The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells

scientific article published on 17 September 2008

The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BCP.2008.09.011
P932PMC publication ID2610527
P698PubMed publication ID18840413

P2093author name stringMary Pat Moyer
Magdalena L Circu
Tak Yee Aw
Sarah Stringer
Carol Ann Rhoads
P2860cites workImmunohistology of the Antigenic Pattern of a Continuous Cell Line From a Human Colon TumorQ67252490
Protection by glutathione and other thiol compounds against the loss of protein thiols and tocopherol homologs during microsomal lipid peroxidationQ67589655
High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfidesQ71323735
Identification and characterization of high and low affinity transport systems for reduced glutathione in liver cell canalicular membranesQ72108003
Nuclear translocation of a leukocyte elastase Inhibitor/Elastase complex during staurosporine-induced apoptosis: role in the generation of nuclear L-DNase II activityQ73329788
Suppression of apoptosis is responsible for increased thickness of intestinal mucosa in streptozotocin-induced diabetic ratsQ73568261
Lipid hydroperoxide-induced apoptosis in human colonic CaCo-2 cells is associated with an early loss of cellular redox balanceQ74121571
Oxidation of the glutathione/glutathione disulfide redox state is induced by cysteine deficiency in human colon carcinoma HT29 cellsQ74578869
Caspase and proteasome activity during staurosporin-induced apoptosis in lens epithelial cells.Q33180871
Molecular and cellular responses to oxidative stress and changes in oxidation-reduction imbalance in the intestineQ33740097
Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinasesQ34675057
Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporineQ35691202
Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formationQ36496301
Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosisQ36509311
Generating disulfides with the Quiescin-sulfhydryl oxidasesQ36642894
Glutathione export during apoptosis requires functional multidrug resistance-associated proteinsQ40156381
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosisQ40392550
manipulation of cell death — the development of novel strategies for the treatment of gastrointestinal diseaseQ40470965
A novel inhibitor that protects apoptotic DNA fragmentation catalyzed by DNase gammaQ40489839
Exogenous cysteine and cystine promote cell proliferation in CaCo-2 cellsQ40738385
Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologistQ40945812
Cl- transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon.Q41005959
Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinaseQ42216028
Differential susceptibility of naive and differentiated PC-12 cells to methylglyoxal-induced apoptosis: influence of cellular redoxQ42484415
NCM460, a normal human colon mucosal epithelial cell lineQ42812955
The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survivalQ42828483
Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potentialQ43722380
Induction of mild intracellular redox imbalance inhibits proliferation of CaCo-2 cellsQ43771261
Mechanism of staurosporine-induced apoptosis in murine hepatocytesQ43964292
Phosphatidylserine peroxidation/externalization during staurosporine-induced apoptosis in HL-60 cellsQ44075460
Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alphaQ44189931
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.Q44671564
Decreased susceptibility of differentiated PC12 cells to oxidative challenge: relationship to cellular redox and expression of apoptotic protease activator factor-1.Q46475085
The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax.Q46553824
Programmed cell death in rat intestine: effect of feeding and fasting.Q51550761
SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis.Q53610008
Interaction of gamma-glutamyl transpeptidase with acivicin.Q53796726
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)76-85
P577publication date2008-09-17
P1433published inBiochemical PharmacologyQ864229
P1476titleThe role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells
P478volume77

Reverse relations

cites work (P2860)
Q39549213Aged red garlic extract reduces cigarette smoke extract-induced cell death in human bronchial smooth muscle cells by increasing intracellular glutathione levels
Q37574928Apoptosis and glutathione: beyond an antioxidant.
Q39775968CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules.
Q37368883Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells
Q38974021Glutathione administration reduces mitochondrial damage and shifts cell death from necrosis to apoptosis in ageing diabetic mice hearts during exercise
Q36221338Glutathione and modulation of cell apoptosis
Q24643554Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis
Q37663725Glutathione depletion regulates both extrinsic and intrinsic apoptotic signaling cascades independent from multidrug resistance protein 1.
Q36326528Glutathione efflux and cell death
Q37023604Loss of Mrp1 Potentiates Doxorubicin-Induced Cytotoxicity in Neonatal Mouse Cardiomyocytes and Cardiac Fibroblasts
Q38093018Mechanisms involved in the pro-apoptotic effect of melatonin in cancer cells
Q38875536Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome
Q28388476Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis
Q28393669Reactive oxygen species, cellular redox systems, and apoptosis
Q35534376Redox biology of the intestine
Q42735154Rotenone enhances the antifungal properties of staurosporine
Q33993016S-Glutathionyl quantification in the attomole range using glutaredoxin-3-catalyzed cysteine derivatization and capillary gel electrophoresis with laser-induced fluorescence detection
Q53120803S-Glutathionylation of Keap1: a new role for glutathione S-transferase pi in neuronal protection.
Q34999641The Cystine/Glutamate Antiporter Regulates Dendritic Cell Differentiation and Antigen Presentation
Q34117587The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism
Q91690576Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy
Q34576857Volume-sensitive anion channels mediate osmosensitive glutathione release from rat thymocytes