Protein kinase C signaling in the hypothalamic arcuate nucleus regulates sexual receptivity in female rats.

scientific article published on 24 July 2008

Protein kinase C signaling in the hypothalamic arcuate nucleus regulates sexual receptivity in female rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/EN.2008-0847
P932PMC publication ID2613064
P698PubMed publication ID18653714
P5875ResearchGate publication ID51427131

P50authorAmy ChristensenQ57001851
P2093author name stringPhoebe Dewing
Galyna Bondar
Paul Micevych
P2860cites workMolecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cellsQ24322070
The extended protein kinase C superfamilyQ24530820
Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathwayQ28572267
Functional interactions between estrogen and insulin-like growth factor-I in the regulation of alpha 1B-adrenoceptors and female reproductive functionQ28579648
Estrogen-induced alteration of mu-opioid receptor immunoreactivity in the medial preoptic nucleus and medial amygdala.Q32065361
Membrane estrogen receptor-alpha interactions with metabotropic glutamate receptor 1a modulate female sexual receptivity in ratsQ33996298
Sex and estrogenic effects on coexpression of mRNAs in single ventromedial hypothalamic neuronsQ34063694
Mapping of neural and signal transduction pathways for lordosis in the search for estrogen actions on the central nervous systemQ34473184
Estrogen modulation of K(+) channel activity in hypothalamic neurons involved in the control of the reproductive axisQ34605432
Rapid effects of estrogen on G protein-coupled receptor activation of potassium channels in the central nervous system (CNS).Q35089993
Visualizing activation of opioid circuits by internalization of G protein-coupled receptorsQ35141408
Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcriptionQ35723711
Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cellsQ36016357
Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analysing neuroprotective mechanisms.Q36092313
Integration of steroid hormone initiated membrane action to genomic function in the brain.Q36111306
Membrane-initiated signaling of estrogen in the brainQ36796994
The membrane actions of estrogens can potentiate their lordosis behavior-facilitating genomic actionsQ37485100
Estrogen induces phosphorylation of cyclic AMP response element binding (pCREB) in primary hippocampal cells in a time-dependent mannerQ38450504
Chronic-alcohol exposure alters IGF1 signaling in H9c2 cells via changes in PKC deltaQ40204304
Estradiol induces PKA activation through the putative membrane receptor in the living hippocampal neuronQ40358712
Roles of second-messenger systems and neuronal activity in the regulation of lordosis by neurotransmitters, neuropeptides, and estrogen: a reviewQ40624979
Estrogen activation of cyclic adenosine 5'-monophosphate response element-mediated transcription requires the extracellularly regulated kinase/mitogen-activated protein kinase pathwayQ40670698
Ligand-independent activation of pituitary ER: dependence on PKA-stimulated pathwaysQ40791713
Protein kinase C isoforms in pituitary cells displaying differential sensitivity to phorbol esterQ40895556
Transcriptional effects of estrogen on neuronal neurotensin gene expression involve cAMP/protein kinase A-dependent signaling mechanisms.Q41014884
Protein kinase C isozymes and substratesQ41099683
Rapid estrogenic regulation of extracellular signal- regulated kinase 1/2 signaling in cerebellar granule cells involves a G protein- and protein kinase A-dependent mechanism and intracellular activation of protein phosphatase 2A.Q42483185
Modulation of cytosolic protein kinase C and calcium ion activity by steroid hormones in rat distal colonQ42517086
17 beta-estradiol-BSA conjugates and 17 beta-estradiol regulate growth plate chondrocytes by common membrane associated mechanisms involving PKC dependent and independent signal transductionQ43545781
Protein kinase C isoenzyme: selective expression pattern of protein kinase C-θ during mouse developmentQ43596623
Progesterone blockade of estrogen activation of mu-opioid receptors regulates reproductive behavior.Q43683728
AMPA receptor function is altered in GLUR2-deficient miceQ43772805
ERs associate with and regulate the production of caveolin: implications for signaling and cellular actionsQ43843581
Estradiol inhibits atp-induced intracellular calcium concentration increase in dorsal root ganglia neuronsQ43858390
Mechanism of the rapid effect of 17 beta-estradiol on medial amygdala neuronsQ44269502
Influence of opioid peptides on the priming action of estrogen on lordosis in ovariectomized ratsQ44343122
Estrogen-induced mu-opioid receptor internalization in the medial preoptic nucleus is mediated via neuropeptide Y-Y1 receptor activation in the arcuate nucleus of female rats.Q44344359
Sexual receptivity is reduced in the female mu-opioid receptor knockout mouseQ44350487
Nongenomic mechanism of glucocorticoid inhibition of bradykinin-induced calcium influx in PC12 cells: possible involvement of protein kinase C.Q44371472
Estrogen levels regulate the subcellular distribution of phosphorylated Akt in hippocampal CA1 dendrites.Q44376595
Estrogen-dependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membrane-mediated and inhibited by tamoxifenQ44405090
Participation of growth factor signal transduction pathways in estradiol facilitation of female reproductive behaviorQ44559274
Major sex differences in non-genomic estrogen actions on intracellular signaling in mouse brain in vivo.Q45303845
A conserved mechanism for steroid receptor translocation to the plasma membraneQ46081038
Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathwaysQ46151469
17 beta-estradiol depolarization of hypothalamic neurons is mediated by cyclic AMP.Q46364889
17-Beta estradiol rapidly enhances extracellular signal-regulated kinase 2 phosphorylation in the rat brainQ46490181
Estradiol activates group I and II metabotropic glutamate receptor signaling, leading to opposing influences on cAMP response element-binding protein.Q46497183
Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cellsQ46944972
Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in mouse brain.Q47194082
Estradiol elevates protein kinase C catalytic activity in the preoptic area of female ratsQ47914452
Estrogen-induced activation of mitogen-activated protein kinase in cerebral cortical explants: convergence of estrogen and neurotrophin signaling pathways.Q48287209
Estradiol stimulates progesterone synthesis in hypothalamic astrocyte cultures.Q48374570
Localization of mRNAs for novel, atypical as well as conventional protein kinase C (PKC) isoforms in the brain of developing and mature ratsQ48970068
Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor.Q51044296
A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer.Q54558859
Phorbol esters and forskolin infused into midbrain central gray facilitate lordosisQ69444512
Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brainQ71033349
17 beta-Estradiol potentiates kainate-induced currents via activation of the cAMP cascadeQ71106313
Activation of protein kinase C in the hypothalamic ventromedial nucleus or the midbrain central gray facilitates lordosisQ72407005
Estrogenic stimulation of neurite growth in midbrain dopaminergic neurons depends on cAMP/protein kinase A signallingQ73408314
Factors elevating cAMP attenuate the effects of 8-OH-DPAT on lordosis behaviorQ73954837
Caveolin proteins are essential for distinct effects of membrane estrogen receptors in neuronsQ81250939
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)5934-5942
P577publication date2008-07-24
P1433published inEndocrinologyQ3054009
P1476titleProtein kinase C signaling in the hypothalamic arcuate nucleus regulates sexual receptivity in female rats
P478volume149

Reverse relations

cites work (P2860)
Q37734708A Novel Membrane Estrogen Receptor Activated by STX Induces Female Sexual Receptivity through an Interaction with mGluR1a.
Q37444952Actions of Steroids: New Neurotransmitters
Q36114029CAV1 siRNA reduces membrane estrogen receptor-α levels and attenuates sexual receptivity
Q26853424Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity
Q36269934Developmental time course and effects of immunostressors that alter hormone-responsive behavior on microglia in the peripubertal and adult female mouse brain.
Q37547760Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus
Q52721019Diverse actions of estradiol on anorexigenic and orexigenic hypothalamic arcuate neurons.
Q37034911Doing protein kinase C: membrane estrogen receptor signaling in a neural circuit
Q36848198Dopamine agonist signalling in the hypothalamus of female rats is independent of calcium-dependent kinases
Q27022948Estradiol Membrane-Initiated Signaling and Female Reproduction
Q45969727Estradiol Membrane-Initiated Signaling in the Brain Mediates Reproduction.
Q37100107Estradiol Rapidly Attenuates ORL-1 Receptor-Mediated Inhibition of Proopiomelanocortin Neurons via Gq-Coupled, Membrane-Initiated Signaling
Q37110920Estradiol dose-dependent regulation of membrane estrogen receptor-α, metabotropic glutamate receptor-1a, and their complexes in the arcuate nucleus of the hypothalamus in female rats.
Q33901187Estradiol modulates translocator protein (TSPO) and steroid acute regulatory protein (StAR) via protein kinase A (PKA) signaling in hypothalamic astrocytes
Q34222438Estradiol negatively modulates the pleiotropic actions of orphanin FQ/nociceptin at proopiomelanocortin synapses.
Q34628590Estradiol rapidly regulates membrane estrogen receptor alpha levels in hypothalamic neurons
Q36392903Estradiol signaling in the regulation of reproduction and energy balance
Q34476359Estradiol upregulates progesterone receptor and orphanin FQ colocalization in arcuate nucleus neurons and opioid receptor-like receptor-1 expression in proopiomelanocortin neurons that project to the medial preoptic nucleus in the female rat.
Q33718254Estradiol-induced estrogen receptor-alpha trafficking
Q33928066Estrogen actions on neuroendocrine glia
Q47971704Estrogen receptor α and β are involved in the activation of lordosis behavior in estradiol-primed rats
Q34757712Estrogen signaling in hypothalamic circuits controling reproduction
Q34712589Evidence for gating roles of protein kinase A and protein kinase C in estradiol-induced luteinizing hormone receptor (lhcgr) expression in zebrafish ovarian follicle cells
Q88649842Extranuclear signaling by ovarian steroids in the regulation of sexual receptivity
Q34206778Gonadal steroids differentially modulate the actions of orphanin FQ/nociceptin at a physiologically relevant circuit controlling female sexual receptivity
Q33774774Integrating Neural Circuits Controlling Female Sexual Behavior
Q37288111Membrane estradiol signaling in the brain
Q24613623Membrane estrogen receptor regulation of hypothalamic function
Q36392753Membrane-initiated estradiol actions mediate structural plasticity and reproduction.
Q36794676Membrane-initiated estradiol signaling in immortalized hypothalamic N-38 neurons
Q34237244Membrane-initiated estradiol signaling induces spinogenesis required for female sexual receptivity.
Q35971276Membrane-initiated estradiol signaling regulating sexual receptivity
Q35087316Membrane-initiated non-genomic signaling by estrogens in the hypothalamus: cross-talk with glucocorticoids with implications for behavior.
Q48514095Milestones on Steroids and the Nervous System: 10 years of basic and translational research.
Q37092820Modulation of the arcuate nucleus-medial preoptic nucleus lordosis regulating circuit: a role for GABAB receptors
Q36328202Neurosteroids, trigger of the LH surge
Q35534339Orphanin FQ in the mediobasal hypothalamus facilitates sexual receptivity through the deactivation of medial preoptic nucleus mu-opioid receptors
Q35000991Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents
Q37154938Physiology of membrane oestrogen receptor signalling in reproduction.
Q93075361Plasma membrane G protein-coupled estrogen receptor 1 (GPER) mediates rapid estradiol facilitation of sexual receptivity through the orphanin-FQ-ORL-1 system in estradiol primed female rats
Q36985061Receptor subtypes and signal transduction mechanisms contributing to the estrogenic attenuation of cannabinoid-induced changes in energy homeostasis
Q35034937Role of neuronal nitric oxide synthase in the estrogenic attenuation of cannabinoid-induced changes in energy homeostasis
Q34548746Tamoxifen and ICI 182,780 activate hypothalamic G protein-coupled estrogen receptor 1 to rapidly facilitate lordosis in female rats
Q37619476Temporal and concentration-dependent effects of oestradiol on neural pathways mediating sexual receptivity.
Q50226059The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction.
Q35971868The Neurosteroid Progesterone Underlies Estrogen Positive Feedback of the LH Surge
Q35214338β-arrestin regulates estradiol membrane-initiated signaling in hypothalamic neurons

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