296
Cofilin nuclear-cytoplasmic shuttling affects cofilin-actin rod formation during stressQ39343125
Nuclear actin levels as an important transcriptional switchQ39997341
The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongationQ42138179
An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.Q42797525
Steady-state nuclear actin levels are determined by export competent actin poolQ42818284
Nuclear actin network assembly by formins regulates the SRF coactivator MAL.Q42823636
Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90.Q44519371
Differential regulation of WASP and N-WASP by Cdc42, Rac1, Nck, and PI(4,5)P2.Q46240470
Focal adhesion kinase regulation of N-WASP subcellular localization and functionQ28118737
The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organizationQ28198756
PSF and p54(nrb)/NonO--multi-functional nuclear proteinsQ28213410
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and NckQ28218186
FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formationQ28236387
The WASP-WAVE protein network: connecting the membrane to the cytoskeletonQ29616493
Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matricesQ30480500
Wash functions downstream of Rho and links linear and branched actin nucleation factorsQ30489687
Wash functions downstream of Rho1 GTPase in a subset of Drosophila immune cell developmental migrations.Q30651019
Clinical course of patients with WASP gene mutationsQ33349914
Mutations of the Wiskott-Aldrich Syndrome Protein (WASP): hotspots, effect on transcription, and translation and phenotype/genotype correlationQ33361928
Genetic characteristics of eighty-seven patients with the Wiskott-Aldrich syndrome.Q33393417
Disruption of hSWI/SNF complexes in T cells by WAS mutations distinguishes X-linked thrombocytopenia from Wiskott-Aldrich syndromeQ33417841
X-linked thrombocytopenia and Wiskott-Aldrich syndrome are allelic diseases with mutations in the WASP geneQ33489988
Nuclear functions of actinQ33752191
Nuclear role of WASp in gene transcription is uncoupled from its ARP2/3-dependent cytoplasmic role in actin polymerization.Q34063501
Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndromeQ34143892
Evolution of the eukaryotic ARP2/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAMLQ34153579
Actin in the nucleus: what form and what for?Q34165742
Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytesQ34181902
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent mannerQ34230535
Diffusible and bound actin in nuclei of xenopus laevis oocytesQ34236712
Active maintenance of nuclear actin by importin 9 supports transcriptionQ34253452
Nuclear actin and myosin I are required for RNA polymerase I transcription.Q34370248
A role for beta-actin in RNA polymerase III transcriptionQ34372693
Nucleoplasmic beta-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations.Q34494242
Long-range directional movement of an interphase chromosome siteQ34516449
WASp in immune-system organization and functionQ34810230
G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb).Q34869767
Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cellsQ34961689
An actin-ribonucleoprotein interaction is involved in transcription by RNA polymerase II.Q35143311
Wash interacts with lamin and affects global nuclear organizationQ35196285
Developmental expression of Drosophila Wiskott-Aldrich Syndrome family proteinsQ35785194
Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY.Q35790908
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P433issue5
P921main subjectWiskott-Aldrich syndromeQ953638
P304page(s)349-359
P577publication date2015-08-25
P1433published inNucleusQ26842588
P1476titleWiskott-Aldrich syndrome proteins in the nucleus: aWASH with possibilities
P478volume6

Reverse relations

cites work (P2860)
Q38723568Actin, actin-binding proteins, and actin-related proteins in the nucleus
Q36413725Cellular functions of WASP family proteins at a glance
Q47415009Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B.
Q59066270Nuclear F-actin and myosins drive relocalization of heterochromatic breaks
Q93087437Nuclear actin filaments in DNA repair dynamics
Q52352298Wash exhibits context-dependent phenotypes and, along with the WASH regulatory complex, regulates Drosophila oogenesis.

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